Geriatric pharmacology MCQs – Anesthesia

By: Prof. Dr. Fazal Rehman Shamil | Last updated: September 13, 2024

  • Why is dosing of anesthetic agents often reduced in elderly patients?
    a) Decreased hepatic metabolism
    b) Increased renal clearance
    c) Enhanced drug absorption
    d) Decreased body fatAnswer: a) Decreased hepatic metabolism
  • What is a common consequence of decreased renal function in elderly patients receiving anesthesia?
    a) Prolonged drug elimination
    b) Enhanced drug clearance
    c) Increased metabolism
    d) Decreased drug sensitivityAnswer: a) Prolonged drug elimination
  • Which physiological change in elderly patients affects drug distribution?
    a) Increased muscle mass
    b) Increased body fat
    c) Enhanced liver function
    d) Decreased plasma protein levelsAnswer: b) Increased body fat
  • How does decreased hepatic function in elderly patients affect anesthetic drug metabolism?
    a) Prolonged drug action
    b) Increased clearance
    c) Enhanced drug metabolism
    d) Decreased drug sensitivityAnswer: a) Prolonged drug action
  • Which of the following is a common issue with using opioids in elderly patients?
    a) Increased risk of sedation
    b) Decreased pain relief
    c) Enhanced drug metabolism
    d) Reduced risk of adverse effectsAnswer: a) Increased risk of sedation
  • What is a primary concern when administering benzodiazepines to elderly patients?
    a) Prolonged sedation
    b) Enhanced pain relief
    c) Increased drug metabolism
    d) Decreased muscle relaxationAnswer: a) Prolonged sedation
  • Why might elderly patients experience increased sensitivity to anesthetic agents?
    a) Enhanced liver function
    b) Decreased renal clearance
    c) Increased muscle mass
    d) Decreased body fatAnswer: b) Decreased renal clearance
  • Which of the following factors contributes to altered drug distribution in elderly patients?
    a) Decreased lean body mass
    b) Increased plasma protein levels
    c) Enhanced hepatic metabolism
    d) Increased cardiac outputAnswer: a) Decreased lean body mass
  • What is a significant risk associated with the use of neuromuscular blockers in elderly patients?
    a) Prolonged neuromuscular blockade
    b) Enhanced muscle relaxation
    c) Decreased sensitivity
    d) Increased clearanceAnswer: a) Prolonged neuromuscular blockade
  • How does age-related decrease in muscle mass impact anesthetic drug dosage?
    a) Requires dosage adjustment
    b) No impact on dosage
    c) Increased drug clearance
    d) Decreased drug sensitivityAnswer: a) Requires dosage adjustment
  • Which anesthetic agents should be used cautiously in elderly patients due to their potential for prolonged effects?
    a) Benzodiazepines
    b) Opioids
    c) Local anesthetics
    d) Inhaled anestheticsAnswer: a) Benzodiazepines
  • What is a common issue with using long-acting sedatives in elderly patients?
    a) Prolonged sedation
    b) Enhanced drug metabolism
    c) Decreased sensitivity
    d) Increased muscle relaxationAnswer: a) Prolonged sedation
  • Which factor should be considered when choosing anesthetic agents for elderly patients with compromised renal function?
    a) Reduced drug clearance
    b) Enhanced drug absorption
    c) Increased liver metabolism
    d) Decreased drug sensitivityAnswer: a) Reduced drug clearance
  • How does decreased plasma protein levels in elderly patients affect anesthetic drug distribution?
    a) Increased free drug concentration
    b) Decreased drug absorption
    c) Enhanced drug metabolism
    d) Reduced drug clearanceAnswer: a) Increased free drug concentration
  • What is a key concern when managing pain in elderly patients using opioids?
    a) Risk of respiratory depression
    b) Decreased pain relief
    c) Enhanced drug metabolism
    d) Increased risk of allergic reactionsAnswer: a) Risk of respiratory depression
  • Which anesthetic technique might be preferred in elderly patients to minimize adverse effects?
    a) Regional anesthesia
    b) General anesthesia
    c) Sedation
    d) Local anesthesiaAnswer: a) Regional anesthesia
  • Why is it important to monitor cognitive function closely in elderly patients post-anesthesia?
    a) Risk of delirium and cognitive impairment
    b) Enhanced cognitive recovery
    c) Decreased pain sensitivity
    d) Increased muscle strengthAnswer: a) Risk of delirium and cognitive impairment
  • What is a common postoperative issue related to decreased mobility in elderly patients?
    a) Deep vein thrombosis
    b) Hyperglycemia
    c) Electrolyte imbalance
    d) Increased appetiteAnswer: a) Deep vein thrombosis
  • Which of the following is a consideration when administering local anesthetics to elderly patients?
    a) Risk of systemic toxicity
    b) Enhanced pain relief
    c) Decreased absorption
    d) Increased drug metabolismAnswer: a) Risk of systemic toxicity
  • What is a key consideration for fluid management in elderly patients undergoing surgery?
    a) Careful monitoring to avoid overload
    b) Increased fluid administration
    c) Reduced fluid intake
    d) No special considerationsAnswer: a) Careful monitoring to avoid overload
  • How does age-related decrease in hepatic function impact the choice of anesthetic agents?
    a) Prolonged effects of drugs
    b) Enhanced drug metabolism
    c) Decreased risk of toxicity
    d) Increased clearanceAnswer: a) Prolonged effects of drugs
  • Which condition should be monitored closely in elderly patients receiving anesthesia due to its potential impact on drug metabolism?
    a) Hepatic function
    b) Blood glucose levels
    c) Electrolyte balance
    d) Body temperatureAnswer: a) Hepatic function
  • What is a common postoperative complication in elderly patients with compromised lung function?
    a) Pneumonia
    b) Gastrointestinal bleeding
    c) Hyperglycemia
    d) HypertensionAnswer: a) Pneumonia
  • Why should elderly patients be carefully monitored for temperature changes post-anesthesia?
    a) Risk of hypothermia
    b) Risk of hyperthermia
    c) Increased appetite
    d) Decreased pain sensitivityAnswer: a) Risk of hypothermia
  • What is a significant concern with the use of sedatives in elderly patients?
    a) Risk of prolonged sedation
    b) Increased metabolism
    c) Decreased sensitivity
    d) Enhanced muscle relaxationAnswer: a) Risk of prolonged sedation
  • Which anesthetic technique might be chosen to minimize cognitive impairment in elderly patients?
    a) Regional anesthesia
    b) General anesthesia
    c) Sedation
    d) Local anesthesiaAnswer: a) Regional anesthesia
  • What should be considered when managing postoperative pain in elderly patients?
    a) Avoiding high-dose opioids
    b) Increasing sedatives
    c) Enhanced local anesthesia
    d) Decreasing monitoringAnswer: a) Avoiding high-dose opioids
  • Which of the following factors contributes to altered drug distribution in elderly patients?
    a) Decreased body water
    b) Increased muscle mass
    c) Enhanced liver function
    d) Decreased body fatAnswer: a) Decreased body water
  • How does decreased muscle mass in elderly patients impact neuromuscular blocker usage?
    a) Prolonged neuromuscular blockade
    b) Enhanced muscle relaxation
    c) Decreased sensitivity
    d) Increased clearanceAnswer: a) Prolonged neuromuscular blockade
  • What is a common challenge with the use of long-acting anesthetics in elderly patients?
    a) Prolonged duration of action
    b) Enhanced pain relief
    c) Decreased drug absorption
    d) Increased metabolismAnswer: a) Prolonged duration of action
  • Which drug property should be considered due to changes in body fat and lean mass in elderly patients?
    a) Volume of distribution
    b) Drug absorption rate
    c) Hepatic clearance
    d) Renal excretionAnswer: a) Volume of distribution
  • Why might elderly patients have an increased risk of postoperative delirium?
    a) Age-related brain changes
    b) Enhanced drug metabolism
    c) Decreased sensitivity to drugs
    d) Increased muscle massAnswer: a) Age-related brain changes
  • What is a common issue related to drug interactions in elderly patients?
    a) Increased risk of adverse effects
    b) Enhanced drug metabolism
    c) Decreased drug sensitivity
    d) Reduced drug absorptionAnswer: a) Increased risk of adverse effects
  • Which of the following should be monitored to prevent complications in elderly patients receiving anesthesia?
    a) Fluid balance
    b) Electrolyte levels
    c) Body temperature
    d) Blood glucose levelsAnswer: a) Fluid balance
  • What is a significant concern with the use of local anesthetics in elderly patients?
    a) Risk of systemic toxicity
    b) Decreased efficacy
    c) Increased pain perception
    d) Enhanced metabolismAnswer: a) Risk of systemic toxicity
  • How does decreased cardiac output in elderly patients affect drug pharmacokinetics?
    a) Altered drug distribution
    b) Increased drug clearance
    c) Enhanced metabolism
    d) Decreased sensitivityAnswer: a) Altered drug distribution
  • What is a common postoperative issue for elderly patients with impaired mobility?
    a) Deep vein thrombosis
    b) Hyperglycemia
    c) Dehydration
    d) Electrolyte imbalanceAnswer: a) Deep vein thrombosis
  • Which consideration is crucial when choosing sedatives for elderly patients?
    a) Risk of prolonged sedation
    b) Enhanced drug metabolism
    c) Increased absorption
    d) Decreased drug sensitivityAnswer: a) Risk of prolonged sedation
  • What is a key consideration for analgesia in elderly patients with cognitive impairment?
    a) Avoiding high-dose opioids
    b) Enhanced sedative use
    c) Increased local anesthesia
    d) Decreased monitoringAnswer: a) Avoiding high-dose opioids
  • Why should elderly patients be monitored closely for cardiovascular issues post-anesthesia?
    a) Risk of cardiovascular instability
    b) Decreased risk of hypertension
    c) Enhanced cardiac output
    d) Increased drug clearanceAnswer: a) Risk of cardiovascular instability
  • How does age-related decrease in body water affect drug distribution?
    a) Altered volume of distribution
    b) Increased drug clearance
    c) Enhanced metabolism
    d) Decreased sensitivityAnswer: a) Altered volume of distribution
  • What should be monitored to prevent postoperative complications in elderly patients?
    a) Fluid balance and electrolytes
    b) Body temperature
    c) Pain levels
    d) Blood glucoseAnswer: a) Fluid balance and electrolytes
  • Which factor is crucial in managing anesthetic agents for elderly patients with liver dysfunction?
    a) Adjusting drug dosages
    b) Increasing fluid intake
    c) Enhancing muscle relaxation
    d) Reducing monitoringAnswer: a) Adjusting drug dosages
  • What is a common concern with administering high doses of anesthetics to elderly patients?
    a) Increased risk of adverse effects
    b) Enhanced pain relief
    c) Decreased drug sensitivity
    d) Improved clearanceAnswer: a) Increased risk of adverse effects
  • How does decreased plasma albumin affect drug binding in elderly patients?
    a) Increased free drug concentration
    b) Enhanced drug absorption
    c) Decreased metabolism
    d) Reduced drug excretionAnswer: a) Increased free drug concentration
  • Which factor should be considered when managing sedation in elderly patients?
    a) Risk of prolonged sedation
    b) Decreased drug absorption
    c) Increased metabolism
    d) Enhanced muscle relaxationAnswer: a) Risk of prolonged sedation
  • What is a key consideration when selecting analgesics for elderly patients with renal impairment?
    a) Reduced renal clearance
    b) Enhanced drug absorption
    c) Increased hepatic metabolism
    d) Decreased sensitivityAnswer: a) Reduced renal clearance
  • What should be monitored to prevent postoperative delirium in elderly patients?
    a) Cognitive function and fluid balance
    b) Body temperature
    c) Pain levels
    d) Blood glucoseAnswer: a) Cognitive function and fluid balance
  • Which of the following factors impacts anesthetic drug clearance in elderly patients?
    a) Decreased renal function
    b) Increased body fat
    c) Enhanced liver function
    d) Decreased drug sensitivityAnswer: a) Decreased renal function
  • What is a common challenge with using inhaled anesthetics in elderly patients?
    a) Prolonged duration of action
    b) Enhanced pain relief
    c) Decreased risk of toxicity
    d) Increased metabolismAnswer: a) Prolonged duration of action

Topic-wise Anesthesia MCQs

  1. Anesthesiology MCQs
  2. Anesthesia Basics:
  3. Anesthesia Agents MCQs:
  4. Airway Management:
  5. Anesthesia Monitoring MCQs – Anesthesia:
  6. Regional Anesthesia MCQs :
  7. Patient Assessment and Optimization:
  8. Anesthesia Delivery Systems MCQs:
  9. Pediatric Anesthesia MCQs :
  10. Obstetric Anesthesia MCQs – Anesthesia:
  11. Anesthesia Complications and Emergencies MCQs:
  12. Post-Anesthesia Care MCQs:
  13. Geriatric Anesthesia:
  14. Ethics and Professionalism in Anesthesia MCQs:
  15. Simulation and Skills Training MCQs :