Drug Design and development MCQ’s Quizlet bank

1: The strongest hydrogen bond acceptor…

a) amine nitrogen

b) aniline nitrogen 

c) carboxylate oxygen

d) amide nitrogen

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2: Different protein subunits in a multiprotein complex are…

a) tertiary structure

b) primary structure

c) secondary structure

d) quaternary structure

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3: Which statement is not true about regarding transport proteins?

a) present in cell membranes

b) carry polar molecules across the hydrophobic cell membrane

c) Transport amino acids across cell membranes

d) transport hydrophobic steroids across cell membranes

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4: —— is not a neurotransmitter?

a) cyclic AMP

b) noradrenaline

c) dopamine

d) acetylcholine

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5: A typical messenger for a tyrosine kinase linked receptor?

a) growth factors

b) cytokines

c) insulin

d) acetylcholine

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6. The process by which DNA is copied to produce two daughter DNA molecules is…

a) translation

b) transcription

c) reproduction

d) replication

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7. Agents act as irreversible inhibitors are…

a) statins

b) protease inhibitors

c) sulphonamides

d) penicilllins

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8. Which one infection could be orally treated with an antibacterial agent?

a) lung infection

b) brain infection

c) kidney infection

d) gut infection

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9. Drugs was not isolated from a natural source is…

a) isoniazid

b) artemisinin

c) quinine

d) morphine

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10. Strategies that increase the polarity and water solubility of a drug is…

a) Replacing an aromatic ring

b) Replacing an alkyl group

c) Removing polar functional groups

d) Adding extra alkyl groups

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11. Best describes the mechanism of action for fluoroquinolones is…

a) Antisense agent

b) Alkylating agent

c) Topoisomerase poison

d) Chain cutter

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12. Which of the following microorganism has been associated with the appearance of ulcers?

a) Enterococcus faecalis

b) Helicobacter pylori

c) Eschericia coli

d) Staphylococcus aureus

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