Neuromuscular blocking agents| Anesthesia Basics

By: Prof. Dr. Fazal Rehman | Last updated: September 13, 2024

Which neurotransmitter is the main target of neuromuscular blocking drugs in order to cause muscle relaxation?  
  1. A) Cholinergic acetamide
  2. B) GABA
(C) Dopamine
  1. D) A dopamine
Answer: Acetylcholine   What is the main clinical application of neuromuscular blocking agents?  
  1. A) Creating anesthesia
  2. B) Sustaining anesthesia
  3. C) Relaxing muscles while performing surgery
  4. D) Pain relief
Answer: C) Relaxing muscles while performing surgery   Which neuromuscular blocking agent causes long-term depolarization of muscles ?   A Vecuronium
  1. B) Rocuronium A
  2. C) Choline succinylcholine
  3. D) Aquarium
Answer: C) Choline succinylcholine   How do depolarizing neuromuscular blocking drugs, such as succinylcholine, work?  
  1. A) Acetylcholinesterase Inhibition
  2. B) Acetylcholine receptor activation
  3. C) Preventing the release of acetylcholine
  4. D) Extended binding to cholinergic receptors
Answer: B) Acetylcholine receptor activation   Because of its quick onset and brief duration of action, which neuromuscular blocking drug is frequently utilized during endotracheal intubation?
  1. Rocuronium
  2. B) Vecuronium
  3. C) Choline succinylcholine
  4. D) Aquarium
Answer: C) Choline succinylcholine   What is the main drawback of neuromuscular blocking drugs that depolarize, such as succinylcholine?  
  1. A) Extended duration of action
  2. B) Potential for histamine release
  3. C) Limited alternatives for reversal
  4. D) Some patient populations exhibit resistance.
Answer: C) Limited alternatives for reversal   Which neuromuscular blocking drug, because of its intermediate duration of action, is frequently chosen for lengthy surgical procedures?  
  1. A) Isoproterone
  2. B) Atracurium,
  3. C) Vecuronium,
D)Succinylcholine, Answer  A) Isoproterone   What is the main mode of action of drugs that prevent neuromuscular depolarization?  
  1. A) Acetylcholine receptor stimulation
  2. B) Acetylcholinesterase Inhibition
  3. C) Acetylcholine release blockade
  4. D) At acetylcholine receptors, competitive inhibition
Answer D   At acetylcholine receptors, competitive inhibition   Which element affects how long non-depolarizing neuromuscular blocking drugs last?  
  1. A) The dose that was given
  2. B) Hepatic metabolism
  3. C) Body distribution
  4. D) Excretion from the kidneys
Answer: B) Hepatic metabolism   What is the main drawback of succinylcholine use in people who have specific medical conditions?  
  1. A) Reactions to allergens
  2. B) Extended duration of effect C) Danger of cancerous hyperthermia
  3. D) Hyperkalemia.
Answer  D) Hyperkalemia.   In the intensive care unit, what kind of neuromuscular blocking drug is frequently used to relax muscles during mechanical ventilation?  
  1. A) Rocuronium
  2. B) Atracurium,
  3. C) Vecuronium
  4. D) Succinylcholine,
Answer  A) Rocuronium   What is the main benefit of rocuronium for muscular relaxation as opposed to succinylcholine?  
  1. A) Quick start of action
  2. B) Brief activity duration
  3. C) Hyperkalemia is not a concern.
  4. D) The action’s depolarizing process
Answer   C) Hyperkalemia is not a concern.   What class of medication is most frequently used to reverse the effects of non-depolarizing neuromuscular blocking agents?  
  1. A) Medicines called benzodiazepines
  2. B) Substances called Opioids
  3. C) Inhibitors of acetylcholinesterase
  4. D) Agonistes alpha-adrenergic
  5. C) Inhibitors of acetylcholinesterase
  Because it is eliminated by the organs independently, which neuromuscular blocking medication is frequently prescribed to patients with hepatic or renal dysfunction?  
  1. A) Succinylcholine
  2. B) Vecuronium
  3. C) Rocuronium
  4. D) Aquarium
Answer, D) Atracurium   What is the main function of acetylcholinesterase inhibitors in counteracting the effects of blocking drugs that are neuromuscular?  
  1. A) Extending the relaxation of muscles
  2. B) Preventing the release of acetylcholine
  3. C) Isolating acetylcholine receptors
  4. D) Raising the neuromuscular junction’s acetylcholine concentrations
Answer: Raising the neuromuscular junction’s acetylcholine concentrations Which neuromuscular blocking medication is metabolized via Hoffman elimination and has a benzylisoquinolinium structure?  
  1. A) Succinylcholine
  2. B) Vecuronium
  3. C) Rocuronium
  4. D) Aquarium
Answer, D) Atracurium   What is the main benefit of neuromuscular blocking drugs in surgical procedures?  
  1. A) Pain relief
  2. B) Relaxing of the muscles
  3. C) Sedation
  4. D) Elevation of blood pressure
Answer: B) Relaxation of muscles   Which neuromuscular blocking medication is categorized as a non-depolarizing, long-acting medication that is frequently utilized during lengthy surgical procedures?  
  1. A) Isoproterone
  2. B) Succinylcholine
  3. C) Vecuronium
  4. D) Isopronium
Answer: D) Ipetronium   What is the main drawback of succinylcholine use in people who have specific medical conditions?  
  1. A) Reactions to allergens
  2. B) Extended duration of effect
  3. C) Danger of cancerous hyperthermia
  4. D) Elevated potassium
Answer: D) Elevated potassium   Topic-wise Anesthesia MCQs
  1. Anesthesiology MCQs
  2. Anesthesia Basics:
  3. Anesthesia Agents MCQs:
  4. Airway Management:
  5. Anesthesia Monitoring MCQs – Anesthesia:
  6. Regional Anesthesia MCQs :
  7. Patient Assessment and Optimization:
  8. Anesthesia Delivery Systems MCQs:
  9. Pediatric Anesthesia MCQs :
  10. Obstetric Anesthesia MCQs – Anesthesia:
  11. Anesthesia Complications and Emergencies MCQs:
  12. Post-Anesthesia Care MCQs:
  13. Geriatric Anesthesia:
  14. Ethics and Professionalism in Anesthesia MCQs:
  15. Simulation and Skills Training MCQs :

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