Bioinformatics Research Topics Ideas

By: Prof. Dr. Fazal Rehman | Last updated: February 3, 2024

List of Bioinformatics Research Topics Ideas for. 1. Data access control in the cloud computing environment for bioinformatics 2. The bioinformatics toolbox for circRNA discovery and analysis 3. Want to track pandemic variants faster? Fix the bioinformatics bottleneck 4. A constructivist-based proposal for bioinformatics teaching practices during lockdown 5. Virus-CKB: an integrated bioinformatics platform and analysis resource for COVID-19 research 6. Therapeutic targets and signaling mechanisms of vitamin C activity against sepsis: a bioinformatics study 7. Bioinformatics helping to mitigate the impact of COVID-19–Editorial 8. Network bioinformatics analysis provides insight into drug repurposing for COVID-19 9. Deep learning-based clustering approaches for bioinformatics 10. User-friendly bioinformatics pipeline gDAT (graphical downstream analysis tool) for analysing rDNA sequences 11. Bioinformatics analysis of SARS-CoV-2 to approach an effective vaccine candidate against COVID-19 12. The Bio3D packages for structural bioinformatics 13. Metabolic Basis of Creatine in Health and Disease: A Bioinformatics-Assisted Review 14. The European Bioinformatics Institute: empowering cooperation in response to a global health crisis 15. Epigenetic dysregulation of immune-related pathways in cancer: bioinformatics tools and visualization 16. Implementing FAIR data management within the German Network for Bioinformatics Infrastructure (de. NBI) exemplified by selected use cases 17. Bioinformatics resources for SARS-CoV-2 discovery and surveillance 18. Bioinformatics and system biology approach to identify the influences of SARS-CoV-2 infections to idiopathic pulmonary fibrosis and chronic obstructive … 19. Insights into mineralocorticoid receptor homodimerization from a combined molecular modeling and bioinformatics study 20. Analysis and identification of novel biomarkers involved in neuroblastoma via integrated bioinformatics 21. Bioinformatics resources facilitate understanding and harnessing clinical research of SARS-CoV-2 22. BioContainers Registry: Searching Bioinformatics and Proteomics Tools, Packages, and Containers 23. A Review of Pharmacological and Toxicological Effects of Sophora tonkinensis with Bioinformatics Prediction 24. Application of Multilayer Network Models in Bioinformatics 25. Identification of potential biomarkers of polycystic ovary syndrome via integrated bioinformatics analysis 26. Bioinformatics analysis and verification of gene targets for renal clear cell carcinoma 27. Bioinformatics tools developed to support BioCompute Objects 28. Bioinformatics-based prediction of conformational epitopes for Enterovirus A71 and Coxsackievirus A16 29. Emulsifier peptides derived from seaweed, methanotrophic bacteria, and potato proteins identified by quantitative proteomics and bioinformatics 30. … of the molecular targets and mechanisms of compound mylabris capsules for hepatocellular carcinoma treatment through network pharmacology and bioinformatics … 31. Improving the Thermostability of Xylanase A from Bacillus subtilis by Combining Bioinformatics and Electrostatic Interactions Optimization 32. Physical exercise, obesity, inflammation and neutrophil extracellular traps (NETs): a review with bioinformatics analysis 33. MMP7 as a potential biomarker of colon cancer and its prognostic value by bioinformatics analysis 34. Bioinformatics: new tools and applications in life science and personalized medicine 35. OPCML Methylation and the Risk of Ovarian Cancer: A Meta and Bioinformatics Analysis 36. … mechanisms of GegenQinlian decoction on improving insulin resistance in adipose, liver, and muscle tissue by integrating system pharmacology and bioinformatics … 37. Determination of Potential Therapeutic Targets and Prognostic Markers of Ovarian Cancer by Bioinformatics Analysis 38. Structure–function engineering of novel fish gelatin-derived multifunctional peptides using high-resolution peptidomics and bioinformatics 39. Chemical composition, biological properties and bioinformatics analysis of two Caesalpina species: A new light in the road from nature to pharmacy shelf 40. … Cloud-Based Tutorials That Combine Bioinformatics Software, Interactive Coding, and Visualization Exercises for Distance Learning on Structural Bioinformatics 41. Functional characterization of ABCC8 variants of unknown significance based on bioinformatics predictions, splicing assays, and protein analyses: Benefits for the … 42. Integrative pharmacological mechanism of vitamin C combined with glycyrrhizic acid against COVID-19: findings of bioinformatics analyses 43. NGS-µsat: Bioinformatics framework supporting high throughput microsatellite genotyping from next generation sequencing platforms 44. Integrated bioinformatics analysis for the identification of key genes and signaling pathways in thyroid carcinoma 45. Integrative bioinformatics and omics data source interoperability in the next-generation sequencing era 46. Comprehensive bioinformatics analysis reveals kinase activity profiling associated with heart failure 47. Nimodipine attenuates dibutyl phthalate-induced learning and memory impairment in kun ming mice: An in vivo study based on bioinformatics analysis 48. Construction of circRNA-miRNA-mRNA network in the pathogenesis of recurrent implantation failure using integrated bioinformatics study 49. Bioinformatics analysis of differentially expressed miRNAs in non-small cell lung cancer 50. A systematic evaluation of bioinformatics tools for identification of long noncoding RNAs 51. Using Integrated Bioinformatics Analysis to Identify Abnormally Methylated Differentially Expressed Genes in Hepatocellular Carcinoma 52. Bioinformatics analysis of the microRNA-mRNA network in sebaceous gland carcinoma of the eyelid 53. A Bioinformatics Pipeline to Identify a Subset of SNPs for Genomics-Assisted Potato Breeding 54. Bioinformatics analysis of candidate genes involved in ethanol-induced microtia pathogenesis based on a human genome database: GeneCards 55. Bioinformatics and machine learning methodologies to identify the effects of central nervous system disorders on glioblastoma progression 56. Integrative analysis of miRNA–mRNA network in high altitude retinopathy by bioinformatics analysis 57. Screening and verification of hub genes involved in osteoarthritis using bioinformatics 58. Identification of a Gene Prognostic Signature for Oral Squamous Cell Carcinoma by RNA Sequencing and Bioinformatics 59. TRIB3 Promotes the Malignant Progression of Bladder Cancer: An Integrated Analysis of Bioinformatics and in vitro Experiments 60. Identified GNGT1 and NMU as Combined Diagnosis Biomarker of Non-Small-Cell Lung Cancer Utilizing Bioinformatics and Logistic Regression 61. A bioinformatics WGS workflow for clinical Mycobacterium tuberculosis complex isolate analysis, validated using a reference collection extensively characterized with … 62. A bioinformatics Approach for Identification of the core ontologies and signature genes of Pulmonary Disease and Associated Disease 63. Author Correction: Single-cell RNA sequencing technologies and bioinformatics pipelines 64. A new bioinformatics tool to recover missing gene expression in single-cell RNA sequencing data 65. Comprehensive analysis of PLOD family members in low-grade gliomas using bioinformatics methods 66. Identification of four genes and biological characteristics associated with acute spinal cord injury in rats integrated bioinformatics analysis 67. Identification of a prognostic gene signature of colon cancer using integrated bioinformatics analysis 68. Identification of Inflammatory Genes, Pathways, and Immune Cells in Necrotizing Enterocolitis of Preterm Infant by Bioinformatics Approaches 69. Bioinformatics Resources for RNA Editing 70. … /immune system-specific expressed genes are considered as the potential biomarkers for the diagnosis of early rheumatoid arthritis through bioinformatics … 71. A Critical Review on the Application of Artificial Neural Network in Bioinformatics 72. Identification of candidate biomarkers of liver hydatid disease via microarray profiling, bioinformatics analysis, and machine learning 73. Identification of Hub Genes in Different Stages of Colorectal Cancer through an Integrated Bioinformatics Approach 74. Key Genes and Molecular Mechanism Investigation in the Synthesis of Maize Quercetin Based on SNP and Bioinformatics Analysis 75. Bioinformatics analysis of common key genes and pathways of intracranial, abdominal, and thoracic aneurysms 76. A Bioinformatics Systems Biology Analysis of the Current Oral Proteomic Biomarkers and Implications for Diagnosis and Treatment of External Root Resorption 77. Bioinformatics Analyses of Potential miRNA-mRNA Regulatory Axis in HBV-related Hepatocellular Carcinoma 78. … the Mechanisms and Molecular Targets of Qishen Yiqi Formula for the Treatment of Pulmonary Arterial Hypertension using a Bioinformatics/Network Topology-based … 79. Introduction to Unsupervised Learning in Bioinformatics 80. Insight into molecular profile changes after skeletal muscle contusion using microarray and bioinformatics analyses 81. Bioinformatics analysis and biochemical characterisation of ABC transporter-associated periplasmic substrate-binding proteins ModA and MetQ from Helicobacter … 82. Identification of biomarkers and construction of a microRNA mRNA regulatory network for clear cell renal cell carcinoma using integrated bioinformatics … 83. Identifying the p65-Dependent Effect of Sulforaphene on Esophageal Squamous Cell Carcinoma Progression via Bioinformatics Analysis 84. Clinical heterogeneity of the SLC26A4 gene in UAE patients with hearing loss and bioinformatics investigation of DFNB4/Pendred syndrome missense mutations 85. Identification of differentially expressed genes, signaling pathways and immune infiltration in rheumatoid arthritis by integrated bioinformatics analysis 86. Bioinformatics in Plant Pathology 87. Identification of hub genes in triple-negative breast cancer by integrated bioinformatics analysis 88. Functional Bioinformatics Analyses of the Matrisome and Integrin Adhesome 89. Identification of potential markers for differentiating epithelial ovarian cancer from ovarian low malignant potential tumors through integrated bioinformatics … 90. Integrated bioinformatics analysis reveals novel key biomarkers and potential candidate small molecule drugs in gestational diabetes mellitus 91. … Neurotrophic Factor Functions as a Potential Candidate Gene in Obstructive Sleep Apnea Based on a Combination of Bioinformatics and Targeted Capture … 92. Bioinformatics analysis indicates that microRNA 628 5p overexpression may alleviate Alzheimer’s disease by targeting TYROBP 93. POS0851 IDENTIFICATION OF HUB GENES AND PATHWAYS IN DERMATOMYOSITIS BY BIOINFORMATICS ANALYSIS 94. Bioinformatics analysis of Myelin Transcription Factor 1 95. Development and Optimization of Clinical Informatics Infrastructure to Support Bioinformatics at an Oncology Center 96. A Systems Bioinformatics Approach to Interconnect Biological Pathways 97. Bioinformatics identification of green tea anticancer properties: a network-based approach 98. Diatom metabarcoding and microscopic analyses from sediment samples at Lake Nam Co, Tibet: The effect of sample-size and bioinformatics on the identified … 99. Bioinformatics Applied to the Development of Biomolecules of Pharmaceutical Interest 100. Bioinformatics analysis of WRKY transcription factors in grape and their potential roles prediction in sugar and abscisic acid signaling pathway 101. The clinical and prognostic significance of LGR5 in GC: A meta-analysis of IHC assay and bioinformatics analysis. 102. Bioinformatics Investigation and Contribution of Other Chromosomes Besides Chromosome 21 in the Risk of Down Syndrome Development 103. Network Pharmacological Analysis through a Bioinformatics Approach of Novel NSC765600 and NSC765691 Compounds as Potential Inhibitors of CCND1/CDK4 … 104. Cohort Identification for Translational Bioinformatics Studies 105. Advances in Omics and Bioinformatics Tools for Phyllosphere Studies 106. Harmonic Progression in Bioinformatics and Recurrent Series in Inherited Biostructures 107. OverCOVID: an integrative web portal for SARS-CoV-2 bioinformatics resources 108. Statistical and Bioinformatics Analysis of Data from Bulk and Single-Cell RNA Sequencing Experiments 109. A Bioinformatics Tutorial for Comparative Development Genomics in Diverse Meiofauna 110. Multidrug resistance protein structure of Trypanosoma evansi isolated from buffaloes in Ngawi District, Indonesia: A bioinformatics analysis 111. Integrative Bioinformatics Analysis Reveals Noninvasive miRNA Biomarkers for Lung Cancer 112. Quantifying plasmid dynamics using single-cell microfluidics and image bioinformatics 113. Identification of four differentially expressed genes associated with acute and chronic spinal cord injury based on bioinformatics data 114. Identification of key pathways and gene expression in the activation of mast cells via calcium flux using bioinformatics analysis 115. Identification of Significant Genes and Therapeutic Agents for Breast Cancer by Integrated Bioinformatics 116. Using supercomputer to finish M1 Bioinformatics Exercise from Ogata Lab 117. Transcriptomic Alterations Induced by Vemurafenib After Treatment of Melanoma: A Comprehensive Bioinformatics Analysis 118. … OF MOLECULAR PHENOTYPES AND IMMUNE CELL INFILTRATION IN PSORIATIC ARTHRITIS PATIENTS’SKIN TISSUES BY INTEGRATED BIOINFORMATICS … 119. Bioinformatics: A New Insight Tool to Deal with Environment Management 120. Identification of acute spinal cord injury and autophagy-related potential key genes, pathways, and targeting drugs through bioinformatics analysis 121. Identification of Molecular Mechanisms Underlying Sex-Associated Differences in the Chronic Obstructive Pulmonary Disease through Bioinformatics Analysis 122. Bioinformatics and In Vitro Studies Reveal the Importance of p53, PPARG and Notch Signaling Pathway in Inhibition of Breast Cancer Stem Cells by … 123. Bioinformatics Approaches for Functional Prediction of Long Noncoding RNAs 124. A Comprehensive Phylogenetic and Bioinformatics Survey of Lectins in the Fungal kingdom 125. Deep networks and network representation in bioinformatics 126. Identifying Potential Prognostic Biomarkers Associated With Clinicopathologic Characteristics of Hepatocellular Carcinoma by Bioinformatics Analysis 127. Identification of key pathways and hub genes in the myogenic differentiation of pluripotent stem cell: a bioinformatics and experimental study 128. … of intestinal microbiome in a process of faecal microbiota transplantation in a patient with Clostridioides difficile infection: NGS analysis with different bioinformatics … 129. Clinical significance of long noncoding RNA MNX1-AS1 in human cancers: a meta-analysis of cohort studies and bioinformatics analysis based on TCGA datasets 130. Anticancer property of Zika virus proteins: Lack of evidence from predictive clinical bioinformatics study 131. Identification of Differentially Expressed Genes Using Deep Learning in Bioinformatics 132. Bioinformatics Analysis Predicts hsa_circ_0026337/miR-197-3p as a Potential Oncogenic ceRNA Network for Non-small Cell Lung Cancers 133. … Molecular Mechanism of Xiao Huoluo Pills in the Treatment of Cartilage Degeneration of Knee Osteoarthritis Based on Bioinformatics Analysis and Molecular … 134. A bioinformatics analysis of differentially expressed proteins in plasma exosome of acute-on-chronic liver failure patients with different prognoses 135. Bioinformatics Analyses of Serine Acetyltransferase (SAT) Gene Family in Rice (Oryza sativa) and their Expressions under Salt Stress 136. Expression profiling and bioinformatics analysis of exosomal long noncoding RNAs in patients with myasthenia gravis by RNA sequencing 137. Bioinformatics Analysis in Different Expression Genes and Potential Pathways of CD4+ Cells in Childhood Allergic Asthma 138. … Key Genes in Anaplastic Thyroid Cancer Using Bioinformatics AnalysisIdentification of Potential Key Genes in Anaplastic Thyroid Cancer using Bioinformatics … 139. … predicts poor prognosis in patients with surgically resected Lung Adenocarcinoma: A study based on Immunohistochemical Analysis and Bioinformatics 140. High-throughput screening and bioinformatics analysis of 2,000 177Lu-PSMA and Radiotherapy+ drug combinations 141. Bioinformatics Analysis of C3 and CXCR4 act as Potential Prognostic Biomarkers in Clear Cell Renal Cell Carcinoma (ccRCC) 142. Complexity matters: Evaluating the impact of bioinformatics parameters on eukaryotic MOTU delimitation and taxonomy assignment 143. Bioinformatics analysis of the expression and role of microRNA-221-3p in head and neck squamous cell carcinoma 144. In-silico analysis of BCL2 gene using multiple bioinformatics tools to identify the most lethal mutations that are crucial for its structural and functional integrity 145. A Novel Ferroptosis-related Lncrna Prognostic Signature for Colorectal Cancer by Bioinformatics Analysis 146. Correction to “Complementary Genomic Bioinformatics and Chemical Approaches Facilitate the Absolute Structure Assignment of Ionostatin, a Linear Polyketide from … 147. Correction to: A Bioinformatics Tutorial for Comparative Genomics of Meiofauna 148. Want to track pandemic variants faster? Fix the bioinformatics bottleneck 149. Use of Bioinformatics Technologies and Databases to Teach Analysis of Genetic Sequences to Undergraduate Students in Physics, Biotechnology, and … 150. A Single-Cell Bioinformatics Analysis of the Host Transcriptional Response to Infection Consisting of Natural Combinations of Influenza A Virus Gene Segments 151. Erratum to comprehensive bioinformatics analysis of the TP53 signaling pathway in Wilms’ tumor 152. Bioinformatics Analysis of DNA Methylation Through Bisulfite Sequencing Data 153. Correction to: Development and Optimization of Clinical Informatics Infrastructure to Support Bioinformatics at an Oncology Center 154. Comparison of bioinformatics pipelines for eDNA metabarcoding data analysis of fish populations in Czech reservoirs 155. Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma 156. Bioinformatics Analysis of the Lycopene ß-Cyclase Gene in Jujube (Ziziphus jujube Mill) 157. Gene expression collective data analysis for studying the effects of high-LET ionizing radiation: A bioinformatics approach 158. CoV-AbDab: the coronavirus antibody database 159. BERT4Bitter: a bidirectional encoder representations from transformers (BERT)-based model for improving the prediction of bitter peptides 160. Sanhuang Jiangtang tablet protects type 2 diabetes osteoporosis via AKT-GSK3ß-NFATc1 signaling pathway by integrating bioinformatics analysis and experimental … 161. … Tuning onto Recurrent Neural Network and Long Short-Term Memory (RNN-LSTM) Network for Feature Selection in Classification of High-Dimensional Bioinformatics … 162. pyGenomeTracks: reproducible plots for multivariate genomic datasets 163. IS900 RFLP Analysis of Mycobacterium avium subsp. Paratuberculosis of Iranian Isolates and Analyze Using Bioinformatics Tools 164. Screening druggable targets and predicting therapeutic drugs for COVID-19 via integrated bioinformatics analysis 165. Supplementary Material to “Integrated analysis of label-free quantitative proteomics and bioinformatics reveal insights into signaling pathways in male breast … 166. … gallate interaction in SARS-CoV-2 spike-protein central channel with reference to the hydroxychloroquine interaction: bioinformatics and molecular docking study 167. CAFE: a software suite for analysis of paired-sample transposon insertion sequencing data 168. Multidrug resistance protein structure of Trypanosoma evansi isolated from buffaloes in Ngawi District, Indonesia: A bioinformatics analysis, Veterinary World, 14 (1) … 169. A Complete Bibliography of IEEE/ACM Transactions on Computational Biology and Bioinformatics 170. Ribbon: intuitive visualization for complex genomic variation 171. Bioinformatics analysis of gene expression profile and key pathways related to fatty infiltration after rotator cuff injury 172. Significance and Mechanisms Analyses of RB1 Mutation in Bladder Cancer Disease Progression and Drug Selection by Bioinformatics Analysis 173. Towards Investigating the Role of Proprotein Convertase Subtilisin/Kexin Family (PCSK/7/9) in Cancer by Using Bioinformatics Motif Detection Technique 174. CNVfilteR: an R/bioconductor package to identify false positives produced by germline NGS CNV detection tools 175. Potential prediction of phenolic compounds in red ginger (Zingiber officinale var. rubrum) as an AT1R antagonist by bioinformatics approach for antihypertensive oral … 176. [PS][PS] Interval Versions of Statistical Techniques, with Applications to Environmental Analysis, Bioinformatics, and Privacy in Statistical Databases 177. Using Interpretable Deep Learning to Model Cancer Dependencies 178. iCarPS: a computational tool for identifying protein carbonylation sites by novel encoded features 179. iEnhancer-XG: interpretable sequence-based enhancers and their strength predictor 180. Outlier detection in Bioinformatics with Mixtures of Gaussian and heavy-tailed distributions 181. A Modelling Framework for Embedding-based Predictions for Compound-Viral Protein Activity 182. SimText: A text mining framework for interactive analysis and visualization of similarities among biomedical entities 183. UniBioDicts: unified access to biological dictionaries 184. GraphDTA: Predicting drug–target binding affinity with graph neural networks 185. COVID-KOP: integrating emerging COVID-19 data with the ROBOKOP database 186. Discovering footprints of evolutionary chromatin response to transposons activity: merging biophysics with bioinformatics 187. mzRAPP: a tool for reliability assessment of data pre-processing in non-targeted metabolomics 188. In-silico prediction of in-vitro protein liquid-liquid phase separation experiments outcomes with multi-head neural attention 189. Pentraxin 3 is a diagnostic and prognostic marker for ovarian epithelial cancer patients based on comprehensive bioinformatics and experiments 190. ViralMSA: Massively scalable reference-guided multiple sequence alignment of viral genomes 191. PBSIM2: a simulator for long-read sequencers with a novel generative model of quality scores 192. MELODI Presto: a fast and agile tool to explore semantic triples derived from biomedical literature 193. UglyTrees: a browser-based multispecies coalescent tree visualizer 194. Mutation-Simulator: fine-grained simulation of random mutations in any genome 195. SAIGEgds—an efficient statistical tool for large-scale PheWAS with mixed models 196. Unsupervised protein embeddings outperform hand-crafted sequence and structure features at predicting molecular function 197. Detecting Let-7 isoforms of Salmonids by bioinformatics data 198. PICS2: next-generation fine mapping via probabilistic identification of causal SNPs 199. mixtureS: a novel tool for bacterial strain genome reconstruction from reads 200. Genozip: a universal extensible genomic data compressor 201. A systems-biology model of the tumor necrosis factor (TNF) interactions with TNF receptor 1 and 2 202. Early cancer detection from genome-wide cell-free DNA fragmentation via shuffled frog leaping algorithm and support vector machine 203. MAT2: Manifold alignment of single-cell transcriptomes with cell triplets 204. MDeePred: novel multi-channel protein featurization for deep learning-based binding affinity prediction in drug discovery 205. Narrative Scientific Data Visualization in an Immersive Environment 206. Assessing the fit of the multi-species network coalescent to multi-locus data 207. Predicting candidate genes from phenotypes, functions and anatomical site of expression 208. BamSnap: a lightweight viewer for sequencing reads in BAM files 209. ILoReg: a tool for high-resolution cell population identification from single-cell RNA-seq data 210. Characterizing protein conformers by cross-linking mass spectrometry and pattern recognition 211. GraphQA: protein model quality assessment using graph convolutional networks 212. CaNDis: a web server for investigation of causal relationships between diseases, drugs and drug targets 213. ProkSeq for complete analysis of RNA-seq data from prokaryotes 214. HATK: HLA analysis toolkit 215. A combined recall and rank framework with online negative sampling for chinese procedure terminology normalization 216. Systematic determination of the mitochondrial proportion in human and mice tissues for single-cell RNA-sequencing data quality control 217. DELPHI: accurate deep ensemble model for protein interaction sites prediction 218. SOLQC: Synthetic oligo library quality control tool 219. shinyÉPICo: A graphical pipeline to analyze Illumina DNA methylation arrays 220. dream: Powerful differential expression analysis for repeated measures designs 221. ASimulatoR: splice-aware RNA-Seq data simulation 222. SARS-CoV-2 Through the Lens of Computational Biology: How bioinformatics is playing a key role in the study of the virus and its origins 223. Interactive gene networks with KNIT 224. A database of flavivirus RNA structures with a search algorithm for pseudoknots and triple base interactions 225. IGD: high-performance search for large-scale genomic interval datasets 226. NetSets. js: a JavaScript framework for compositional assessment and comparison of biological networks through Venn-integrated network diagrams 227. Proteo-chemometrics interaction fingerprints of protein–ligand complexes predict binding affinity 228. GWASinspector: comprehensive quality control of genome-wide association study results 229. FASTRAL: Improving scalability of phylogenomic analysis 230. A network-based deep learning methodology for stratification of tumor mutations 231. Deuteros 2.0: peptide-level significance testing of data from hydrogen deuterium exchange mass spectrometry 232. The Russian Drug Reaction Corpus and neural models for drug reactions and effectiveness detection in user reviews 233. eHSCPr discriminating the cell identity involved in endothelial to hematopoietic transition 234. EM-stellar: benchmarking deep learning for electron microscopy image segmentation 235. mzRecal: universal MS1 recalibration in mzML using identified peptides in mzIdentML as internal calibrants 236. MR-Clust: clustering of genetic variants in Mendelian randomization with similar causal estimates 237. PyRice: a Python package for querying Oryza sativa databases 238. Bipartite graph-based approach for clustering of cell lines by gene expression-drug response associations 239. The iPPI-DB initiative: A Community-centered database of Protein-Protein Interaction modulators 240. MotifGenie: A Python Application for Searching Transcription Factor Binding Sequences Using ChIP-Seq Datasets 241. Network-guided search for genetic heterogeneity between gene pairs 242. Annotating high-impact 5′ untranslated region variants with the UTRannotator 243. Few shot domain adaptation for in situ macromolecule structural classification in cryoelectron tomograms 244. Recognition of small molecule-RNA binding sites using RNA sequence and structure 245. Machine Boss: rapid prototyping of bioinformatic automata 246. Automated download and clean-up of family-specific databases for kmer-based virus identification 247. PC2P: Parameter-free network-based prediction of protein complexes 248. CRAFT: Compact genome Representation toward large-scale Alignment-Free daTabase 249. CABEAN: a software for the control of asynchronous Boolean networks 250. Analysis of Collagen type X alpha 1 (COL10A1) expression and prognostic significance in gastric cancer based on bioinformatics 251. Large-scale entity representation learning for biomedical relationship extraction 252. Higher infectivity of the SARS-CoV-2 new variants is associated with K417N/T, E484K, and N501Y mutants: An insight from structural data 253. EARRINGS: an efficient and accurate adapter trimmer entails no a priori adapter sequences 254. ProteomeExpert: a docker image based web-server for exploring, modeling, visualizing, and mining quantitative proteomic data sets 255. PhyloCorrelate: inferring bacterial gene-gene functional associations through large-scale phylogenetic profiling 256. VIDHOP, viral host prediction with Deep Learning 257. CCmed: cross-condition mediation analysis for identifying replicable trans-associations mediated by cis-gene expression 258. Network-adjusted Kendall’s Tau Measure for Feature Screening with Application to High-dimensional Survival Genomic Data 259. Comparison of observation-based and model-based identification of alert concentrations from concentration–expression data 260. xGAP: A python based efficient, modular, extensible and fault tolerant genomic analysis pipeline for variant discovery 261. P69. 02 Identification of Potential Core Gene in Immune Infiltrates of EGFR Mutant Lung Adenocarcinoma using Bioinformatics Analysis 262. CellTracker: An Automated Toolbox for Single-Cell Segmentation and Tracking of Time-lapse Microscopy Images 263. Inferring cancer progression from single-cell sequencing while allowing mutation losses 264. ResiRole: residue-level functional site predictions to gauge the accuracies of protein structure prediction techniques 265. MendelVar: gene prioritization at GWAS loci using phenotypic enrichment of Mendelian disease genes 266. Robust and ultrafast fiducial marker correspondence in electron tomography by a two-stage algorithm considering local constraints 267. KORP-PL: a coarse-grained knowledge-based scoring function for protein–ligand interactions 268. A Method for Subtype Analysis with Somatic Mutations 269. PoSeiDon: a Nextflow pipeline for the detection of evolutionary recombination events and positive selection 270. FuSe: a tool to move RNA-Seq analyses from chromosomal/gene loci to functional grouping of mRNA transcripts 271. A statistical approach for tracking clonal dynamics in cancer using longitudinal next-generation sequencing data 272. Diamond: A Multi-Modal DIA Mass Spectrometry Data Processing Pipeline 273. TreeMap: a structured approach to fine mapping of eQTL variants 274. Co-phosphorylation networks reveal subtype-specific signaling modules in breast cancer 275. TSPTFBS: a docker image for Trans-Species Prediction of Transcription Factor Binding Sites in Plants 276. Lnc2Cancer 3.0: an updated resource for experimentally supported lncRNA/circRNA cancer associations and web tools based on RNA-seq and scRNA-seq data 277. Network approach to mutagenesis sheds insight on phage resistance in mycobacteria 278. QAlign: Aligning nanopore reads accurately using current-level modeling 279. Machine-OlF-Action: A unified framework for developing and interpreting machine-learning models for chemosensory research 280. Backward Pattern Matching on Elastic Degenerate Strings. 281. Coordinate Systems for Pangenome Graphs based on the Level Function and Minimum Path Covers. 282. CoRC: the COPASI R connector 283. MSL-ST: Development of Mass Spectral Library Search Tool to Enhance Compound Identification. 284. Genome-wide identification and bioinformatics characterization of superoxide dismutases in the desiccation-tolerant cyanobacterium Chroococcidiopsis … 285. Unpaired data empowers association tests 286. DataRemix: a universal data transformation for optimal inference from gene expression datasets 287. … -regulated Differentially Expressed Genes and Related Pathways in Hepatocellular Carcinoma: A Study Based on TCGA Database and Bioinformatics … 288. Discovering a sparse set of pairwise discriminating features in high-dimensional data 289. Gastric cancer-associated microRNA expression signatures: integrated bioinformatics analysis, validation, and clinical significance 290. Cataloguing experimentally confirmed 80.7 kb-long ACKR1 haplotypes from the 1000 Genomes Project database 291. BoardION: real-time monitoring of Oxford Nanopore sequencing instruments 292. Augur: a bioinformatics toolkit for phylogenetic analyses 293. TANTIGEN 2.0: a knowledge base of tumor T cell antigens and epitopes 294. Exploring the potential of Galangin in Cholangiocarcinoma cells using a bioinformatics approach 295. Efflux proteins at the blood-brain barrier: review and bioinformatics analysis (vol 48, pg 506, 2018) 296. GLEANER: a web server for GermLine cycle Expression ANalysis and Epigenetic Roadmap visualization 297. Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics 298. Advances in the prediction of mouse liver microsomal studies: From machine learning to deep learning 299. Advantages of using graph databases to explore chromatin conformation capture experiments 300. P* R* O* P: a web application to perform phylogenetic analysis considering the effect of gaps 301. Introduction to the JBCB Special Issue on Selected Papers from BICOB-2020 302. ViR: a tool to solve intrasample variability in the prediction of viral integration sites using whole genome sequencing data 303. Improving high-resolution copy number variation analysis from next generation sequencing using unique molecular identifiers 304. Genome-resolved metagenomics using environmental and clinical samples. 305. Set-theory based benchmarking of three different variant callers for targeted sequencing 306. Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells 307. Construction and Analysis of mRNA and lncRNA Regulatory Networks Reveal the Key Genes Associated with Prostate Cancer Related Fatigue During Localized … 308. Current RNA-seq methodology reporting limits reproducibility 309. Search for SINE repeats in the rice genome using correlation-based position weight matrices 310. AutoDTI++: deep unsupervised learning for DTI prediction by autoencoders 311. Mining Biomedical Texts for Pediatric Information. 312. Identification of Key mRNAs, miRNAs, and mRNA-miRNA Network Involved in Papillary Thyroid Carcinoma 313. RaacLogo: a new sequence logo generator by using reduced amino acid clusters 314. NGlyAlign: an automated library building tool to align highly divergent HIV envelope sequences 315. CeNet Omnibus: an R/Shiny application to the construction and analysis of competing endogenous RNA network 316. Measurements of venous oxygen saturation in the superior sagittal sinus using conventional 3D multiple gradient-echo MRI: Effects of flow velocity and acceleration 317. SARS-CoV-2 hot-spot mutations are significantly enriched within inverted repeats and CpG island loci 318. Six genes involved in prognosis of hepatocellular carcinoma identified by Cox hazard regression 319. Deep Learning-Based Experimentation for Predicting Secondary Structure of Amino Acid Sequence 320. A novel end-to-end method to predict RNA secondary structure profile based on bidirectional LSTM and residual neural network 321. MMFGRN: a multi-source multi-model fusion method for gene regulatory network reconstruction 322. Identification of genetic variations associated with drug resistance in non-small cell lung cancer patients undergoing systemic treatment 323. BugSeq: a highly accurate cloud platform for long-read metagenomic analyses 324. The complete genome sequence of Hafnia alvei A23BA; a potential antibiotic-producing rhizobacterium 325. Web tools to fight pandemics: the COVID-19 experience 326. Single-cell transcriptomic profiling of satellite glial cells in stellate ganglia reveals developmental and functional axial dynamics 327. Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research 328. Toll-like Receptor 4 Gene Polymorphisms in Chinese Population After Allogeneic Hematopoietic Stem Cell Transplantation 329. ReCGBM: a gradient boosting-based method for predicting human dicer cleavage sites 330. NIDM: network impulsive dynamics on multiplex biological network for disease-gene prediction 331. Comparison study of differential abundance testing methods using two large Parkinson disease gut microbiome datasets derived from 16S amplicon … 332. Interaction of Nucleic Acids: Hidden Order of Interaction 333. Identification of Glioma Specific Genes as Diagnostic and Prognostic Markers for Glioma 334. Visual4DTracker: a tool to interact with 3D+ t image stacks 335. Establishing a consensus for the hallmarks of cancer based on gene ontology and pathway annotations 336. Temperature and latitude correlate with SARS-CoV-2 epidemiological variables but not with genomic change worldwide 337. Comparing de novo transcriptome assembly tools in di-and autotetraploid non-model plant species 338. SPServer: split-statistical potentials for the analysis of protein structures and protein–protein interactions 339. Identifying the sequence specificities of circRNA-binding proteins based on a capsule network architecture 340. Network-based identification genetic effect of SARS-CoV-2 infections to Idiopathic pulmonary fibrosis (IPF) patients 341. MATHLA: a robust framework for HLA-peptide binding prediction integrating bidirectional LSTM and multiple head attention mechanism 342. DeepDist: real-value inter-residue distance prediction with deep residual convolutional network 343. CHTKC: a robust and efficient k-mer counting algorithm based on a lock-free chaining hash table 344. DeepLPI: a multimodal deep learning method for predicting the interactions between lncRNAs and protein isoforms 345. COVID-19: disease pathways and gene expression changes predict methylprednisolone can improve outcome in severe cases. 346. Modeling drug mechanism of action with large scale gene-expression profiles using GPAR, an artificial intelligence platform 347. Brain Interface: Nano-Scaled Device as an Improvement in the Process of Learning 348. Profile hidden Markov model sequence analysis can help remove putative pseudogenes from DNA barcoding and metabarcoding datasets 349. Grafting Methionine on 1F1 Ab Increases the Broad-Activity on HA Structural-Conserved Residues of H1, H2, and H3 Influenza a Viruses 350. Accurate prediction of multi-label protein subcellular localization through multi-view feature learning with RBRL classifier 351. Pathway Tools version 23.0 update: software for pathway/genome informatics and systems biology 352. A decade of de novo transcriptome assembly: Are we there yet? 353. Feature selection based on fuzzy joint mutual information maximization [J] 354. tidyMicro: a pipeline for microbiome data analysis and visualization using the tidyverse in R 355. A survey of gene expression meta-analysis: methods and applications 356. Drug perturbation gene set enrichment analysis (dpGSEA): a new transcriptomic drug screening approach 357. PCirc: random forest-based plant circRNA identification software 358. Alvis: a tool for contig and read ALignment VISualisation and chimera detection 359. Small noncoding RNA discovery and profiling with sRNAtools based on high-throughput sequencing 360. DeepDRK: a deep learning framework for drug repurposing through kernel-based multi-omics integration 361. CoronaPep: An Anti-coronavirus Peptide Generation Tool 362. Identification of deregulation mechanisms specific to cancer subtypes 363. Computational resources for identifying and describing proteins driving liquid–liquid phase separation 364. Successful identification of predictive profiles for infection utilising systems-level immune analysis: a pilot study in patients with relapsed and refractory multiple … 365. SCC: an accurate imputation method for scRNA-seq dropouts based on a mixture model 366. MicrobeAnnotator: a user-friendly, comprehensive functional annotation pipeline for microbial genomes 367. Propedia: a database for protein–peptide identification based on a hybrid clustering algorithm 368. Epidemiological data analysis of viral quasispecies in the next-generation sequencing era 369. Prediction of tumor purity from gene expression data using machine learning 370. Practical Workflow from High-Throughput Genotyping to Genomic Estimated Breeding Values (GEBVs) 371. Design powerful predictor for mRNA subcellular location prediction in Homo sapiens 372. First Complete Genome of the Thermophilic Polyhydroxyalkanoates Producing Bacterium Schlegelella thermodepolymerans DSM 15344 373. recoup: flexible and versatile signal visualization from next generation sequencing 374. Predicting chemosensitivity using drug perturbed gene dynamics 375. Learning curves for drug response prediction in cancer cell lines 376. Anticancer peptides prediction with deep representation learning features 377. Structured sparsity regularization for analyzing high-dimensional omics data 378. MADGAN: unsupervised medical anomaly detection GAN using multiple adjacent brain MRI slice reconstruction 379. Novel perspectives for SARS-CoV-2 genome browsing 380. DISTEVAL: a web server for evaluating predicted protein distances 381. Fast and Accurate Multiple Sequence Alignment with MSAProbs-MPI 382. Prediction of RNA-binding protein and alternative splicing event associations during epithelial–mesenchymal transition based on inductive matrix completion 383. BioMedR: an R/CRAN package for integrated data analysis pipeline in biomedical study 384. Murine induced pluripotent stem cell-derived neuroimmune cell culture models emphasize opposite immune-effector functions of interleukin 13-primed microglia and … 385. A novel essential protein identification method based on PPI networks and gene expression data 386. Repeat DNA expands our understanding of autism spectrum disorder 387. Error-corrected estimation of a diagnostic accuracy index of a biomarker against a continuous gold standard 388. Using deep neural networks and biological subwords to detect protein S-sulfenylation sites 389. ProtFold-DFG: protein fold recognition by combining Directed Fusion Graph and PageRank algorithm 390. G-Tric: generating three-way synthetic datasets with triclustering solutions 391. Twelve years of SAMtools and BCFtools 392. mixIndependR: a R package for statistical independence testing of loci in database of multi-locus genotypes 393. PredCID: prediction of driver frameshift indels in human cancer 394. Dualmarker: a flexible toolset for exploratory analysis of combinatorial dual biomarkers for clinical efficacy 395. A novel computational framework for genome-scale alternative transcription units prediction 396. H2V: a database of human genes and proteins that respond to SARS-CoV-2, SARS-CoV, and MERS-CoV infection 397. Isolating SARS-CoV-2 strains from countries in the same meridian: genome evolutionary analysis 398. Federated sharing and processing of genomic datasets for tertiary data analysis 399. SARS-CoV-2 3D database: understanding the coronavirus proteome and evaluating possible drug targets 400. Postoperative radiotherapy is associated with improved overall survival for alveolar ridge squamous cell carcinoma with adverse pathologic features 401. Mass spectrometry–based protein identification in proteomics—a review 402. CodAn: predictive models for precise identification of coding regions in eukaryotic transcripts 403. Genome-wide discovery of pre-miRNAs: comparison of recent approaches based on machine learning 404. Meta-i6mA: an interspecies predictor for identifying DNA N6-methyladenine sites of plant genomes by exploiting informative features in an integrative machine … 405. Graph and Convolution Recurrent Neural Networks for Protein-Compound Interaction Prediction 406. FoldRec-C2C: protein fold recognition by combining cluster-to-cluster model and protein similarity network 407. Next generation sequencing of SARS-CoV-2 genomes: challenges, applications and opportunities 408. A computational platform to identify origins of replication sites in eukaryotes 409. Toli c N, Jaitly N, Shaw JL, Adkins JN, Smith RD 410. Adverse events associated with potential drugs for COVID-19: a case study from real-world data 411. KFGRNI: A robust method to inference gene regulatory network from time-course gene data based on ensemble Kalman filter. 412. Updates to HCOP: the HGNC comparison of orthology predictions tool 413. Bicuspid aortic valve sparing root replacement 414. Unsupervised and self-supervised deep learning approaches for biomedical text mining 415. HapSolo: An optimization approach for removing secondary haplotigs during diploid genome assembly and scaffolding 416. Computational Antigen Discovery for Eukaryotic Pathogens Using Vacceed 417. Wireless Wi-Fi module Testing Procedure in Gigabyte Passive Optical Network to Optical Network Terminal of Equipment 418. Receiver for m-ary Radio Communication System Between Motile Objects in the Microwave Range 419. Impact of perioperative factors on nadir serum prostate-specific antigen levels after holmium laser enucleation of prostate 420. gutMEGA: a database of the human gut MEtaGenome Atlas 421. Computer-aided prediction and design of IL-6 inducing peptides: IL-6 plays a crucial role in COVID-19 422. Toxicological assessment of newly expressed proteins (NEPs) in genetically modified (GM) plants 423. SubLocEP: a novel ensemble predictor of subcellular localization of eukaryotic mRNA based on machine learning 424. Determining Cell Death Pathway and Regulation by Enrichment Analysis 425. The European Nucleotide Archive in 2020 426. iCysMod: an integrative database for protein cysteine modifications in eukaryotes 427. A review on viral data sources and search systems for perspective mitigation of COVID-19 428. Searching for universal model of amyloid signaling motifs using probabilistic context-free grammars 429. Current challenges and best-practice protocols for microbiome analysis 430. The Coronavirus Network Explorer: Mining a large-scale knowledge graph for effects of SARS-CoV-2 on host cell function 431. Deep-belief network for predicting potential miRNA-disease associations 432. DeepATT: a hybrid category attention neural network for identifying functional effects of DNA sequences 433. A molecular modelling approach for identifying antiviral selenium-containing heterocyclic compounds that inhibit the main protease of SARS-CoV-2: an in silico … 434. SG-LSTM-FRAME: A computational frame using sequence and geometrical information via LSTM to predict miRNA–gene associations 435. Common low complexity regions for SARS-CoV-2 and human proteomes as potential multidirectional risk factor in vaccine development 436. OrthoDB in 2020: evolutionary and functional annotations of orthologs 437. PDB-tools web: A user-friendly interface for the manipulation of PDB files 438. Comparative evaluation of full-length isoform quantification from RNA-Seq 439. SurvivalMeth: a web server to investigate the effect of DNA methylation-related functional elements on prognosis 440. The peripheral and core regions of virus-host network of COVID-19. 441. Accucopy: accurate and fast inference of allele-specific copy number alterations from low-coverage low-purity tumor sequencing data 442. Unveiling COVID-19-associated organ-specific cell types and cell-specific pathway cascade 443. Drug-induced cell viability prediction from LINCS-L1000 through WRFEN-XGBoost algorithm 444. MeSHHeading2vec: a new method for representing MeSH headings as vectors based on graph embedding algorithm 445. M6A2Target: a comprehensive database for targets of m6A writers, erasers and readers 446. Computational recognition of lncRNA signature of tumor-infiltrating B lymphocytes with potential implications in prognosis and immunotherapy of bladder cancer 447. MNDR v3. 0: mammal ncRNA–disease repository with increased coverage and annotation 448. CNA2Subpathway: identification of dysregulated subpathway driven by copy number alterations in cancer 449. DeepTorrent: a deep learning-based approach for predicting DNA N4-methylcytosine sites 450. Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection induces dysregulation of immunity: in silico gene expression analysis 451. A stack LSTM structure for decoding continuous force from local field potential signal of primary motor cortex (M1) 452. The Distinction of Omics in Amelioration of Food Crops Nutritional Value 453. DeepCNV: a deep learning approach for authenticating copy number variations 454. Key residues influencing binding affinities of 2019-nCoV with ACE2 in different species 455. A survey on computational models for predicting protein–protein interactions 456. ADeditome provides the genomic landscape of A-to-I RNA editing in Alzheimer’s disease 457. Integrated hybrid de novo assembly technologies to obtain high-quality pig genome using short and long reads 458. WIND (Workflow for pIRNAs aNd beyonD): a strategy for in-depth analysis of small RNA-seq data 459. Current Situation and Prospect of EMDB/EMPIAR-China 460. isomiRs–Hidden Soldiers in the miRNA Regulatory Army, and How to Find Them? 461. Identifying the natural polyphenol catechin as a multi-targeted agent against SARS-CoV-2 for the plausible therapy of COVID-19: an integrated computational … 462. rmvp: A memory-efficient, visualization-enhanced, and parallel-accelerated tool for genome-wide association study 463. Roles of host small RNAs in the evolution and host tropism of coronaviruses 464. CpG-island-based annotation and analysis of human housekeeping genes 465. Classification and gene selection of triple-negative breast cancer subtype embedding gene connectivity matrix in deep neural network 466. A novel privacy-preserving federated genome-wide association study framework and its application in identifying potential risk variants in ankylosing spondylitis 467. QAUST: Protein Function Prediction Using Structure Similarity, Protein Interaction, and Functional Motifs 468. Comparative host–pathogen protein–protein interaction analysis of recent coronavirus outbreaks and important host targets identification 469. Adult polyglucosan body disease—an atypical compound heterozygous with a novel GBE1 mutation 470. Differential expression of Triggering Receptor Expressed on Myeloid cells 2 (Trem2) in tissue eosinophils 471. Breast Tumor Microenvironment in Black Women: A Distinct Signature of CD8+ T Cell Exhaustion 472. MiBiOmics: An interactive web application for multi-omics data exploration and integration 473. Computational prediction and interpretation of both general and specific types of promoters in Escherichia coli by exploiting a stacked ensemble-learning framework 474. Development of a novel immune-related lncRNA signature as a prognostic classifier for endometrial carcinoma 475. SCDC: bulk gene expression deconvolution by multiple single-cell RNA sequencing references 476. MolAICal: a soft tool for 3D drug design of protein targets by artificial intelligence and classical algorithm 477. Homoeologous gene expression and co-expression network analyses and evolutionary inference in allopolyploids 478. Exosomal circRNA as a novel potential therapeutic target for multiple myeloma-related peripheral neuropathy 479. Predicting protein subchloroplast locations: the 10th anniversary 480. Tensor decomposition with relational constraints for predicting multiple types of microRNA-disease associations 481. GPS-Palm: a deep learning-based graphic presentation system for the prediction of S-palmitoylation sites in proteins 482. DSG2 expression is low in colon cancer and correlates with poor survival 483. Deep sparse transfer learning for remote smart tongue diagnosis [J] 484. A hybrid method for classification of physical action using discrete wavelet transform and artificial neural network 485. cncRNAdb: a manually curated resource of experimentally supported RNAs with both protein-coding and noncoding function 486. Design of an epitope-based peptide vaccine against the SARS-CoV-2: a vaccine-informatics approach 487. Upregulation of peroxisome proliferator-activated receptor-a and the lipid metabolism pathway promotes carcinogenesis of ampullary cancer 488. HISNAPI: a bioinformatic tool for dynamic hot spot analysis in nucleic acid–protein interface with a case study 489. Mesenchymal stromal cells provide hepatic support after extended hepatectomy by modulating thrombospondin-1/TGF-ß 490. PySmash: Python package and individual executable program for representative substructure generation and application 491. Exploring transcriptional switches from pairwise, temporal and population RNA-Seq data using deepTS 492. CAMAMED: a pipeline for composition-aware mapping-based analysis of metagenomic data 493. NCMCMDA: miRNA–disease association prediction through neighborhood constraint matrix completion 494. Allogeneic hematopoietic stem cell transplantation in leukocyte adhesion deficiency type I and III 495. Justification of the Choice of Signal Processing Method and Its Implementation in the Digital Part of the Receiver for Radar Stations 496. TRlnc: a comprehensive database for human transcriptional regulatory information of lncRNAs 497. Biomedical data and computational models for drug repositioning: a comprehensive review 498. ?????????????? 499. Comprehensive characterization of alternative splicing in renal cell carcinoma 500. Clinically relevant updates of the HbVar database of human hemoglobin variants and thalassemia mutations 501. Transcriptome analysis of cepharanthine against a SARS-CoV-2-related coronavirus 502. Toward a gold standard for benchmarking gene set enrichment analysis 503. Web-Based Base Editing Toolkits: BE-Designer and BE-Analyzer 504. Multigene editing: current approaches and beyond 505. Guía docente 200630-FBIO-Fundamentos de Bioinformática 506. Identification of Potential Gene and MicroRNA Biomarkers of Acute Kidney Injury 507. Further promotion of “the JSH plan for the future” conscious of new normal after/with COVID-19: message from the new president of the Japanese Society of … 508. Predicting drug-induced hepatotoxicity based on biological feature maps and diverse classification strategies 509. The international nucleotide sequence database collaboration 510. Integrating multi-network topology for gene function prediction using deep neural networks 511. PyConvU-Net: a lightweight and multiscale network for biomedical image segmentation 512. Recent advances in user-friendly computational tools to engineer protein function 513. Interpretable detection of novel human viruses from genome sequencing data 514. Comprehensive fundamental somatic variant calling and quality management strategies for human cancer genomes 515. DeepCPP: a deep neural network based on nucleotide bias information and minimum distribution similarity feature selection for RNA coding potential prediction 516. LncRNA LIFR-AS1 promotes proliferation and invasion of gastric cancer cell via miR-29a-3p/COL1A2 axis 517. Application of deep learning methods in biological networks 518. Molecular dynamics simulations for genetic interpretation in protein coding regions: where we are, where to go and when 519. Genome Resource: Ralstonia solanacearum Phylotype II Sequevar 1 (Race 3 Biovar 2) Strain UW848 From the 2020 US Geranium Introduction 520. Genome-wide expression profiling of long non-coding RNAs and competing endogenous RNA networks in alopecia areata [J] 521. Diagnostic and prognostic value of thymidylate synthase expression in breast cancer 522. The functional determinants in the organization of bacterial genomes 523. Inferring microenvironmental regulation of gene expression from single-cell RNA sequencing data using scMLnet with an application to COVID-19 524. From ArrayExpress to BioStudies 525. AntiCP 2.0: an updated model for predicting anticancer peptides 526. Exploration of natural compounds with anti-SARS-CoV-2 activity via inhibition of SARS-CoV-2 Mpro 527. The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring county-level vulnerability using visualization, statistical modeling, and machine … 528. How do we share data in COVID-19 research? A systematic review of COVID-19 datasets in PubMed Central Articles 529. Systemic effects of missense mutations on SARS-CoV-2 spike glycoprotein stability and receptor-binding affinity 530. Progress and challenge for computational quantification of tissue immune cells 531. Closing the circle: current state and perspectives of circular RNA databases 532. The Compensation of Radiation-Induced Losses in the Fiber Optic Communication Line in Its Operation Mode 533. A comprehensive integrated drug similarity resource for in-silico drug repositioning and beyond 534. A Comprehensive Analysis Identified Hub Genes and Associated Drugs in Alzheimer’s Disease 535. GENCODE 2021 536. Network analyses in microbiome based on high-throughput multi-omics data 537. Different molecular enumeration influences in deep learning: an example using aqueous solubility 538. Integrated omics analysis reveals the alteration of gut microbe–metabolites in obese adults 539. Archaeal roots of intramembrane aspartyl protease siblings signal peptide peptidase and presenilin 540. RICORD: A Precedent for Open AI in COVID-19 Image Analytics 541. A new graph-based clustering method with application to single-cell RNA-seq data from human pancreatic islets 542. Discovery of G-quadruplex-forming sequences in SARS-CoV-2 543. Algorithm optimization for weighted gene co-expression network analysis: accelerating the calculation of Topology Overlap Matrices with OpenMP and SQLite 544. Exploring associations of non-coding RNAs in human diseases via three-matrix factorization with hypergraph-regular terms on center kernel alignment 545. QSAR-assisted-MMPA to expand chemical transformation space for lead optimization 546. Regulatory Assessment of Off-Target Changes and Spurious DNA Insertions in Gene-Edited Organisms for Agri-Food Use 547. DNSS2: improved ab initio protein secondary structure prediction using advanced deep learning architectures 548. DPCMNE: detecting protein complexes from protein-protein interaction networks via multi-level network embedding 549. PanACoTA: A modular tool for massive microbial comparative genomics 550. Peptides: Molecular and Biotechnological Aspects. Biomolecules 2021, 11, 52

Research Topics Computer Science

Bioinformatics

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