Research Topics Molecular biology

Research Area/ Research Interest: Molecular biology

Research Paper Topics for Masters and Ph.D. Thesis and publication

  1. The 2022 Nucleic Acids Research database issue and the online molecular biology database collection
  2.  Contributions of molecular biology to antipsychotic drug discovery: promises fulfilled or unfulfilled?
  3. Recent Advances on Immunohistochemistry and Molecular Biology for the Diagnosis of Adnexal Sweat Gland Tumors
  4. History and current status of sugarcane breeding, germplasm development and molecular biology in India
  5.  Fleshing out the amyloid cascade hypothesis: the molecular biology of Alzheimer’s disease
  6. Biopesticides: a genetics, genomics, and molecular biology perspective
  7. Study on the mechanism of Yupingfeng powder in the treatment of immunosuppression based on UPLC⁃ QTOF⁃ MS, network pharmacology and molecular biology …
  8.  Two Different Types of Sarcoma Occurring Synchronously: The Impact of Molecular Biology on Therapeutic Strategy
  9. Basic Concepts of Molecular Biology
  10. Molecular Biology and Molecular Genetics
  11. Sporadic and Inherited Colorectal Cancer: How Epidemiology and Molecular Biology Guide Screening and Treatment
  12.  Exploration of Research-Based Classroom Teaching Model in the Teaching of Biochemistry and Molecular Biology
  13. Retrospective analysis of molecular biology mechanism of ABO blood group typing discrepancy among blood donors in Jinan blood station
  14.  Remembering Professor Krishna K. Tewari (1937–2017): A Pioneer in Plant Molecular Biology
  15. The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences
  16.  Undergraduate structural biology education: A shift from users to developers of computation and simulation tools
  17. InsectBase 2.0: a comprehensive gene resource for insects
  18. The IntAct database: efficient access to fine-grained molecular interaction data
  19. The Explorer’s Guide to Biology: a free multimedia educational resource to promote deep learning and understanding of the scientific process
  20. Cryo-EM in molecular and cellular biology
  21. ConsensusPathDB 2022: molecular interactions update as a resource for network biology
  22. … potentiates doxorubicin sensitivity in triple‐negative breast cancer cells by targeting MDR1 and JNK and suppressing mTOR and Bcl‐2: In vitro and molecular docking …
  23. Metabolomics-based molecular signatures reveal the toxic effect of co-exposure to nitrosamines in drinking water
  24.  Insect pests of potato: global perspectives on biology and management
  25. Molecular Biologic and Epidemiologic Insights for Preventability of Colorectal Cancer
  26. Molecular Basis of Breast Cancer
  27.  A paradigm shift in structural biology
  28. AMDB: a database of animal gut microbial communities with manually curated metadata
  29. RASCL: Rapid Assessment Of SARS-CoV-2 Clades Through Molecular Sequence Analysis
  30. Hypnea musciformis‐mediated Ag/AgCl‐NPs inhibit pathogenic bacteria, HCT‐116 and MCF‐7 cells’ growth in vitro and Ehrlich ascites carcinoma cells in vivo in …
  31. ORF19. 2286 Gene: Isolation and Purification of Deoxyhypusine Hydroxylase from the Human Pathogenic Yeast Candida albicans
  32. A rich and bountiful harvest: key discoveries in plant cell biology
  33. Keeping intracellular DNA untangled: A new role for condensin?
  34.  Structural Biology
  35. Back to the roots: A focus on plant cell biology
  36. Antiviral activity of esculin against white spot syndrome virus: A new starting point for prevention and control of white spot disease outbreaks in shrimp seedling culture
  37. Molecular Targeted Therapies: Time for a Paradigm Shift in Medulloblastoma Treatment?
  38. Low vitamin D status at admission as a risk factor for poor survival in hospitalized patients with COVID-19: an Italian retrospective study
  39. A system biology approach to determine therapeutic targets by identifying molecular mechanisms and key pathways for type 2 diabetes that are linked to the …
  40. Morphological and molecular characteristics of fungal species associated with crown rot of strawberry in South Korea
  41.  Evaluating the effects of sodium glucose co-transporter-2 inhibitors from a renin–angiotensin–aldosterone system perspective in patients infected with COVID …
  42. geneExpressionFromGEO: an R package to facilitate data reading from Gene Expression Omnibus (GEO)
  43. The genetic gods
  44. TLK1‐mediated MK5‐S354 phosphorylation drives prostate cancer cell motility and may signify distinct pathologies
  45. Highlight: Comparative Population Genomics—Answering Old Questions with New Data
  46. A new liposomal nanocarrier for co-delivery of gedunin and p-glycoprotein siRNA to target breast cancer stem cells
  47. A Powerful Method for Studying Protein–Protein Interactions in Plants: Coimmunoprecipitation (Co-IP) Assay
  48. Pyrosequencing Primer Design for Forensic Biology Applications
  49. Molecumentary: Adaptable Narrated Documentaries Using Molecular Visualization
  50. Chemical Calculation in the Laboratory
  51.  The biology of fear-and anxiety-related behaviors
  52.  Dept. of Molecular and Cell Biology University of California at Berkeley
  53. Building Structural Models of a Whole Mycoplasma Cell
  54. Disulfide bonds play a critical role in the structure and function of the receptor-binding domain of the SARS-CoV-2 spike antigen
  55. Evaluation of the antiapoptotic and anti-inflammatory properties of chitosan in methotrexate-induced oral mucositis in rats
  56. Comprehensive species sampling and sophisticated algorithmic approaches refute the monophyly of Arachnida
  57. Phylogenetic articulation of uric acid evolution in mammals and how it informs a therapeutic uricase
  58. Spectrum of HBB gene mutations among 696 β–thalassemia patients and carriers in Southern Vietnam
  59. Dynamics and conformational changes in human NEIL2 DNA glycosylase analyzed by hydrogen/deuterium exchange mass spectrometry
  60. Mitochondrial DNA Copy Number in Cleavage Stage Human Embryos—Impact on Infertility Outcome
  61. Divisão celular: modelização em Genética e Biologia Molecular
  62. RNAInter v4. 0: RNA interactome repository with redefined confidence scoring system and improved accessibility
  63. Vitamin D [25 (OH) D] metabolites and epimers in obese subject: interaction and correlations with adverse metabolic health risk factors
  64. Diagnostic, prognostic and therapeutic potential of long noncoding RNAs in cancer
  65. Epidemiological Study and Clinical Characteristics of Crohn’s Disease in The West Algerian Population
  66. Characterizing serotonin biosynthesis in Setaria viridis leaves and its effect on aphids
  67. Molecular ecology of a shallow water shrimp, Acetes sibogae sibogae Hansen 1919: Evidence for strongly limited gene flow across the western Pacific
  68. Green algae (Viridiplantae) in sediments from three lakes on Vega Island, Antarctica, assessed using DNA metabarcoding
  69. Chromosomal fusions facilitate adaptation to divergent environments in threespine stickleback
  70.  Ambystoma mexicanum, a model organism in developmental biology and regeneration: a colombian experience
  71. Antineoplastic effects of erufosine on small cell and non-small cell lung cancer cells through induction of apoptosis and cell cycle arrest
  72. CRISPR gene editing of major domestication traits accelerating breeding for Solanaceae crops improvement
  73. F-box only protein 9 and its role in cancer
  74. MicroRNAs as Indicators into the Causes and Consequences of Whole-Genome Duplication Events
  75. miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3尾
  76. Reference gene selection for quantitative RT-PCR in Miscanthus sacchariflorus under abiotic stress conditions
  77. The European Variation Archive: a FAIR resource of genomic variation for all species
  78.  Mosquito long non-coding RNAs are enriched with Transposable Elements
  79. Evolutionary Implications of the RNA N6-Methyladenosine Methylome in Plants
  80. Special Sections for the Inaugural Small Proteins, Big Questions Virtual Conference
  81. Dynamic development of AT‐rich heterochromatin has followed diversification and genome expansion of psammophilous Mycetophylax (Formicidae: Attini: Attina)
  82.  Characterization of Soybean Genotypes on the Basis of Yield Attributing Traits and SSR Molecular Markers
  83. Repositioning Ivermectin for Covid-19 treatment: Molecular mechanisms of action against SARS-CoV-2 replication
  84.  RNA sequencing and its applications in cancer and rare diseases
  85. An evaluation of hepatitis E virus molecular typing methods
  86. Plant Systems Biology: Lessons from Teaching
  87. The effects of glipizide on DNA damage and nuclear transport in differentiated 3T3-L1 adipocytes
  88.  Antibiotic resistance, biofilm production ability and genetic diversity of carbapenem-resistant Pseudomonas aeruginosa strains isolated from nosocomial …
  89. Thioredoxin-1 inhibits amyloid-β25–35-induced activation of NLRP1/caspase-1/GSDMD pyroptotic pathway in PC12 cells
  90. The diverse functions of small heat shock proteins in the proteostasis network
  91. VannoPortal: multiscale functional annotation of human genetic variants for interrogating molecular mechanism of traits and diseases
  92. Mitogenome of Knodus borki (Cypriniformes: Characidae): genomic characterization and phylogenetic analysis
  93.  Blocking TNF signaling may save lives in COVID-19 infection
  94. ReMap 2022: a database of Human, Mouse, Drosophila and Arabidopsis regulatory regions from an integrative analysis of DNA-binding sequencing experiments
  95. Immunotherapeutic role of cabazitaxel treatment in the activation of TLR3 signalling in metastatic castration-resistant prostate cancer in vitro
  96. EVAtlas: a comprehensive database for ncRNA expression in human extracellular vesicles
  97. Do we have infraspecific taxa of Salvia macrosiphon Boiss.(Lamiaceae) in Iran?
  98. Proteasome inhibitor immunotherapy for the epithelial to mesenchymal transition: assessing the A549 lung cancer cell microenvironment and the role of M1, M2a and …
  99. Nanoliposomal formulation of pistachio hull extract: preparation, characterization and anti-cancer evaluation through Bax/Bcl2 modulation
  100. Establishing a Lipid Bilayer for Molecular Dynamics Simulations
  101. Systems biology–the transformative approach to integrate sciences across disciplines
  102. The centrality of evolution in biology teaching: towards a pluralistic perspective
  103.  Molecular and functional characterization of a SCD 1b from European sea bass (Dicentrarchus labrax L.)
  104. scEnhancer: a single-cell enhancer resource with annotation across hundreds of tissue/cell types in three species
  105. Structural determination of model phospholipid membranes by Raman spectroscopy: Laboratory experiment
  106.  Plasma oxyphytosterols most likely originate from hepatic oxidation and subsequent spill-over in the circulation
  107.  New Progress in Clinical Diagnosis, Treatment and Laboratory Testing of Acute Respiratory Infections in Children
  108. Differentially methylation of IFI44L gene promoter in Iranian patients with systemic lupus erythematosus and rheumatoid arthritis
  109.  NATURAL PRODUCTS WITH ANTICANCER ACTIVITY: A REVIEW OF IN VITRO, IN VIVO AND MOLECULAR DOCKING ASSAYS
  110. Beneficial Effects of a Combination of Curcuma longa L. and Citrus junos Against Beta-Amyloid Peptide-Induced Neurodegeneration in Mice
  111. Draft Genome Sequences of Nine Bacillus Strains and Two Weizmannia Strains Isolated from Live Dietary Supplements and a Cultured Food Product
  112. Refget: standardized access to reference sequences
  113. The Natural Products Atlas 2.0: a database of microbially-derived natural products
  114. Genomicus in 2022: comparative tools for thousands of genomes and reconstructed ancestors
  115. Essays on the Anthropology of Reason
  116. 3DSNP 2.0: update and expansion of the noncoding genomic variant annotation database
  117. Trichostatin A inhibits dendritic cell maturation through down-regulating NF—κ B (p65) pathway
  118. Curcumin sensitizes carboplatin treatment in triple negative breast cancer through reactive oxygen species induced DNA repair pathway
  119. Evidence of a shared binding site for Bacillus thuringiensis Cry1Ac and Cry2Aa toxins in Cnaphalocrocis medinalis cadherin
  120. Bioactive components to inhibit foam cell formation in atherosclerosis
  121.  Diversity of bacteriocins in the microbiome of the Tucuruí Hydroelectric Power Plant water reservoir and three-dimensional structure prediction of a zoocin
  122. Emerging bioelectronics for brain organoid electrophysiology
  123.  Assessment of genotyping markers in the molecular characterization of a population of clinical isolates of Fusarium in Colombia
  124. A tissue perfusion harvest model for optimal multisystem comparisons of pathobiology
  125. Comparative gene expression study highlights molecular similarities between triple negative breast cancer tumours and feline mammary carcinomas
  126. Organotypic and Microphysiological Human Tissue Models for Drug Discovery and Development—Current State-of-the-Art and Future Perspectives
  127. TRIP13 knockdown inhibits the proliferation, migration, invasion, and promotes apoptosis by suppressing PI3K/AKT signaling pathway in U2OS cells
  128. Applications of genetic code expansion in studying protein post-translational modification
  129. New update on molecular diversity of clinical Staphylococcus aureus isolates in Iran: antimicrobial resistance, adhesion and virulence factors, biofilm formation and …
  130. DOP47 Identification and characterization of T-cell receptor sequences associated with Crohn’s Disease
  131. Amplicon remodeling and genomic mutations drive population dynamics after segmental amplification
  132. Co-evolutionary Signals Identify Burkholderia pseudomallei Survival Strategies in a Hostile Environment
  133. Potassium at the Origins of Life: Did Biology Emerge From Biotite in Micaceous Clay?
  134. Prediction of disordered regions in proteins with recurrent neural networks and protein dynamics
  135. Mechanisms of Antiviral Immune Evasion of SARS-CoV-2
  136. Two trehalase isoforms, produced from a single transcript, regulate drought stress tolerance in Arabidopsis thaliana
  137. The two non-visual arrestins engage ERK2 differently
  138. Beneficial effects of MgSO4 on TFAM, UPC3 and FNDC5 mRNA expressions in skeletal muscle of type 2 diabetic rats: a possible mechanism to improve insulin …
  139. dNTPpoolDB: a manually curated database of experimentally determined dNTP pools and pool changes in biological samples
  140. The columbamine O-methyltransferase gene (CoOMT) is capable of increasing alkaloid content in transgenic tobacco plants
  141. Structure of a Cell Entry Defective Human Adenovirus Provides Insights into Precursor Proteins and Capsid Maturation
  142. Nuclear protein condensates and their properties in regulation of gene expression
  143. Gasdermin and gasdermin-like pore-forming proteins in invertebrates, fungi and bacteria
  144. Into the second decade
  145. Limited introgression between rock-wallabies with extensive chromosomal rearrangements
  146. findMySequence: a neural-network-based approach for identification of unknown proteins in X-ray crystallography and cryo-EM
  147. Structural basis of the selective sugar transport in sodium-glucose cotransporters
  148. The role of FOXC1/FOXCUT/DANCR axis in triple negative breast cancer: a bioinformatics and experimental approach
  149.  CNOT7 outcompetes its paralog CNOT8 for integration into the CCR4-NOT complex
  150. Isopimpinellin extends antiangiogenic effect through overexpression of miR-15b-5p and downregulating angiogenic stimulators
  151. Alteration of miR-362-5p and miR-454-3p expression elicits diverse responses in breast cancer cell lines
  152. Diagnosis, risk factors analysis and first molecular characterization of Cryptosporidium spp. in horses from Rio de Janeiro, Brazil
  153. Structural basis for blocked excited state proton transfer in a fluorescent, photoacidic non-canonical amino acid-containing antibody fragment
  154.  Chromosomal diversity in three species of Lycosa Latreille, 1804 (Araneae, Lycosidae): Inferences on diversification of diploid number and sexual …
  155. Phylogeography reveals association between swine trade and the spread of porcine epidemic diarrhea virus in China and across the world
  156. Meet the Editorial Board Member
  157. Correction for Chan et al.,“A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge”
  158. Butyrate Production Pathway Abundances Are Similar in Human and Nonhuman Primate Gut Microbiomes
  159. Molecular Cloning and Analysis of CpDHN1, a Gene in Response to Drought Stress in Papay
  160. Antifungal Studies of Alkaloids and Flavonoids of Asparagus albus from the Arid Region of Algeria
  161. Cell scientist to watch–Martin Loose
  162. Phosphoregulation of the autophagy machinery by kinases and phosphatases
  163. Histone H3 Inhibits Ubiquitin-Ubiquitin Intermolecular Interactions to Enhance Binding to DNA Methyl Transferase 1
  164.  Ready and Waiting: Where Early-Stage Idiopathic Pulmonary Fibrosis Fibroblasts Are Primed to Be Activated
  165. SAbDab in the age of biotherapeutics: updates including SAbDab-nano, the nanobody structure tracker
  166. The Neighborhood of the Spike Gene Is a Hotspot for Modular Intertypic Homologous and Nonhomologous Recombination in Coronavirus Genomes
  167. The RabGAPs EPI64A and EPI64B regulate the apical structure of epithelial cells †
  168. Genomic signatures of recent adaptation in a wild bumblebee
  169.  Bioinformatics: Methods and Applications-Genomics, Proteomics and Drug Discovery
  170. New Insight into the Pigment Composition and Molecular Mechanism of Flower Coloration in Tulip (Tulipa gesneriana L.) Cultivars with Various Petal Colors
  171. Exploring the genetic potential of Pakistani soybean cultivars through RNA-seq based transcriptome analysis
  172. PANoptosis in viral infection: the missing puzzle piece in the cell death field
  173. Molecular modeling, docking and dynamic simulations of growth hormone receptor (GHR) of Labeo rohita
  174. Development of the DNA-based biosensors for high performance in detection of molecular biomarkers: More rapid, sensitive, and universal
  175. The importance of avian physiology
  176. Characterization of White Button Mushroom and Its Biomedical Applications
  177. Exploring of bacterial blight resistance in landraces and mining of resistant gene (s) using molecular markers and pathogenicity approach
  178. Structural insights into the catalytic cycle of a bacterial multidrug ABC efflux pump
  179. SHOX2 methylation in Vietnamese patients with lung cancer
  180. Expression of Concern for Kim et al., “Complete Sequence of blaKPC-2-Harboring Plasmid with a Mosaic of IncN1- and IncN3-Type Plasmids in a Klebsiella …
  181. Regeneration Roadmap: database resources for regenerative biology
  182. Modeling sequence-space exploration and emergence of epistatic signals in protein evolution
  183. Structural and Functional Characterization of a Biliverdin-Binding Near-Infrared Fluorescent Protein From the Serpin Superfamily
  184. Range extension and species confirmation of Rhyneptesicus nasutus (Sind Serotine Bat)(Mammalia: Chiroptera) from Bajaur Agency, FATA, Pakistan
  185. Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair
  186. Molecular characterization and structural dynamics of Aquaporin1 from walking catfish in lipid bilayers
  187. Metabolomic profiling of stool of two‐year old children from the INSIGHT study reveals links between butyrate and child weight outcomes
  188. RECOMB 2021 Special Issue
  189. Resveratrol: A Potential Protector Against Benzo [a] pyrene-Induced Lung Toxicity.
  190. 45S rDNA Repeats of Turtles and Crocodiles Harbor a Functional 5S rRNA Gene Specifically Expressed in Oocytes
  191. Converting a formerly in‐person biochemistry course based undergraduate research experience to online teaching during the COVID‐19 pandemic
  192. Joint inference of migration and reassortment patterns for viruses with segmented genomes
  193. Dead-end hybridization in walnut trees revealed by large-scale genomic sequence data
  194. Tightly constrained genome reduction and relaxation of purifying selection during secondary plastid endosymbiosis
  195. Construction and Analysis of a Yeast cDNA Library from Medicago truncatula
  196. New data on Henneguya postexilis Minchew, 1977, a parasite of channel catfish Ictalurus punctatus, with notes on resolution of molecular markers for myxozoan …
  197.  The Rad5 helicase and RING domains contribute to genome stability through their independent catalytic activities
  198. TikTok: an emergent opportunity for teaching and learning science communication online
  199.  Beyond RuBisCO: Convergent molecular evolution of multiple chloroplast genes in C4 plants
  200. vcf2gwas: Python API for comprehensive GWAS analysis using GEMMA
  201. “Half-wet-half-dry”: an innovation in undergraduate laboratory classes to generate transgenic mouse models using CRISPR/Cas9 and computer simulation
  202. Variation in copper sensitivity between laboratory and wild strains of Caenorhabditis elegans
  203. Genome survey of Misgurnus anguillicaudatus to identify genomic information, simple sequence repeat (SSR) markers, and mitochondrial genome
  204. Modeling Developmental Brain Diseases Using Human Pluripotent Stem Cells-Derived Brain Organoids–Progress and Perspective
  205. How the Brain Works: LTP, NMDA, and NO
  206.  Role and relevance of fish cell lines in advanced in vitro research
  207. Methods to Assess Oxidative DNA Base Damage Repair of Apurinic/Apyrimidinic (AP) Sites Using Radioactive and Nonradioactive Oligonucleotide-Based Assays
  208. Modular Evolution of the Drosophila Metabolome
  209. Targeting the 3CLpro and RdRp of SARS-CoV-2 with phytochemicals from medicinal plants of the Andean Region: molecular docking and molecular dynamics …
  210.  Translation initiation from sequence variants of the bacteriophage T7 g10RBS in Escherichia coli and Agrobacterium fabrum
  211.  Determination of Genetic Diversity and Screening of BCMV and BCMNV Resistance in Some Bean Genotypes Using Molecular Markers
  212. Genome-wide reconstruction of rediploidization following autopolyploidization across one hundred million years of salmonid evolution
  213. TomoFlow: Analysis of continuous conformational variability of macromolecules in cryogenic subtomograms based on 3D dense optical flow
  214.  The effect of a static magnetic field and baicalin or baicalein interactions on amelanotic melanoma cell cultures (C32)
  215. Clustering Methods for Microarray Data Sets
  216. The European Genome-phenome Archive in 2021
  217. Higher classification of mealybugs (Hemiptera: Coccomorpha) inferred from molecular phylogeny and their endosymbionts
  218. Cancer Immuno-prevention
  219. The potential role of procyanidin as a therapeutic agent against SARS-CoV-2: a text mining, molecular docking and molecular dynamics simulation approach
  220. Psoralidin exerts anti-tumor, anti-angiogenic, and immunostimulatory activities in 4T1 tumor‐bearing balb/c mice
  221. Molecular ecology of plant volatiles in interactions with insect herbivores
  222.  Genome survey sequencing of common vetch (Vicia sativa L.) and genetic diversity analysis of Chinese germplasm with genomic SSR markers
  223. ASMdb: a comprehensive database for allele-specific DNA methylation in diverse organisms
  224. Anti-inflammatory cytokines in sickle cell disease
  225. Analysis of senescence-responsive stress fiber proteome reveals reorganization of stress fibers mediated by elongation factor eEF2 in HFF-1 cells
  226. Dynamic RNA fitness landscapes of a group I ribozyme during changes to the experimental environment
  227. Potent inhibition of TCP transcription factors by miR319 ensures proper root growth in Arabidopsis
  228. NPCDR: natural product-based drug combination and its disease-specific molecular regulation
  229. OncoSplicing: an updated database for clinically relevant alternative splicing in 33 human cancers

 

Research Topics Biology

Prof.Fazal Rehman Shamil (Available for Professional Discussions)
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