Set of Important MCQs onĀ Metabolism of Carbohydrates for the preparation of tests for chemistry and biology.Ā
The key coenzyme for the activity of muscle glycogen phosphorylase is-
- Cyclic AMP
- NAD
- Pyridoxal phosphate
- Coenzyme A
Question Answer: Pyridoxal phosphate
Pyruvate is accumulated in case of the dietary deficiency of vitamin.
- Thiamine
- Folic acid
- Cobalamine
- Pyridoxine
Question Answer: Thiamine
Which is correct regarding gluconeogenesis?
- In mammals, gluconeogenesis occurs predominantly in the liver
- It converts glucose to glycogen
- It is glycolysis running in opposite direction
- Plants do not undertake gluconeogenesis
Question Answer: In mammals, gluconeogenesis occurs predominantly in the liver
Which can be synthesized from pyruvate?
- Acetyl CoA
- Lactic acid
- Ethanol
- Both A, B, and C
Question Answer: Both A, B, and C
Glucose 1, 6-Bisphosphate is intermediate in _______.
- Glycolytic pathway
- Gluconeogenesis pathway
- Phosphoglucomutase reaction
- Glycogen synthetic pathway
Question Answer: Phosphoglucomutase reaction
Glucose yields how many ATPs by Glycolysis?
- 8
- 11
- 5
- 10
Question Answer: 8
The most important regulatory step in glycolysis is:
- Formation of fructose-1,6- diphosphate
- Formation of glucose-6-phosphate
- Formation of fructose-6-phosphate
- Formation of glyceraldehydes-3- phosphate
Question Answer: Formation of fructose-1,6- diphosphate
Which of the following is the pathway of conversion of glucose to glycogen?
- Glycolysis
- Glycogenolysis
- Glycogenesis
- Gluconeogenesis
Question Answer: Glycogenesis
Which is correct regarding pyruvate dehydrogenase enzyme?
- It converts pyruvate to oxaloacetate
- It catalyzes oxidative decarboxylation reaction.
- it is localized in the cytosol eukaryotic cells
- It requires NADH
Question Answer: It catalyzes oxidative decarboxylation reaction
The citric acid cycle is amphibolic pathway, and it can be referred as _____
- It is linked to other cycles
- It serves in both anabolic and catabolic processes
- It can catalyze reactions that are both exergonic and endergonic
- It can move in both forward and reverse directions
Question Answer: It serves in both anabolic and catabolic processes
In Which forms is glucose liberated from glycogen?
- Glucose-1-Phosphate
- Glucose-6-Phosphate
- UDP-glucose
- Both A, B, and C
Question Answer: Glucose-1-Phosphate
The first reaction in citric acid cycle is _______, which generates citrate.
- A condensation reaction
- An oxidative decarboxylation reaction
- Dehydrogenation reaction
- A dehydration reaction
Question Answer: A condensation reaction
Which is correct regarding all the dehydrogenase enzymes that participate in the citric acid cycle?
- They catalyze condensation reactions
- They generate COā
- They convert a single bond to a double bond
- They generate reduced electron carriers
Question Answer: They generate reduced electron carriers
What role does the coenzyme A play in the citric acid cycle?
- It is an acyl group carrier
- It carries hydride ions
- It is an electron carrier
- It is an oxidizing agent
Question Answer: It is an acyl group carrier
Skeletal muscle does not contribute glucose to blood because:
- It lacks the enzyme glycogen phosphorylase
- It cannot store glycogen
- It lacks the enzyme glucose-6-phosphatase
- It lacks the enzyme Phosphoglucomutase
Question Answer: It lacks the enzyme glucose-6-phosphatase
Under which conditions would lactic acid accumulate in skeletal muscle?
- When citric acid enzymes are depleted
- When O2 is depleted
- When ATP is depleted
- When NADH is depleted
Question Answer: When O2 is depleted
Which processes does not generate CO2?
- Citric acid Cycle
- Conversion of Pyruvate to Lactate
- Conversion of Pyruvate to Acetyl CoA
- Conversion of Pyruvate to ethanol
Question Answer: Conversion of Pyruvate to Lactate
18 A metabolically active cell is in a steady state only if:
- The rate of metabolic flow is unchanged
- Intermediates are formed and consumed at equal at equal rates
- There is no flux
- It is at equilibrium with its surroundings
Question Answer: Intermediates are formed and consumed at equal at equal rates
What is the net yield of NADH when 1 mole of glucose-6-phosphate is oxidized by aerobic glycolysis to yield pyruvate?
- 2 mole
- 1 mole
- 0 mole
- 4 mole
Question Answer: 2 mole
For every molecule of glucose, how many molecules of CO are released in the citric acid cycle?
- Four
- Two
- One
- Six
Question Answer: Four
Amino acids, fatty acids and glucose are oxidized and enter the citric acid cycle as:
- Pyruvate
- Acetate
- Acetyl-CoA
- Oxaloacetate
Question Answer: Acetyl-CoA
Sugar absorption from the intestine involves:
- Active transport
- Sodium lons
- Na-K ATPase
- Both A, B, and C
Question Answer: Both A, B, and C
What is the intracellular site for the operation of glycolysis?
- Cytosol
- Lysosomes
- Endoplasmic reticulum
- Mitochondria
Question Answer: Cytosol
What is another name for Glucokinase?
- Hexokinase IV
- Hexokinase II
- Hexokinase III
- Hexokinase I
Question Answer: Hexokinase IV
Fructokinase is present in which of the tissues?
- Heart
- Adipose tissue
- Liver
- Brain
Question Answer: Liver
Which is correct regarding the inter-conversion of nutrients?
- Lipids can be converted to amino acids.
- Amino acids can be converted to glucose and lipids.
- Lipids can be converted to glucose.
- Both A, B, and C
Question Answer: Amino acids can be converted to glucose and lipids
Which can be said to act as a carrier of Citric acid cycle?
- Acetyl CoA
- Ketoglutarate
- Oxaloacetate
- Malate
Question Answer: Oxaloacetate
Salivary amylase is activated by
- Na
- CI
- HCO
- K
Question Answer: CI
Which statement is correct regarding the conversion of Pyruvate to Acetyl-CoA and CO2?
- It reversible
- Requires Lipoic Acid
- Occurs in the cytosol
- Both A, B, and C
Question Answer: Requires Lipoic Acid
The pentose phosphate pathway serves as a source for each of the following except:
- Ribose-5-phosphate
- NADPH
- ATP
- 6-phosphogluconic acid
Question Answer: ATP
Glycogen in muscle serves as _____.
- a source of fuel for ATP synthesis within that tissue
- primarily as a buffer of blood glucose levels
- a source of blood glucose after phosphatase action on Glu-6-p
- is rapidly synthesized during fasting
Question Answer: Serves as a source of fuel for ATP synthesis within that tissue
Glycolysis of Glucose, under anaerobic conditions, yields how many ATPS?
- 6
- 2
- 8
- 10
Question Answer: 2
Glucose-6-phosphatase is absent from Which tissues
- Kidney
- Intestine
- Brain
- Heart
Question Answer: Brain
What is common between Glycolysis and Pentose phosphate pathways?
- Both generate NADPH
- Both involve the oxidation of glucose
- Both generate ATP
- Formation of glyceraldehydes-3. Phosphate
Question Answer: Both involve the oxidation of glucose
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- Metabolism of Carbohydrates MCQs
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