Bone Metabolism Disorders MCQs

By: Prof. Dr. Fazal Rehman Shamil | Last updated: September 28, 2024

What is the primary hormone responsible for increasing blood calcium levels?
a) Calcitonin
b) Parathyroid hormone
c) Insulin
d) Estrogen
Answer: b) Parathyroid hormone

Which condition is characterized by low bone mass and deterioration of bone tissue?
a) Osteoporosis
b) Osteoarthritis
c) Osteosarcoma
d) Osteogenesis imperfecta
Answer: a) Osteoporosis

What is a common cause of secondary osteoporosis?
a) Aging
b) Hyperthyroidism
c) Genetic factors
d) Physical activity
Answer: b) Hyperthyroidism

What vitamin deficiency is primarily associated with osteomalacia?
a) Vitamin A
b) Vitamin B12
c) Vitamin D
d) Vitamin C
Answer: c) Vitamin D

What is the term for a genetic disorder characterized by brittle bones?
a) Osteoporosis
b) Osteogenesis imperfecta
c) Osteomalacia
d) Paget’s disease
Answer: b) Osteogenesis imperfecta

Which condition involves the abnormal remodeling of bone, leading to enlarged and weakened bones?
a) Osteomalacia
b) Paget’s disease
c) Osteoporosis
d) Osteosarcoma
Answer: b) Paget’s disease

What is the main mineral found in bones?
a) Sodium
b) Calcium
c) Magnesium
d) Iron
Answer: b) Calcium

What test is commonly used to assess bone mineral density?
a) MRI
b) X-ray
c) CT scan
d) DEXA scan
Answer: d) DEXA scan

What dietary element is crucial for maintaining healthy bone metabolism?
a) Phosphorus
b) Potassium
c) Iron
d) Sodium
Answer: a) Phosphorus

Which hormone plays a role in decreasing blood calcium levels?
a) Parathyroid hormone
b) Thyroid hormone
c) Calcitonin
d) Growth hormone
Answer: c) Calcitonin

What is the primary risk factor for developing osteoporosis?
a) Regular exercise
b) Female gender
c) Adequate calcium intake
d) Young age
Answer: b) Female gender

Which condition is characterized by a decrease in bone density and increased risk of fractures?
a) Osteoporosis
b) Osteoarthritis
c) Osteomalacia
d) Osteomyelitis
Answer: a) Osteoporosis

What is a common symptom of osteomalacia?
a) Joint swelling
b) Bone pain
c) Increased mobility
d) Muscle hypertrophy
Answer: b) Bone pain

Which of the following can lead to osteoporosis?
a) Excessive physical activity
b) Smoking
c) Adequate calcium intake
d) Regular weight-bearing exercise
Answer: b) Smoking

What is a common diagnostic tool for detecting Paget’s disease?
a) Bone scan
b) Ultrasound
c) Blood test
d) X-ray
Answer: d) X-ray

Which medication class is often used to treat osteoporosis?
a) Antidepressants
b) Bisphosphonates
c) Antibiotics
d) NSAIDs
Answer: b) Bisphosphonates

What condition is characterized by excessive calcium in the blood?
a) Hypocalcemia
b) Osteopenia
c) Hypercalcemia
d) Osteomalacia
Answer: c) Hypercalcemia

What is the most common cause of osteonecrosis?
a) Infection
b) Lack of blood supply
c) Inflammation
d) Vitamin D deficiency
Answer: b) Lack of blood supply

Which condition is associated with excessive bone resorption?
a) Osteosarcoma
b) Osteoporosis
c) Paget’s disease
d) Osteomalacia
Answer: b) Osteoporosis

What is the role of osteoblasts in bone metabolism?
a) Bone resorption
b) Bone formation
c) Bone remodeling
d) Bone repair
Answer: b) Bone formation

Which vitamin is essential for calcium absorption in the intestine?
a) Vitamin A
b) Vitamin C
c) Vitamin D
d) Vitamin K
Answer: c) Vitamin D

What is the primary effect of parathyroid hormone on bone?
a) Stimulates bone formation
b) Inhibits bone resorption
c) Stimulates bone resorption
d) Inhibits calcium absorption
Answer: c) Stimulates bone resorption

Which type of fracture is common in individuals with osteoporosis?
a) Greenstick fracture
b) Comminuted fracture
c) Compression fracture
d) Spiral fracture
Answer: c) Compression fracture

What is the most common site for osteoporotic fractures?
a) Wrist
b) Hip
c) Spine
d) Shoulder
Answer: c) Spine

What is a common treatment for osteogenesis imperfecta?
a) Surgery to fix fractures
b) Bisphosphonate therapy
c) Physical therapy
d) Vitamin D supplements
Answer: b) Bisphosphonate therapy

What is the hallmark sign of Paget’s disease on X-ray?
a) Osteophyte formation
b) Bone enlargement
c) Fracture lines
d) Cystic lesions
Answer: b) Bone enlargement

What dietary change can help prevent osteoporosis?
a) Decreasing calcium intake
b) Increasing caffeine intake
c) Increasing calcium and vitamin D intake
d) Reducing protein intake
Answer: c) Increasing calcium and vitamin D intake

Which population is most at risk for developing osteomalacia?
a) Young athletes
b) Pregnant women
c) Elderly individuals
d) Children
Answer: c) Elderly individuals

What is the main cause of hyperparathyroidism?
a) Vitamin D deficiency
b) Tumors of the parathyroid glands
c) Aging
d) Chronic kidney disease
Answer: b) Tumors of the parathyroid glands

Which of the following is a characteristic feature of osteoporosis?
a) High bone density
b) Increased bone fragility
c) Thickened bone cortex
d) Formation of osteophytes
Answer: b) Increased bone fragility

What role does estrogen play in bone metabolism?
a) Increases bone resorption
b) Promotes bone formation
c) Decreases calcium absorption
d) Inhibits bone formation
Answer: b) Promotes bone formation

Which of the following is a potential consequence of untreated osteoporosis?
a) Joint replacement
b) Increased flexibility
c) Fractures
d) Enhanced mobility
Answer: c) Fractures

What is the relationship between vitamin D and calcium?
a) Vitamin D decreases calcium absorption
b) Vitamin D is not related to calcium
c) Vitamin D increases calcium absorption
d) Calcium decreases vitamin D levels
Answer: c) Vitamin D increases calcium absorption

Which imaging technique is best for assessing bone metabolism disorders?
a) MRI
b) X-ray
c) CT scan
d) Bone scan
Answer: d) Bone scan

What can be a result of excessive alcohol consumption on bone health?
a) Increased bone density
b) Decreased bone formation
c) Enhanced calcium absorption
d) Improved overall health
Answer: b) Decreased bone formation

What is the effect of glucocorticoids on bone health?
a) Increase bone formation
b) Inhibit bone resorption
c) Cause bone loss
d) Improve calcium absorption
Answer: c) Cause bone loss

Which lifestyle factor is crucial for maintaining bone health?
a) Sedentary lifestyle
b) Adequate physical activity
c) High-sugar diet
d) Low-protein intake
Answer: b) Adequate physical activity

What condition results from a lack of adequate vitamin D during childhood?
a) Osteoporosis
b) Rickets
c) Osteogenesis imperfecta
d) Osteoarthritis
Answer: b) Rickets

What is the primary function of osteoclasts in bone metabolism?
a) Bone formation
b) Bone resorption
c) Bone repair
d) Bone remodeling
Answer: b) Bone resorption

Which of the following can indicate an underlying metabolic bone disorder?
a) Joint pain
b) Fractures with minimal trauma
c) Muscle cramps
d) Skin rashes
Answer: b) Fractures with minimal trauma

 

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