ย Bone Metabolism Disorders MCQs

By: Prof. Dr. Fazal Rehman | Last updated: September 28, 2024

What is the primary hormone responsible for increasing blood calcium levels? a) Calcitonin b) Parathyroid hormone c) Insulin d) Estrogen Answer: b) Parathyroid hormone Which condition is characterized by low bone mass and deterioration of bone tissue? a) Osteoporosis b) Osteoarthritis c) Osteosarcoma d) Osteogenesis imperfecta Answer: a) Osteoporosis What is a common cause of secondary osteoporosis? a) Aging b) Hyperthyroidism c) Genetic factors d) Physical activity Answer: b) Hyperthyroidism What vitamin deficiency is primarily associated with osteomalacia? a) Vitamin A b) Vitamin B12 c) Vitamin D d) Vitamin C Answer: c) Vitamin D What is the term for a genetic disorder characterized by brittle bones? a) Osteoporosis b) Osteogenesis imperfecta c) Osteomalacia d) Paget’s disease Answer: b) Osteogenesis imperfecta Which condition involves the abnormal remodeling of bone, leading to enlarged and weakened bones? a) Osteomalacia b) Paget’s disease c) Osteoporosis d) Osteosarcoma Answer: b) Paget’s disease What is the main mineral found in bones? a) Sodium b) Calcium c) Magnesium d) Iron Answer: b) Calcium What test is commonly used to assess bone mineral density? a) MRI b) X-ray c) CT scan d) DEXA scan Answer: d) DEXA scan What dietary element is crucial for maintaining healthy bone metabolism? a) Phosphorus b) Potassium c) Iron d) Sodium Answer: a) Phosphorus Which hormone plays a role in decreasing blood calcium levels? a) Parathyroid hormone b) Thyroid hormone c) Calcitonin d) Growth hormone Answer: c) Calcitonin What is the primary risk factor for developing osteoporosis? a) Regular exercise b) Female gender c) Adequate calcium intake d) Young age Answer: b) Female gender Which condition is characterized by a decrease in bone density and increased risk of fractures? a) Osteoporosis b) Osteoarthritis c) Osteomalacia d) Osteomyelitis Answer: a) Osteoporosis What is a common symptom of osteomalacia? a) Joint swelling b) Bone pain c) Increased mobility d) Muscle hypertrophy Answer: b) Bone pain Which of the following can lead to osteoporosis? a) Excessive physical activity b) Smoking c) Adequate calcium intake d) Regular weight-bearing exercise Answer: b) Smoking What is a common diagnostic tool for detecting Paget’s disease? a) Bone scan b) Ultrasound c) Blood test d) X-ray Answer: d) X-ray Which medication class is often used to treat osteoporosis? a) Antidepressants b) Bisphosphonates c) Antibiotics d) NSAIDs Answer: b) Bisphosphonates What condition is characterized by excessive calcium in the blood? a) Hypocalcemia b) Osteopenia c) Hypercalcemia d) Osteomalacia Answer: c) Hypercalcemia What is the most common cause of osteonecrosis? a) Infection b) Lack of blood supply c) Inflammation d) Vitamin D deficiency Answer: b) Lack of blood supply Which condition is associated with excessive bone resorption? a) Osteosarcoma b) Osteoporosis c) Paget’s disease d) Osteomalacia Answer: b) Osteoporosis What is the role of osteoblasts in bone metabolism? a) Bone resorption b) Bone formation c) Bone remodeling d) Bone repair Answer: b) Bone formation Which vitamin is essential for calcium absorption in the intestine? a) Vitamin A b) Vitamin C c) Vitamin D d) Vitamin K Answer: c) Vitamin D What is the primary effect of parathyroid hormone on bone? a) Stimulates bone formation b) Inhibits bone resorption c) Stimulates bone resorption d) Inhibits calcium absorption Answer: c) Stimulates bone resorption Which type of fracture is common in individuals with osteoporosis? a) Greenstick fracture b) Comminuted fracture c) Compression fracture d) Spiral fracture Answer: c) Compression fracture What is the most common site for osteoporotic fractures? a) Wrist b) Hip c) Spine d) Shoulder Answer: c) Spine What is a common treatment for osteogenesis imperfecta? a) Surgery to fix fractures b) Bisphosphonate therapy c) Physical therapy d) Vitamin D supplements Answer: b) Bisphosphonate therapy What is the hallmark sign of Paget’s disease on X-ray? a) Osteophyte formation b) Bone enlargement c) Fracture lines d) Cystic lesions Answer: b) Bone enlargement What dietary change can help prevent osteoporosis? a) Decreasing calcium intake b) Increasing caffeine intake c) Increasing calcium and vitamin D intake d) Reducing protein intake Answer: c) Increasing calcium and vitamin D intake Which population is most at risk for developing osteomalacia? a) Young athletes b) Pregnant women c) Elderly individuals d) Children Answer: c) Elderly individuals What is the main cause of hyperparathyroidism? a) Vitamin D deficiency b) Tumors of the parathyroid glands c) Aging d) Chronic kidney disease Answer: b) Tumors of the parathyroid glands Which of the following is a characteristic feature of osteoporosis? a) High bone density b) Increased bone fragility c) Thickened bone cortex d) Formation of osteophytes Answer: b) Increased bone fragility What role does estrogen play in bone metabolism? a) Increases bone resorption b) Promotes bone formation c) Decreases calcium absorption d) Inhibits bone formation Answer: b) Promotes bone formation Which of the following is a potential consequence of untreated osteoporosis? a) Joint replacement b) Increased flexibility c) Fractures d) Enhanced mobility Answer: c) Fractures What is the relationship between vitamin D and calcium? a) Vitamin D decreases calcium absorption b) Vitamin D is not related to calcium c) Vitamin D increases calcium absorption d) Calcium decreases vitamin D levels Answer: c) Vitamin D increases calcium absorption Which imaging technique is best for assessing bone metabolism disorders? a) MRI b) X-ray c) CT scan d) Bone scan Answer: d) Bone scan What can be a result of excessive alcohol consumption on bone health? a) Increased bone density b) Decreased bone formation c) Enhanced calcium absorption d) Improved overall health Answer: b) Decreased bone formation What is the effect of glucocorticoids on bone health? a) Increase bone formation b) Inhibit bone resorption c) Cause bone loss d) Improve calcium absorption Answer: c) Cause bone loss Which lifestyle factor is crucial for maintaining bone health? a) Sedentary lifestyle b) Adequate physical activity c) High-sugar diet d) Low-protein intake Answer: b) Adequate physical activity What condition results from a lack of adequate vitamin D during childhood? a) Osteoporosis b) Rickets c) Osteogenesis imperfecta d) Osteoarthritis Answer: b) Rickets What is the primary function of osteoclasts in bone metabolism? a) Bone formation b) Bone resorption c) Bone repair d) Bone remodeling Answer: b) Bone resorption Which of the following can indicate an underlying metabolic bone disorder? a) Joint pain b) Fractures with minimal trauma c) Muscle cramps d) Skin rashes Answer: b) Fractures with minimal trauma  
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