Vitamins and Hormones MCQs

Set of Important MCQs on HORMONES AND VITAMINS for the preparation of tests for chemistry and biology. 

Which is correct regarding Cholecalciferol (Vit.D3)?

  1. It is a sterol
  2. It is converted to a biologically active form by UV light
  3. It is a hormone precursor
  4. Both A, B and C

Question Answer: It is a hormone precursor

All hormone receptor-enzymes:

  1. Alter gene expression
  2. Consist of more than one subunit
  3. Act by phosphorylating tyrosines
  4. Both A, B and C

Question Answer: Consist of more than one subunit

Which is correct regarding Steroid hormones?

  1. Bind cell surface receptors
  2. Meiate their effects through second messengers
  3. Have a very rapid effect (within seconds) on target cells
  4. Are insoluble in blood

Question Answer: Are insoluble in blood

Which enzymes requires biotin as a coenzyme?

  1. Pyruvate kinase
  2. Acetyl CoA carboxylase
  3. Phosphoenolpyruvate carboxykinase
  4. Both A, B and C

Question Answer: Acetyl CoA carboxylase

Group I hormones act through which of the following?

  1. Receptor enzymes
  2. G-protein coupled receptors
  3. Nuclear receptors
  4. Gated ion cannels

Question Answer: Nuclear receptors

Group II hormones do not act through which of the following?

  1. Receptor enzymes
  2. Nuclear receptors
  3. G-protein coupled receptors
  4. Gate ion channels

Question Answer: Nuclear receptors

Which chemical is not a 1hormone?

  1. Cyclic AMP (CAMP)
  2. Nitric oxide
  3. Retinoic acid
  4. Vitamin D

Question Answer: Cyclic AMP (CAMP)

Which happened in a cell as a result of insulin binding to its- receptor?

  1. Cyclic GMP is produced
  2. Glucose is released from the cell
  3. GLUT4 moves from the plasma membrane to internal membrane vesicles
  4. Glycogen synthase becomes activated

Question Answer: Glycogen synthase becomes activated

Which is correct regarding the hormone epinephrine?

  1. Its intracellular signal persists long after it has stopped binding its receptor
  2. It promotes the mobilization of glucose from glycogen
  3. It must be present in high concentrations to carry out its effects
  4. Both A, B and C

Question Answer: It promotes the mobilization of glucose from glycogen

Which is correct regarding Vitamin C?

  1. Helps in conversion of Beta carotenes to Vitamin A
  2. It helps in production of prothrombin
  3. It is essential for formation of collagen
  4. It helps in phosphorylation process

Question Answer: It is essential for formation of collagen

Of the two types of diabetes, Which situations is unique to type Il diabetes?

  1. An inability to take up glucose efficiently from the blood
  2. An inability to respond to insulin
  3. An inability to produce sufficient insulin
  4. High levels of glucose in urine

Question Answer: An inability to respond to insulin

Insulin causes all of the following excluding which of the following?

  1. Increased glucose uptake and utilization
  2. Increased amino acid uptake
  3. Increased fat utilization
  4. Shift of K from ECF to cells

Question Answer: Increased fat utilization

Synthesis of Na-K ATPase pump is stimulated by:

  1. ACTH
  2. Thyroid Hormones
  3. Epinephrine
  4. PTH

Question Answer: Thyroid Hormones

The release of insulin from the pancreas is triggered or stimulated by:

  1. Low intracellular levels of glucose
  2. A drop in intracellular ATP.
  3. The opening of Ca2+ channels in the plasma membrane
  4. Stimuli from the sympathetic nervous system.

Question Answer: The opening of Ca2+ channels in the plasma membrane

Insulin deficiency:

  1. Depresses protein synthesis
  2. Increases protein degradation
  3. Depresses Lipogenesis
  4. Increases nitrogen excretion

Question Answer: Depresses Lipogenesis

Insulin acts by all of the following, excluding which of the following?

  1. Stimulates glycogenesis
  2. Decreases renal reabsorption of Glucose
  3. Inhibits gluconeogenesis
  4. Increases utilization of glucose

Question Answer: Decreases renal reabsorption of Glucose

Thiouracil inhibits thyroid function by which of the following?

  1. Inhibition of pituitary
  2. Degradation of thyrotropin
  3. Formation of thiocyanate
  4. Inhibition of thyroxine synthesis.

Question Answer: Inhibition of thyroxine synthesis

Which of the following is the main and key mechanism of excretion of steroid hormones?

  1. Phenolic sulphate esters
  2. Estradiol
  3. Glucuronides
  4. Unchanged

Question Answer: Glucuronides

Which is the quickest acting hormone?

  1. Thyroid hormones
  2. Epinephrine
  3. Testosterone
  4. Vitamin D

Question Answer: Epinephrine

What are ‘Orphan Receptors’?

  1. The membrane receptors with unknown second messenger
  2. The membrane receptors with unknown ligand
  3. Nuclear hormone responsive element with unknown ligand
  4. Nuclear hormone responsive elements with unknown gene

Question Answer: Nuclear hormone responsive element with unknown ligand

Which is correct regarding leptin?

  1. It is synthesized in the hypothalamus
  2. It makes ATP synthesis more efficient
  3. It allows continuous oxidation of fatty acids
  4. Its levels in the blood are controlled by signals in the brain

Question Answer: It allows continuous oxidation of fatty acids

Which vitamin is responsible for vision?

  1. Vitamin D
  2. Retinol
  3. Tocopherols
  4. Vitamin K

Question Answer: Retinol

Which vitamin derivatives is the co-enzyme for amino-transferees?

A Pyridoxal phosphate

  1. Methyl Cobalamine
  2. NADH
  3. Tetrahydrofolate

Question Answer: Pyridoxal phosphate

Endogenous Vitamin D synthesis happened in?

  1. Skin
  2. Liver
  3. Epididymis
  4. Adrenal gland

Question Answer: Skin

Vitamin C is a cofactor in the enzymatic transformation of which of the following?

  1. Hydroxylysine to al-lysine (Aldehyde derivative)
  2. Glutamate to keto-glutarate
  3. Proline to hydroxyproline
  4. Lysine to desmosine

Question Answer: Proline to hydroxyproline

Which vitamins is important for Carboxylation reactions?

  1. Biotin
  2. Pyridoxine
  3. Ascorbic acid
  4. Tocopherol

Question Answer: Biotin

Vitamin which prevents auto-oxidation of fats and other molecules:

  1. Biotin
  2. Tocopherol
  3. Pyridoxine
  4. Vitamin A

Question Answer: Tocopherol

Vitamin essential for transamination reactions is:

  1. B6
  2. B2
  3. B1
  4. B12

Question Answer: B6

Vitamin B1 participates in which of the following?

  1. Single ‘N’ transfer
  2. Carboxylation
  3. Two-carbon transfer
  4. One-carbon transfer

Question Answer: Two-carbon transfer

Sulfa drugs such as sulfanilamide are effective antibacterial agents because they act as

  1. Competitive inhibitors for PABA Synthesis
  2. Noncompetitive inhibitors for PABA Synthesis
  3. Competitive Inhibitors of THF synthesis
  4. Competitive inhibitors for Folate synthesis

Question Answer: Competitive inhibitors for Folate synthesis

Water soluble Vitamin necessary for the synthesis of Coenzyme

  1. Vitamin C
  2. A Pantothenic acid
  3. Thiamine
  4. Biotin

Question Answer: A Pantothenic acid

Which one of the following vitamins is a precursor of the coenzyme involved in well glycogenolysis decarboxylation reactions?

  1. thiamine
  2. Pantothenic acid
  3. Pyridoxine
  4. Folate

Question Answer: Pyridoxine

Vitamin Biz is a:

  1. Porphyrin-like compound
  2. Copper containing vitamin
  3. Fat Soluble vitamin
  4. Growth factor essential for E coli

Question Answer: Porphyrin-like compound

Which of the following is the most active form of Vitamin-D?

  1. 1 a calciferol
  2. 24. 25 dihydroxycalciferol
  3. 25 Hydroxycholecalciferol
  4. 1. 25 dihydroxycholecalciferol

Question Answer: 1. 25 dihydroxycholecalciferol

Methylmalonicaciduria is seen in deficiency of which of the following?

  1. Pyridoxine
  2. Riboflavin
  3. Cobalamine
  4. Folic Acid

Question Answer: Cobalamine

Glucagon initiated phosphorylation.

  1. Activates glycogen phosphorylase
  2. Activates lipoprotein lipase
  3. Deactivates adipose tissue lipase
  4. Both A, B and C

Question Answer: Activates glycogen phosphorylase

Which vitamins acts like a hormone?

  1. Vitamin D
  2. Vitamin A
  3. Vitamin E
  4. Both ‘A’ and ‘B’

Question Answer: Both ‘A’ and ‘B’

Which is not seen in scurvy

  1. Impaired cement formation
  2. Impaired trabeculation
  3. Osteoporosis
  4. Impaired cartilage

Question Answer: Osteoporosis

Vitamin B12 participates in the metabolism of:

  1. Odd chain fatty acids
  2. Malonyl CoA to Succinyl CoA
  3. Homocysteine to Methionine
  4. Both A, B and C

Question Answer: Both A, B and C

Patients with severe renal disease may not be able to use dietary sources for

  1. Vitamin A
  2. Vitamin B
  3. Vitamin D
  4. Vitamin C

Question Answer: Vitamin D

Growth of bacteria requiring p- aminobenzoic acid is inhibited by:

  1. Sulphonamides
  2. Citrovounm factor
  3. Tetrahydrofolic acid
  4. Penicillin

Question Answer: Sulphonamides

Vitamin A hypervitaminosis causes injury to:

  1. Mitochondria
  2. Lysosomes
  3. Microtubules
  4. Endoplasic reticulum

Question Answer: Lysosomes

Which is formed without participation of any vitamin?

  1. Gamma-carboxy-Glutamate
  2. Hydroxyproline
  3. Hydroxylysine
  4. Phosphoserine

Question Answer: Phosphoserine

Biological activity of tocopherols has been attributed, in part, to their action

  1. Anticoagulants
  2. Antioxidant
  3. Antidotes for selenium poisoning
  4. Both A, B and C

Question Answer: Antioxidant

Serpentine receptors (G-Protein coupled receptors)

  1. Generate second messengers
  2. Are ion channels
  3. Act in the nucleus
  4. Have a single trans membrane domain

Question Answer: Generate second messengers

Which is correct regarding steroid hormones?

  1. They are all derived from testosterone
  2. They travel through blood stream on protein carriers
  3. They are all synthesized in adrenal gland
  4. They carry messages between tissues

Question Answer: They travel through blood stream on protein carriers

Dermatitis, diarrhea and dementia are seen in deficiency of:

  1. Thiamine
  2. Riboflavin C. N
  3. Folate
  4. Niacin

Question Answer: Niacin

Cholesterol is a precursor molecule for all of the following, excluding which of the following?

  1. Testosterone
  2. Vitamin D
  3. Vitamin K
  4. Bile salts

Question Answer: Vitamin K

Which is a cofactor for fatty acid biosynthesis?

  1. Thiamine
  2. Pyridoxal Phosphate
  3. Cobalamine
  4. Biotin

Question Answer: Biotin

Which vitamins is needed for the optimum activity of tryptophan pyrrolase?

  1. Thiamine
  2. Vitamin Biz
  3. Folic acid
  4. Vitamin C

Question Answer: Thiamine

Which vitamins is needed in the conversion of pyruvate to oxaloacetate?

  1. B1
  2. Pyridoxine
  3. Vitamin C
  4. Biotin

Question Answer: Biotin

Now-a-days it is thought that this vitamin is very important to withstand stressful conditions:

  1. Vitamin A
  2. Vitamin C
  3. Vitamin B12
  4. Vitamin D

Question Answer: Vitamin C

Every hormone __________.

  1. Are able to enter their target cells
  2. Are water-soluble
  3. Act through binding receptors.
  4. Act by changing the expression of specific genes

Question Answer: Act through binding receptors

The high ‘Sensitivity’ of signal transduction is because of which of the following?

  1. High concentration of the hormone
  2. Amplification of the signal through a multistep activation
  3. Specificity of hormone-receptor interaction
  4. Both A, B and C

Question Answer: Amplification of the signal through a multistep activation

Vitamin needed carbohydrate intake: in increased

  1. B12
  2. B6
  3. B1
  4. Pantothenic acid

Question Answer: B1

Which water-soluble vitamins is not important for the normal activity of the Krebs cycle?

  1. Riboflaving
  2. Pantothenic acid
  3. Biotin
  4. Thiamine

Question Answer: Biotin

Which is correct regarding endocrine function?

  1. The endocrine molecule acts on the cell of its synthesis
  2. The endocrine molecules acts on the cell adjacent to that of its synthesis
  3. All endocrine molecules require a receptor to act
  4. All endocrine molecules stimulate synthesis of specific proteins

Question Answer: All endocrine molecules require a receptor to act

Chemically, the hormones are _______.

  1. Polypeptides
  2. Neurotransmitters
  3. Steroids
  4. Both A, B and C

Question Answer: Both A, B and C

Biotin:

  1. Serves as a cofactor in dehydrogenase reactions
  2. Transfers one-carbon groups
  3. Is a co-factor that transfers acetyl groups
  4. Both A, B and C

Question Answer: Transfers one-carbon groups

Methotrexate is helpful and used as an anticancer drug because it ________.

  1. Competitively inhibits the conversion of dihydrofolate to tetrahydrofolate
  2. Irreversibly inhibits the conversion of dihydrofolate to tetrahydrofolate
  3. Directly inhibits DNA synthesis
  4. Competitively inhibits the synthesis of folate

Question Answer: Competitively inhibits the conversion of dihydrofolate to tetrahydrofolate

Thiamine deficiency can be diagnosed by which of the following?

  1. Blood Pyruvate estimation
  2. Urinary thiamine levels
  3. RBC Transketolase estimation
  4. Both A, B and C

Question Answer: Both A, B and C

The highest concentration of Ascorbic acid is found in:

  1. Adrenal gland
  2. Kidneys
  3. Testes
  4. Eye

Question Answer: Adrenal gland

Normal urinary excretion of ascorbic acid is:

  1. 5-10 mg/24 h
  2. 10-15 mg/24 h
  3. 50-100 mg/24 h
  4. 15-50 mg/24 h

Question Answer: 15-50 mg/24 h

Following vitamin is usually excreted both through feces as well as urine:

  1. Pyridoxine
  2. Folic acid
  3. Pantothenic acid
  4. Vitamin B12

Question Answer: Folic acid

In scurvy, the main biochemical defect lies on:

  1. Formation of hydroxyproline
  2. Attachment of sugars to Asn
  3. Non-covalant linkage between strands
  4. Cross-liking of Tropocollagen

Question Answer: Formation of hydroxyproline

A vitamin related to a co-factor glycine metabolism is:

  1. Folic acid
  2. Vitamin E
  3. Thaimine
  4. Cobamidě

Question Answer: Folic acid

Vitamin K plays important role in ______.

  1. Posttranslational modification of proteins
  2. Synthesis of Osteocalcin
  3. Synthesis of prothrombin proconvertin
  4. Both A, B and C

Question Answer: Both A, B and C

Part of the Nicotinic acid requirement of the body may be fulfilled from:

  1. Pyridoxine
  2. Tyrosine
  3. Tryptophan
  4. Methionine

Question Answer: Tryptophan

Which is not a feature of niacin deficiency?

  1. Conjunctival congestion

B: Red tongue

  1. Psychosis
  2. Diarrhea

Question Answer: Conjunctival congestion

More Biochemistry MCQs

  1. Acid and Base MCQs
  2. Carbohydrate MCQs
  3. Proteins MCQs
  4. Lipids and Biomembranes MCQs
  5. Nucleic acids MCQs
  6. Metabolism of Carbohydrates MCQs
  7. Enzymes MCQs
  8. Vitamins and Hormones MCQs
  9. Bioenergetic MCQs
  10. Biotechnology MCQs
  11. Biotechnology MCQs 2
  12. Basic Biochemistry MCQs (important)
  13. CHEMISTRY MCQs From all subjects of  Chemistry
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