- NH3
- Pyridine
- H2O
- BF
The difference in the pH of arterial and venous blood is very minor because of the interaction between:
- Hemoglobin and bicarbonate buffers
- Hemoglobin and plasma proteins
- Bicarbonate and phosphate buffers
- Phosphate buffer and plasma proteins
Which concept is also called as proton-donor acceptor system?
- Usanovich
- Lewis
- Lux-Flood
- Bronsted-Lowery
Which concept is also called as electron pair-donor acceptor system?
- Bronsted-Lowery
- Lewis
- Lux-Flood
- Usanovich
The pKa of an acid is defined as
- The pH at which the acid starts dissociating
- Negative log of its ionization constant
- The pH at which all the ionizable residues are half dissociated
- None of these
According to ______ “Acids are substances whose aqueous solutions turned blue litmus red and tasted sour”.
- Boyle
- Liebig
- Davy
- Rouelle
An acid is a substance that results in __.
- Accepts electrons from a donor
- Gives a hydronium ion
- Yields an hydride ion
- All of these
Which is not a fixed acid?
- Citric acid
- Carbonic acid
- Phosphoric acid
- Lactic acid
Which acid-base conditions is characterized by primary carbonic acid excess?
- Respiratory alkalosis
- Metabolic
- Metabolic alkalosis acidosis
- Respiratory acidosis
According to which effect, All the strong acids have very close pKa value and they seem to have approximately equal strengths in aqueous solutions?
- Leveling effect
- Electrophoretic effect
- Debye effect
- Solvent effect
Relative order of acidity of HF, HCl, HBr and HI acids is:
- HI> HBr > HCl > HF
- HF> HCI > HBr >
- HCl > HBr > HI> HF
- HF> HI>HCI > Br
Relative order of acidity of oxy acids is:
- HCIO> HCIO2> HCIO3> HCIO4
- HCIO4> HCIO3> HCIO2> HCIO
- HCIO3>HCIO₂> HCIO> HCIO4
- HCIO2>HCIO4> HCIO3> HCIO
pH of pure water at 25°C and Kw = 1 x 10
- 7
- 0
- 14
- None of these
The ionic product equilibrium constant of water is
- Ka
- Kb
- Kw
- Kc
Which is not true with respect to buffers?
- They are made up of strong acid and weak base
- They are made up of weak base and its salt
- They tend to resist a change in pH value
- They are made up of weak acid and its salt
The value of Kw increases with temperature ______.
- Decreases because the ionization of water
- Increases
- Remains constant
- First decreases and then increases
The bicarbonate buffer system of our body has pK _______.
- 7.6
- 6.5
- 7.2
- 6.1
What is the pH of the tears?
- 8.2
- 3.2
- 7.4
- 8.2
What is the pH of milk?
- 6.5
- 6.0
- 7.0
- 7.5
What is the pH of the 0.1 M HCl solution?
- 0.01
- 2.1
- 1
- 0.2
What is the pH of the 1 M HCl?
- 1
- 2.1
- 0
- 1.3
The sum of pH and pOH is equal to which of the following?
- 1
- 14
- 13
- 2
Buffer solution are helpful and used to
- Resist the pH change
- Decrease the pH
- Increase the pH
- None of these
A mixture of weak acid and its salt is
- Acidic buffer
- Alkaline buffer
- Neutral buffer
- None of these
Glass electrode cannot be helpful and used to measure the pH of pure
- Acetic acid
- Gelatin
- Ethyl alcohol
- All of these
The pH value 4.2 is of:
- Vinegar
- Tomatoes
- Oranges
- Lemons
If the pH of solution is 1, its pOH will be
- 11
- 13
- 9
- 10
Which is not Lowery-Bronsted acid?
- HCI
- Cl
- HS-
- H2O
Which is not Lowery-Bronsted Base?
- NH3
- H2O
- HCI
- HS
Which is not Lewis acid?
- Cl
- BF3
- AlCl3
- HCI
Which is not true with respect to strong acids?
- They have a pK value of less than 3
- Higher K value means strong acid
- They can have more than one pK
- Lowering the pH below their pK will cause their dissociation
Which amino acids is responsible for buffer action in blood?
- Pyridine
- Glutamine
- Histidine
- Glycine
Which amino acids has S-S bond?
- Cistine
- Cisteine
- Glutamine
- Histidine
Which buffers is not present in the blood?
- Carbonate-bicarbonate buffer
- Phosphate buffer
- Tris/ HCl buffer
- Protein buffer
Which is not true with respect to carbonate buffers?
- It is an open system
- The bicarbonate concentration is mainly qontrolled by lungs
- The dissolved CO2 is in equilibrium with the CO2 gas
- Bicarbonate is non-respiratory component of the buffer system
What is the approximate percentage of water in the body?
- 60%
- 50%
- 40%
- 70%
Which is the percentage of intracellular fluids in the body?
- 70%
- 50%
- 60%
- 40%
How much metabolic water is produced per 100 calories of energy produced in human body?
- 10-15 mL
- 1-5 mL
- 25-50 mL
- 50-100 mL
Which results in generation of highest amount of metabolic water (per gram oxidation of the substance)?
- Carbohydrates
- Proteins
- Fats
- Nucleic acids
Which has higher concentration in the extracellular compartment than the intracellular?
- Magnesium
- Phosphate
- Sulphate
- Bicarbonate
Which does not contribute to the osmolality?
- Urea
- Proteins
- Sodium
- Pyric acid
Which of the following happens due to Donnan effect?
- Concentartion of the anions is higher in the interstitial fluids
- Concentartion of the catios is higher in the interstitial fluids
- Proteins bind chloride at physiological pH
- Sodium and potassium laek out of plasma
Which is minimum?
- Metabolic water
- Water lost in sweat
- Water in food
- Daily urinary output
What is the pH of the blood?
- 4.3
- 8.2
- 6.1
- 7.4
Which is not true with respect to pKa value?
- The stronger the acid, the smaller its pKa value
- The stronger the acid, the larger its pKa value
- The stronger the base, the larger its pKa value
- The pKa value can be determined experimentally
Which aqueous solution has low pH value?
- 0.1 M acetic acid
- 0.1 M hydrochloric acid
- 0.1 M formic acid
- 0.1 M phosphoric acid
Which mixture does not act as buffers?
- Acetic acid/sodium acetate
- Phosphoric acid/sodium phospahte
- Trisbase/HCl
- Sodium chloride/hydrochloric acid
Which statement is not true about amino acid glycine?
- It is a main ingredient of buffers helpful and used in biochemical experiments
- The amino group of glycine has a pKa value 4.74
- The amino group can exist in protonated form
- The amino group can exist in free form
Which combinations is helpful and used to prepare buffers of pH 7.0?
- Acetic acid/sodium acetate
- Sodium borate/boric acid
- Phosphoric acid/sodium phosphate
- Tribase/HCl
The pH of human stomach is
- 6.0 to 7.0
- 4.0 to 6.0
- 1.5 to 2.5
- None of these
Which biochemical reactions involve water as reactant?
- Hydrolysis
- Condensation
- Redox
- All of these
What is the optimum range for best working of acetate buffer?
- 1.76-4.76
- 2.76-3.76
- 3.76-5.76
In water at 25°C, the concentration of water is ______.
- 54.5 M
- 55.5 M
- 53.5 M
- 52.5 M
Which properties of water is not associated with H-bonding?
- Higher M.P.
- Higher B.P.
- High density
- Heat of vaporization
Which bond is weak?
- H-bond
- Ionic bond
- Covalent bond
- Metallic bond
Which is not true with respect to hemoglobin?
- hemoglobin can bind CO2 to form carboxyhemoglobin
- hemoglobin acts as buffer because carboxyhemoglobin is a strong acid
- The deoxyhemoglobin in tissues is bound to proton
- In RBC, the formation of carbonic acid is facilitated by carbonic anhydrase
Amphipathic compounds are substances that contain regions
- Non-polar regions
- Polar regions
- Both polar and non-polar
- None of these
The forces that hold the non-polar regions of the molecules together are referred as
- H-bonding
- Hydrophobic interactions
- Dipole interactions
- van der Waals forces
Which biomolecules are amphipathic?
- Proteins
- Phospholipids
- Pigments
- All of these
Solutes of all kinds alter certain physical properties of water (vapor pressure, B.P. osmotic pressure). These are called
- Colligative properties
- Additive properties
- Chemical properties
- Constitutive properties
The pH at which the dipolar ion does not migrate in an electric field is called
- Isobestic point
- Critical point
- Neutral point
- Isoelectric point
The isoelectric point of glycine amino acid is
- 3.98
- 1.98
- 2.98
- 4.98
Solutions of osmolarity equal to that of cells cytosol are said to be
- Hypertoinc
- Hypotonic
- Isotonic
- None of these
Solutions of osmolarity higher to that of cell,s cytosol are said to be
- Hypotonic
- Isotonic
- Hypertoinc
- None of these
Solutions of osmolarity lower to that of cells cytosol are said to be
- Hypotonic
- Isotonic
- Hypertoinc
- None of these
Which acids is polyprotic acid?
- Sulfuric acid
- Phosphoric acid
- Carbonic acid
- All of these
Which amino acids is not optically active?
- Histidine
- Alanine
- Glycine
- Glutamine
Which amino acids has L- configuration?
- Glutamine
- Alanine
- Histidine
- All of these
Which amino acids contains imidazole ring?
- Pyridine
- Glycine
- Glutamine
- Histidine
Which is a biological buffer(s)?
- MES monohydrate.
- MOPS
- HEPES
- All of these
Which amino acids have two carboxylic groups?
- Glutamine
- Histidine
- Aspartic acid
- Glycine
Which amino acids have two amino groups?
- Aspartic acid
- Isoleucine
- Glycine
- Asparagine
When two charged atoms are brought together, their surrounding electron clouds influence each other and create transient electric dipoles which attract each other. These weak attractions are called –
- H-bonding
- van der Waals interactions
- Dipole interactions
- Hydrophobic interactions
Lewis concept explain the formation of
- Co-ordinate bond
- Covalent bond
- Ionic bond
- Hydrogen bond
The pK of an acid ______.
- Is an indicator of the strength of the buffer
- Signifies the buffering capacity of the buffer solution
- Reflects the pH of a solution
- Diffusion
- Osmosis
- Donann equilibrium
- None of these
More Biochemistry MCQs
- Acid and Base MCQs
- Carbohydrate MCQs
- Proteins MCQs
- Lipids and Biomembranes MCQs
- Nucleic acids MCQs
- Metabolism of Carbohydrates MCQs
- Enzymes MCQs
- Vitamins and Hormones MCQs
- Bioenergetic MCQs
- Biotechnology MCQs
- Biotechnology MCQs 2
- Basic Biochemistry MCQs (important)
- CHEMISTRY MCQs From all subjects of Chemistry