Nucleic acids MCQs

By: Prof. Dr. Fazal Rehman | Last updated: May 22, 2025

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1. : Which one of the following vitamins plays an important role in the biosynthesis of purine nucleotides?



2. : Which is correct about bacterial chromosome?



3. : “PCR” technique is useful for:



4. : What is the number of hydrogen bonds existing in G-C pair?



5. : Which of the following is the base which is not existing in DNA?



6. : Which is not a pyrimidine base?



7. : The sugar existing in DNA is:



8. : Which among the following is the sugar existing in RNA?



9. : Which is the unit of nucleic acid having base-sugar combination?



10. : Cytosine, a pyrimidine base, pairs with which of the following?



11. : What is the number of hydrogen bonds holding A-T pair?



12. : Adenosine nucleoside has the base:



13. : RNA is involved in the synthesis of which of the following?



14. : Which of the following is the formation of daughter DNA’s from parent DNA?



15. : Which of the following is the procedure of transfer of genetic message from DNA to m-RNA?



16. : Hydrogen bonds holding the strands of nucleic acids are formed between ______ and _____.



17. : Codon for amino acid glycine is not represented by base pair:



18. : Anticodons in t-RNA’s corresponding to different amino acids ________.



19. : One arm of each t-RNA terminates in the base sequence:



20. : The binding site on ribosome for t-RNA and m-RNA is offered by which of the following?



21. : Biological role of nucleic acid does not include which of the following?



22. : The steps involved in biosynthesis of protein includes which of the following?



23. : How many nucleoprotein subunits does the mammalian ribosome contain?



24. : Which is the most abundant intracellular free nucleotide?



25. : Hypoxanthine and ribose are components of _______ molecules.



26. : Which are adapter molecules that translate genetic code into amino acid sequence?



27. : All tRNA molecules have a common CCA sequence at the ______ termini.



28. : A prokaryotic polypeptide of 300 amino acids is encoded by how many base pairs of DNA?



29. : AUG, the only identified codon for methionine, is important as ______.



30. : The anticodon region is an important part of the structure of which of the following?



31. : The chief end product of purine catabolism in man is _____.



32. : DNA can be denatured by which of the following?



33. : The chemical name 2-amino-6-oxypurine is for ____.



34. : The four nitrogen atoms in purine ring are derived from which of the following?



35. : Each turn of DNA structure has a pitch in ____nm.



36. : Which statement is correct about histones?



37. : The chemical name of thymine would be:



38. : The N atoms at position 3 and 9 of purine base are derived from the amide nitrogen____



39. : Posttranscriptional modification of tRNA involves adding of which of the following?



40. : The end product of purine catabolism is ________ in other mammals, excluding man.



41. : The transfer-RNA approximately molecule comprises how many nucleotides?



43. : The structural stability of the double helix of DNA is largely the result of which of the following?



44. : A mature mRNA could be lengthier than its precursor pre-mRNA due to which of the following?



45. : Which processes does not happen in the nucleus of eukaryotes?



46. : How many energy bonds are helpful and used up during the elongation step in protein synthesis?



47. : mRNA is a complimentary copy of which?



48. : For DNA-dependent RNA synthesis



49. : Which statements regarding a double-helical of DNA is correct?



50. : Which is NOT correct regarding eukaryotic mRNA?



51. : Translocate is an enzyme required in the process of:



52. : Nonsense codons bring about ________.



53. : Which is not a component of polysomes?



54. : In which way are the genomes of prokaryotes and eukaryotes similar?



55. : Which is NOT CORRECT about genetic code?



56. : Reverse transcriptase enzyme catalyzes



57. : Where does protein synthesis take place predominantly in mammalian secretory cells?



58. : DNA ligase:



59. : When double-stranded DNA is slowly warmed at 85°C?



60. : The term “Transforming factors” has been helpful and used for _______ ?



61. : An accurate DNA replication needs all of the following, EXCLUDING



62. : The purine nucleotides act as components of: factor



63. : Approximately how many mg of uric acid is synthesized in a normal man in 24 hours?



64. : Which is correct about DNA gyrase?



65. : Promoters:



66. : Which is correct about reverse transcriptase?



67. : The normal function of restriction endonucleases is to:



68. : The E.coli RNA polymerase binding to the promoter site is inhibited by:



69. : Which is NOT a purine base?



70. : Hydrolysis of nucleoprotein results in the formation of which of the following?



71. : Complete hydrolysis of nucleotides results in the formation of which of the following?



72. : Which proteins unwind the two parental DNA strands in E.coli?



73. : PCR can be helpful and used for:



74. : Foot-printing technique is helpful and used to:



75. : Which nucleotide is helpful and used for epimerization of galactose to glucose?



76. : Which compound is structural analogue of hypoxanthine and competitively inhibits xanthine oxidase?



77. : Which is correct for ‘Alternative splicing’?



78. : Which is not existing in both E.coli and human mRNA?



 

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