Bone Tumors MCQs

By: Prof. Dr. Fazal Rehman Shamil | Last updated: September 28, 2024

What is the most common primary bone tumor in adults?
A) Osteosarcoma
B) Chondrosarcoma
C) Multiple myeloma
D) Ewing sarcoma
Answer: C) Multiple myeloma

Which of the following is a benign bone tumor?
A) Osteosarcoma
B) Osteoid osteoma
C) Chondrosarcoma
D) Ewing sarcoma
Answer: B) Osteoid osteoma

What is the hallmark radiological feature of osteosarcoma?
A) Onion-skin appearance
B) Codman’s triangle
C) Ground-glass appearance
D) Sunburst pattern
Answer: D) Sunburst pattern

Which bone tumor is most commonly found in the metaphysis of long bones?
A) Osteosarcoma
B) Ewing sarcoma
C) Chondrosarcoma
D) Giant cell tumor
Answer: A) Osteosarcoma

Which age group is most commonly affected by Ewing sarcoma?
A) Children and adolescents
B) Middle-aged adults
C) Elderly
D) Infants
Answer: A) Children and adolescents

What is the primary site for metastasis of osteosarcoma?
A) Brain
B) Liver
C) Lungs
D) Kidneys
Answer: C) Lungs

What is a common symptom of bone tumors?
A) Weight gain
B) Bone pain
C) Frequent infections
D) Skin rashes
Answer: B) Bone pain

Which tumor has a characteristic “onion-skin” periosteal reaction on X-ray?
A) Osteosarcoma
B) Chondrosarcoma
C) Ewing sarcoma
D) Giant cell tumor
Answer: C) Ewing sarcoma

Which of the following is a primary malignant bone tumor?
A) Osteochondroma
B) Chondroma
C) Osteosarcoma
D) Osteoid osteoma
Answer: C) Osteosarcoma

Which tumor is typically located in the epiphysis of long bones?
A) Osteosarcoma
B) Giant cell tumor
C) Chondrosarcoma
D) Ewing sarcoma
Answer: B) Giant cell tumor

Which of the following bone tumors is associated with a genetic mutation?
A) Osteoid osteoma
B) Osteosarcoma
C) Chondrosarcoma
D) Osteochondroma
Answer: B) Osteosarcoma

Which bone tumor is known for producing cartilage matrix?
A) Osteosarcoma
B) Chondrosarcoma
C) Ewing sarcoma
D) Giant cell tumor
Answer: B) Chondrosarcoma

What is the preferred treatment for benign bone tumors?
A) Chemotherapy
B) Radiation therapy
C) Surgical excision
D) Immunotherapy
Answer: C) Surgical excision

Which imaging technique is most useful in evaluating bone tumors?
A) Ultrasound
B) X-ray
C) MRI
D) PET scan
Answer: C) MRI

Which tumor is more likely to occur in the pelvis and shoulder?
A) Osteosarcoma
B) Chondrosarcoma
C) Ewing sarcoma
D) Giant cell tumor
Answer: B) Chondrosarcoma

What is the most common symptom of a giant cell tumor?
A) Joint instability
B) Localized pain and swelling
C) Fatigue
D) Fever
Answer: B) Localized pain and swelling

What is the first-line treatment for osteosarcoma?
A) Radiation
B) Chemotherapy and surgery
C) Hormonal therapy
D) Antibiotics
Answer: B) Chemotherapy and surgery

Which benign bone tumor is commonly associated with night pain relieved by NSAIDs?
A) Osteoid osteoma
B) Chondroblastoma
C) Fibrous dysplasia
D) Aneurysmal bone cyst
Answer: A) Osteoid osteoma

Which tumor is characterized by aggressive local growth and potential metastasis to the lungs?
A) Osteoid osteoma
B) Giant cell tumor
C) Ewing sarcoma
D) Chondrosarcoma
Answer: B) Giant cell tumor

What is the typical age group affected by osteochondroma?
A) Infants
B) Adolescents and young adults
C) Middle-aged adults
D) Elderly
Answer: B) Adolescents and young adults

Which of the following is a rare benign tumor that occurs in the skull or spine?
A) Osteoblastoma
B) Ewing sarcoma
C) Chondrosarcoma
D) Osteoid osteoma
Answer: A) Osteoblastoma

What is the gold standard for diagnosing bone tumors?
A) X-ray
B) MRI
C) Bone biopsy
D) CT scan
Answer: C) Bone biopsy

Which tumor is known to produce a “soap bubble” appearance on X-ray?
A) Giant cell tumor
B) Osteosarcoma
C) Chondrosarcoma
D) Osteoid osteoma
Answer: A) Giant cell tumor

Which tumor is commonly associated with pathologic fractures?
A) Osteosarcoma
B) Chondroma
C) Ewing sarcoma
D) Giant cell tumor
Answer: D) Giant cell tumor

Which type of bone tumor commonly metastasizes to the lungs and is highly aggressive?
A) Osteoid osteoma
B) Osteosarcoma
C) Enchondroma
D) Osteochondroma
Answer: B) Osteosarcoma

Which tumor is primarily treated with curettage and bone grafting?
A) Chondrosarcoma
B) Osteosarcoma
C) Giant cell tumor
D) Ewing sarcoma
Answer: C) Giant cell tumor

Which of the following is a primary bone cancer that typically affects younger patients?
A) Multiple myeloma
B) Osteosarcoma
C) Chondrosarcoma
D) Metastatic carcinoma
Answer: B) Osteosarcoma

What type of tumor is often described as “moth-eaten” on radiographs?
A) Ewing sarcoma
B) Osteosarcoma
C) Chondrosarcoma
D) Osteochondroma
Answer: A) Ewing sarcoma

Which genetic condition is associated with multiple osteochondromas?
A) Neurofibromatosis
B) Ollier disease
C) Hereditary multiple exostoses
D) Marfan syndrome
Answer: C) Hereditary multiple exostoses

What is the typical age of onset for osteosarcoma?
A) 10-20 years
B) 30-40 years
C) 50-60 years
D) 70-80 years
Answer: A) 10-20 years

Which type of bone tumor is least likely to be malignant?
A) Osteosarcoma
B) Chondrosarcoma
C) Osteochondroma
D) Ewing sarcoma
Answer: C) Osteochondroma

Which tumor is characterized by a central nidus surrounded by sclerosis?
A) Osteoid osteoma
B) Ewing sarcoma
C) Osteosarcoma
D) Chondrosarcoma
Answer: A) Osteoid osteoma

Which type of bone tumor is associated with a poor prognosis due to its aggressive nature and high rate of metastasis?
A) Osteosarcoma
B) Osteochondroma
C) Osteoid osteoma
D) Enchondroma
Answer: A) Osteosarcoma

Which tumor is more likely to be found in the diaphysis of long bones?
A) Ewing sarcoma
B) Osteosarcoma
C) Giant cell tumor
D) Chondrosarcoma
Answer: A) Ewing sarcoma

What is the most common treatment for chondrosarcoma?
A) Chemotherapy
B) Radiation therapy
C) Surgical resection
D) Immunotherapy
Answer: C) Surgical resection

Which imaging modality is most sensitive for detecting bone marrow involvement in tumors?
A) X-ray
B) MRI
C) CT scan
D) Ultrasound
Answer: B) MRI

Which bone tumor is often associated with pain at night and relief with aspirin?
A) Osteoid osteoma
B) Osteosarcoma
C) Chondrosarcoma
D) Ewing sarcoma
Answer: A) Osteoid osteoma

What is the treatment approach for benign osteochondromas?
A) Chemotherapy
B) Radiation therapy
C) Observation or surgical removal if symptomatic
D) Bone marrow transplant
Answer: C) Observation or surgical removal if symptomatic

Which of the following bone tumors can arise from cartilage?
A) Osteosarcoma
B) Ewing sarcoma
C) Chondrosarcoma
D) Giant cell tumor
Answer: C) Chondrosarcoma

What is the typical radiographic appearance of osteochondroma?
A) Pedunculated or sessile lesion
B) Lytic lesion with sclerotic borders
C) Onion-skin periosteal reaction
D) Ground-glass appearance
Answer: A) Pedunculated or sessile lesion

Which bone tumor is more common in the vertebrae?
A) Osteosarcoma
B) Osteoblastoma
C) Chondrosarcoma
D) Giant cell tumor
Answer: B) Osteoblastoma

Which tumor is more commonly found in the pelvis, ribs, and femur?
A) Osteosarcoma
B) Chondrosarcoma
C) Ewing sarcoma
D) Osteoid osteoma
Answer: B) Chondrosarcoma

What is a common complication of untreated bone tumors?
A) Skin rash
B) Pathological fractures
C) Hypercalcemia
D) Osteoporosis
Answer: B) Pathological fractures

Which bone tumor often presents with localized swelling and tenderness?
A) Osteoid osteoma
B) Ewing sarcoma
C) Osteochondroma
D) Chondrosarcoma
Answer: B) Ewing sarcoma

Which bone tumor is associated with the production of osteoid?
A) Osteosarcoma
B) Chondrosarcoma
C) Giant cell tumor
D) Ewing sarcoma
Answer: A) Osteosarcoma

What is the typical histological finding in Ewing sarcoma?
A) Spindle-shaped cells
B) Small, round blue cells
C) Cartilaginous matrix
D) Osteoid deposition
Answer: B) Small, round blue cells

Which bone tumor is characterized by a mix of fibrous and osseous tissue?
A) Fibrous dysplasia
B) Osteochondroma
C) Osteosarcoma
D) Giant cell tumor
Answer: A) Fibrous dysplasia

 

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