Benign vs malignant bone tumors MCQs

By: Prof. Dr. Fazal Rehman Shamil | Last updated: September 28, 2024

Which of the following is a characteristic of benign bone tumors?
A) Slow growth
B) Infiltrative growth
C) Frequent metastasis
D) Painful in early stages
Answer: A) Slow growth

What is the typical radiographic appearance of malignant bone tumors?
A) Well-defined borders
B) Sclerotic margins
C) Lytic and destructive patterns
D) Central calcifications
Answer: C) Lytic and destructive patterns

Which of the following is a benign bone tumor?
A) Osteosarcoma
B) Osteoid osteoma
C) Chondrosarcoma
D) Ewing sarcoma
Answer: B) Osteoid osteoma

What feature distinguishes malignant bone tumors from benign bone tumors?
A) Pain at night
B) Well-circumscribed margins
C) Potential for metastasis
D) Occurrence in adolescents
Answer: C) Potential for metastasis

Which of the following is most likely to metastasize to the lungs?
A) Osteochondroma
B) Osteosarcoma
C) Osteoid osteoma
D) Enchondroma
Answer: B) Osteosarcoma

What is the common age group affected by benign bone tumors?
A) Infants
B) Adolescents
C) Middle-aged adults
D) Elderly
Answer: B) Adolescents

Which benign bone tumor commonly affects the spine?
A) Osteosarcoma
B) Osteoblastoma
C) Ewing sarcoma
D) Chondrosarcoma
Answer: B) Osteoblastoma

Which malignant bone tumor is characterized by a “sunburst” pattern on X-ray?
A) Osteosarcoma
B) Chondrosarcoma
C) Ewing sarcoma
D) Giant cell tumor
Answer: A) Osteosarcoma

Which tumor is considered a benign cartilage-forming tumor?
A) Chondrosarcoma
B) Osteochondroma
C) Ewing sarcoma
D) Osteosarcoma
Answer: B) Osteochondroma

What is a distinguishing feature of giant cell tumors?
A) They are benign but locally aggressive
B) They metastasize frequently
C) They occur in the diaphysis of long bones
D) They are common in elderly patients
Answer: A) They are benign but locally aggressive

Which tumor type is typically well-circumscribed and non-invasive?
A) Malignant
B) Benign
C) Both
D) Neither
Answer: B) Benign

What is the primary treatment for benign bone tumors?
A) Chemotherapy
B) Radiation therapy
C) Surgical excision
D) Observation
Answer: C) Surgical excision

Which of the following is more likely to show periosteal reaction on imaging?
A) Benign bone tumors
B) Malignant bone tumors
C) Both
D) Neither
Answer: B) Malignant bone tumors

Which bone tumor is more common in children and adolescents?
A) Osteosarcoma
B) Chondrosarcoma
C) Multiple myeloma
D) Osteoid osteoma
Answer: A) Osteosarcoma

What is a typical characteristic of malignant bone tumors on MRI?
A) Homogeneous appearance
B) High signal intensity on T1
C) Soft tissue invasion
D) Presence of calcifications
Answer: C) Soft tissue invasion

Which benign tumor commonly arises from cartilage and is often asymptomatic?
A) Osteoid osteoma
B) Chondroblastoma
C) Enchondroma
D) Osteosarcoma
Answer: C) Enchondroma

Which tumor type is more likely to present with a pathologic fracture?
A) Benign
B) Malignant
C) Both
D) Neither
Answer: B) Malignant

Which of the following is a common symptom of both benign and malignant bone tumors?
A) Weight gain
B) Bone pain
C) Night sweats
D) Hair loss
Answer: B) Bone pain

What is a hallmark feature of benign bone tumors on X-ray?
A) Poorly defined margins
B) Expansile but without cortical breach
C) Soft tissue mass
D) Infiltrative appearance
Answer: B) Expansile but without cortical breach

Which tumor type is associated with Codman’s triangle on X-ray?
A) Benign tumors
B) Malignant tumors
C) Both
D) Neither
Answer: B) Malignant tumors

Which bone tumor is considered benign and frequently found in the epiphysis of long bones?
A) Osteosarcoma
B) Ewing sarcoma
C) Giant cell tumor
D) Chondrosarcoma
Answer: C) Giant cell tumor

What is the typical treatment for low-grade chondrosarcoma?
A) Chemotherapy
B) Radiation therapy
C) Surgical resection
D) Observation
Answer: C) Surgical resection

Which benign bone tumor is commonly found in the metaphysis of long bones and presents as a pedunculated lesion?
A) Enchondroma
B) Osteochondroma
C) Osteosarcoma
D) Chondrosarcoma
Answer: B) Osteochondroma

Which of the following features is more suggestive of a malignant bone tumor?
A) Well-circumscribed borders
B) Localized pain that worsens with activity
C) Rapid growth and soft tissue involvement
D) Night pain relieved by NSAIDs
Answer: C) Rapid growth and soft tissue involvement

What is the typical presentation of benign bone tumors?
A) Asymptomatic or mild symptoms
B) Severe pain and weight loss
C) Fever and fatigue
D) Night sweats and anemia
Answer: A) Asymptomatic or mild symptoms

Which of the following is a hallmark feature of malignant bone tumors?
A) Osteoid production
B) Slow growth
C) Invasion of surrounding tissues
D) Well-defined sclerotic borders
Answer: C) Invasion of surrounding tissues

Which tumor is considered malignant and characterized by the production of cartilage?
A) Osteochondroma
B) Chondrosarcoma
C) Giant cell tumor
D) Osteoid osteoma
Answer: B) Chondrosarcoma

What is the most common site for osteosarcoma?
A) Spine
B) Pelvis
C) Distal femur
D) Skull
Answer: C) Distal femur

Which benign tumor is commonly associated with nocturnal pain relieved by NSAIDs?
A) Osteoid osteoma
B) Osteosarcoma
C) Ewing sarcoma
D) Chondrosarcoma
Answer: A) Osteoid osteoma

What is the main difference between benign and malignant bone tumors on histopathology?
A) Presence of nuclear pleomorphism and mitotic figures in malignant tumors
B) Benign tumors show extensive necrosis
C) Benign tumors invade surrounding tissues
D) Malignant tumors do not form osteoid
Answer: A) Presence of nuclear pleomorphism and mitotic figures in malignant tumors

Which tumor commonly occurs in the epiphysis of long bones and is benign?
A) Osteochondroma
B) Chondrosarcoma
C) Giant cell tumor
D) Osteosarcoma
Answer: C) Giant cell tumor

Which of the following benign bone tumors typically resolves with skeletal maturity?
A) Osteoblastoma
B) Enchondroma
C) Non-ossifying fibroma
D) Osteoid osteoma
Answer: C) Non-ossifying fibroma

Which feature is most commonly associated with malignant bone tumors?
A) Lack of growth after puberty
B) Expansile, sclerotic lesions
C) Involvement of surrounding soft tissues
D) Well-defined borders
Answer: C) Involvement of surrounding soft tissues

What is the preferred diagnostic method to confirm the nature of a bone tumor?
A) X-ray
B) MRI
C) Biopsy
D) CT scan
Answer: C) Biopsy

Which benign tumor is typically associated with multiple hereditary exostoses?
A) Enchondroma
B) Osteoid osteoma
C) Osteochondroma
D) Fibrous dysplasia
Answer: C) Osteochondroma

Which malignant tumor often presents in the pelvis and shoulder girdle?
A) Ewing sarcoma
B) Chondrosarcoma
C) Osteosarcoma
D) Osteochondroma
Answer: B) Chondrosarcoma

Which of the following is a characteristic feature of osteochondromas?
A) Sessile or pedunculated bony growths
B) Malignant transformation in early stages
C) Arises in the epiphysis of long bones
D) Infiltrates surrounding tissues
Answer: A) Sessile or pedunculated bony growths

Which tumor has a “soap-bubble” appearance on radiographs?
A) Osteosarcoma
B) Ewing sarcoma
C) Giant cell tumor
D) Osteoid osteoma
Answer: C) Giant cell tumor

Which bone tumor is most likely to occur in the pelvis, ribs, and shoulder girdle?
A) Osteosarcoma
B) Ewing sarcoma
C) Chondrosarcoma
D) Osteoid osteoma
Answer: C) Chondrosarcoma

Which bone tumor has a higher likelihood of metastasis in older adults?
A) Osteoid osteoma
B) Chondrosarcoma
C) Non-ossifying fibroma
D) Osteochondroma
Answer: B) Chondrosarcoma

Which benign bone tumor is often asymptomatic and discovered incidentally on imaging?
A) Osteosarcoma
B) Osteochondroma
C) Ewing sarcoma
D) Chondrosarcoma
Answer: B) Osteochondroma

 

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