Bone Tumors MCQs

By: Prof. Dr. Fazal Rehman | Last updated: September 28, 2024

What is the most common primary bone tumor in adults? A) Osteosarcoma B) Chondrosarcoma C) Multiple myeloma D) Ewing sarcoma Answer: C) Multiple myeloma Which of the following is a benign bone tumor? A) Osteosarcoma B) Osteoid osteoma C) Chondrosarcoma D) Ewing sarcoma Answer: B) Osteoid osteoma What is the hallmark radiological feature of osteosarcoma? A) Onion-skin appearance B) Codman’s triangle C) Ground-glass appearance D) Sunburst pattern Answer: D) Sunburst pattern Which bone tumor is most commonly found in the metaphysis of long bones? A) Osteosarcoma B) Ewing sarcoma C) Chondrosarcoma D) Giant cell tumor Answer: A) Osteosarcoma Which age group is most commonly affected by Ewing sarcoma? A) Children and adolescents B) Middle-aged adults C) Elderly D) Infants Answer: A) Children and adolescents What is the primary site for metastasis of osteosarcoma? A) Brain B) Liver C) Lungs D) Kidneys Answer: C) Lungs What is a common symptom of bone tumors? A) Weight gain B) Bone pain C) Frequent infections D) Skin rashes Answer: B) Bone pain Which tumor has a characteristic “onion-skin” periosteal reaction on X-ray? A) Osteosarcoma B) Chondrosarcoma C) Ewing sarcoma D) Giant cell tumor Answer: C) Ewing sarcoma Which of the following is a primary malignant bone tumor? A) Osteochondroma B) Chondroma C) Osteosarcoma D) Osteoid osteoma Answer: C) Osteosarcoma Which tumor is typically located in the epiphysis of long bones? A) Osteosarcoma B) Giant cell tumor C) Chondrosarcoma D) Ewing sarcoma Answer: B) Giant cell tumor Which of the following bone tumors is associated with a genetic mutation? A) Osteoid osteoma B) Osteosarcoma C) Chondrosarcoma D) Osteochondroma Answer: B) Osteosarcoma Which bone tumor is known for producing cartilage matrix? A) Osteosarcoma B) Chondrosarcoma C) Ewing sarcoma D) Giant cell tumor Answer: B) Chondrosarcoma What is the preferred treatment for benign bone tumors? A) Chemotherapy B) Radiation therapy C) Surgical excision D) Immunotherapy Answer: C) Surgical excision Which imaging technique is most useful in evaluating bone tumors? A) Ultrasound B) X-ray C) MRI D) PET scan Answer: C) MRI Which tumor is more likely to occur in the pelvis and shoulder? A) Osteosarcoma B) Chondrosarcoma C) Ewing sarcoma D) Giant cell tumor Answer: B) Chondrosarcoma What is the most common symptom of a giant cell tumor? A) Joint instability B) Localized pain and swelling C) Fatigue D) Fever Answer: B) Localized pain and swelling What is the first-line treatment for osteosarcoma? A) Radiation B) Chemotherapy and surgery C) Hormonal therapy D) Antibiotics Answer: B) Chemotherapy and surgery Which benign bone tumor is commonly associated with night pain relieved by NSAIDs? A) Osteoid osteoma B) Chondroblastoma C) Fibrous dysplasia D) Aneurysmal bone cyst Answer: A) Osteoid osteoma Which tumor is characterized by aggressive local growth and potential metastasis to the lungs? A) Osteoid osteoma B) Giant cell tumor C) Ewing sarcoma D) Chondrosarcoma Answer: B) Giant cell tumor What is the typical age group affected by osteochondroma? A) Infants B) Adolescents and young adults C) Middle-aged adults D) Elderly Answer: B) Adolescents and young adults Which of the following is a rare benign tumor that occurs in the skull or spine? A) Osteoblastoma B) Ewing sarcoma C) Chondrosarcoma D) Osteoid osteoma Answer: A) Osteoblastoma What is the gold standard for diagnosing bone tumors? A) X-ray B) MRI C) Bone biopsy D) CT scan Answer: C) Bone biopsy Which tumor is known to produce a “soap bubble” appearance on X-ray? A) Giant cell tumor B) Osteosarcoma C) Chondrosarcoma D) Osteoid osteoma Answer: A) Giant cell tumor Which tumor is commonly associated with pathologic fractures? A) Osteosarcoma B) Chondroma C) Ewing sarcoma D) Giant cell tumor Answer: D) Giant cell tumor Which type of bone tumor commonly metastasizes to the lungs and is highly aggressive? A) Osteoid osteoma B) Osteosarcoma C) Enchondroma D) Osteochondroma Answer: B) Osteosarcoma Which tumor is primarily treated with curettage and bone grafting? A) Chondrosarcoma B) Osteosarcoma C) Giant cell tumor D) Ewing sarcoma Answer: C) Giant cell tumor Which of the following is a primary bone cancer that typically affects younger patients? A) Multiple myeloma B) Osteosarcoma C) Chondrosarcoma D) Metastatic carcinoma Answer: B) Osteosarcoma What type of tumor is often described as “moth-eaten” on radiographs? A) Ewing sarcoma B) Osteosarcoma C) Chondrosarcoma D) Osteochondroma Answer: A) Ewing sarcoma Which genetic condition is associated with multiple osteochondromas? A) Neurofibromatosis B) Ollier disease C) Hereditary multiple exostoses D) Marfan syndrome Answer: C) Hereditary multiple exostoses What is the typical age of onset for osteosarcoma? A) 10-20 years B) 30-40 years C) 50-60 years D) 70-80 years Answer: A) 10-20 years Which type of bone tumor is least likely to be malignant? A) Osteosarcoma B) Chondrosarcoma C) Osteochondroma D) Ewing sarcoma Answer: C) Osteochondroma Which tumor is characterized by a central nidus surrounded by sclerosis? A) Osteoid osteoma B) Ewing sarcoma C) Osteosarcoma D) Chondrosarcoma Answer: A) Osteoid osteoma Which type of bone tumor is associated with a poor prognosis due to its aggressive nature and high rate of metastasis? A) Osteosarcoma B) Osteochondroma C) Osteoid osteoma D) Enchondroma Answer: A) Osteosarcoma Which tumor is more likely to be found in the diaphysis of long bones? A) Ewing sarcoma B) Osteosarcoma C) Giant cell tumor D) Chondrosarcoma Answer: A) Ewing sarcoma What is the most common treatment for chondrosarcoma? A) Chemotherapy B) Radiation therapy C) Surgical resection D) Immunotherapy Answer: C) Surgical resection Which imaging modality is most sensitive for detecting bone marrow involvement in tumors? A) X-ray B) MRI C) CT scan D) Ultrasound Answer: B) MRI Which bone tumor is often associated with pain at night and relief with aspirin? A) Osteoid osteoma B) Osteosarcoma C) Chondrosarcoma D) Ewing sarcoma Answer: A) Osteoid osteoma What is the treatment approach for benign osteochondromas? A) Chemotherapy B) Radiation therapy C) Observation or surgical removal if symptomatic D) Bone marrow transplant Answer: C) Observation or surgical removal if symptomatic Which of the following bone tumors can arise from cartilage? A) Osteosarcoma B) Ewing sarcoma C) Chondrosarcoma D) Giant cell tumor Answer: C) Chondrosarcoma What is the typical radiographic appearance of osteochondroma? A) Pedunculated or sessile lesion B) Lytic lesion with sclerotic borders C) Onion-skin periosteal reaction D) Ground-glass appearance Answer: A) Pedunculated or sessile lesion Which bone tumor is more common in the vertebrae? A) Osteosarcoma B) Osteoblastoma C) Chondrosarcoma D) Giant cell tumor Answer: B) Osteoblastoma Which tumor is more commonly found in the pelvis, ribs, and femur? A) Osteosarcoma B) Chondrosarcoma C) Ewing sarcoma D) Osteoid osteoma Answer: B) Chondrosarcoma What is a common complication of untreated bone tumors? A) Skin rash B) Pathological fractures C) Hypercalcemia D) Osteoporosis Answer: B) Pathological fractures Which bone tumor often presents with localized swelling and tenderness? A) Osteoid osteoma B) Ewing sarcoma C) Osteochondroma D) Chondrosarcoma Answer: B) Ewing sarcoma Which bone tumor is associated with the production of osteoid? A) Osteosarcoma B) Chondrosarcoma C) Giant cell tumor D) Ewing sarcoma Answer: A) Osteosarcoma What is the typical histological finding in Ewing sarcoma? A) Spindle-shaped cells B) Small, round blue cells C) Cartilaginous matrix D) Osteoid deposition Answer: B) Small, round blue cells Which bone tumor is characterized by a mix of fibrous and osseous tissue? A) Fibrous dysplasia B) Osteochondroma C) Osteosarcoma D) Giant cell tumor Answer: A) Fibrous dysplasia  

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