Tuberculosis of the bone (Pott’s disease) MCQs

By: Prof. Dr. Fazal Rehman | Last updated: September 28, 2024

What is Pott’s disease? A) Tuberculosis of the lungs B) Tuberculosis of the bones and joints C) Tuberculosis of the spine D) Tuberculosis of the skin Answer: C) Tuberculosis of the spine Which part of the spine is most commonly affected by Pott’s disease? A) Cervical spine B) Thoracic spine C) Lumbar spine D) Sacral spine Answer: B) Thoracic spine What is a common symptom of Pott’s disease? A) Joint swelling B) Back pain C) Shortness of breath D) Skin rash Answer: B) Back pain What radiological finding is characteristic of Pott’s disease? A) Osteophyte formation B) Compression fractures C) Vertebral body destruction D) Scoliosis Answer: C) Vertebral body destruction What is the primary causative organism of Pott’s disease? A) Streptococcus pneumoniae B) Mycobacterium tuberculosis C) Staphylococcus aureus D) Escherichia coli Answer: B) Mycobacterium tuberculosis Which diagnostic test is essential for confirming Pott’s disease? A) X-ray B) MRI C) CT scan D) Tuberculin skin test Answer: B) MRI What complication can arise from untreated Pott’s disease? A) Improved mobility B) Spinal deformities C) Decreased infection risk D) Joint flexibility Answer: B) Spinal deformities In patients with Pott’s disease, what type of abscess can develop? A) Epidural abscess B) Subdural abscess C) Intra-articular abscess D) Cerebral abscess Answer: A) Epidural abscess Which demographic is most at risk for developing Pott’s disease? A) Young athletes B) Elderly individuals C) Immunocompromised patients D) Pregnant women Answer: C) Immunocompromised patients What is the standard treatment for Pott’s disease? A) Surgery only B) Antibiotics only C) A combination of antibiotics and surgery D) Bed rest Answer: C) A combination of antibiotics and surgery Which symptom is associated with advanced Pott’s disease? A) Fever and chills B) Increased appetite C) Weight gain D) Excessive sleep Answer: A) Fever and chills What role does the tuberculin skin test play in diagnosing Pott’s disease? A) It is definitive for diagnosis B) It indicates exposure to tuberculosis C) It rules out Pott’s disease D) It assesses spinal alignment Answer: B) It indicates exposure to tuberculosis What imaging technique can help visualize soft tissue involvement in Pott’s disease? A) X-ray B) CT scan C) Ultrasound D) MRI Answer: D) MRI What is a common complication of spinal tuberculosis? A) Osteoarthritis B) Kyphosis C) Scoliosis D) Bursitis Answer: B) Kyphosis What can happen if Pott’s disease is left untreated? A) Spontaneous recovery B) Increased physical activity C) Progression to paraplegia D) Enhanced bone density Answer: C) Progression to paraplegia Which laboratory test is often elevated in Pott’s disease? A) Complete blood count (CBC) B) Liver function tests C) Serum electrolytes D) Thyroid function tests Answer: A) Complete blood count (CBC) Which treatment option is NOT typically used for Pott’s disease? A) Antitubercular medications B) Non-steroidal anti-inflammatory drugs (NSAIDs) C) Chemotherapy D) Surgery Answer: C) Chemotherapy What is the primary goal of treatment for Pott’s disease? A) Pain management B) Complete eradication of Mycobacterium tuberculosis C) Prevention of spinal deformities D) All of the above Answer: D) All of the above Which of the following is a late complication of Pott’s disease? A) Localized swelling B) Spinal instability C) Fever D) Headache Answer: B) Spinal instability What type of abscess is often associated with Pott’s disease? A) Periosteal abscess B) Cold abscess C) Purulent abscess D) Fungal abscess Answer: B) Cold abscess Which factor can increase the risk of developing Pott’s disease? A) Good nutrition B) Poor immune function C) Regular exercise D) Healthy lifestyle Answer: B) Poor immune function What is the typical duration of antitubercular therapy for Pott’s disease? A) 1-2 months B) 3-6 months C) 6-12 months D) 12-18 months Answer: C) 6-12 months Which symptom is NOT commonly associated with Pott’s disease? A) Nausea B) Night sweats C) Back pain D) Weight loss Answer: A) Nausea What is the role of surgery in Pott’s disease? A) It is rarely needed B) It is used only for cosmetic reasons C) It is required in all cases D) It can relieve spinal compression or deformities Answer: D) It can relieve spinal compression or deformities Which joint can be involved in Pott’s disease? A) Hip joint B) Knee joint C) Shoulder joint D) All of the above Answer: D) All of the above What is the mechanism of action of antitubercular drugs used in Pott’s disease? A) They inhibit protein synthesis B) They disrupt cell wall synthesis C) They block DNA synthesis D) They increase immune response Answer: B) They disrupt cell wall synthesis What does the term “gibbus” refer to in Pott’s disease? A) A type of joint deformity B) A hunchback deformity due to spinal collapse C) A specific laboratory finding D) A surgical procedure Answer: B) A hunchback deformity due to spinal collapse Which sign is characteristic of Pott’s disease on physical examination? A) Tenderness over the abdomen B) Point tenderness over the affected vertebrae C) Hyperreflexia in the lower limbs D) Joint effusion Answer: B) Point tenderness over the affected vertebrae Which population is particularly susceptible to Pott’s disease? A) Healthy adults B) Immunocompromised individuals C) Athletes D) Children Answer: B) Immunocompromised individuals Which of the following is a common diagnostic imaging technique for Pott’s disease? A) Ultrasound B) CT scan C) X-ray D) All of the above Answer: D) All of the above What is the common presenting complaint in patients with Pott’s disease? A) Abdominal pain B) Lower back pain C) Upper extremity weakness D) Severe headaches Answer: B) Lower back pain What is the significance of a cold abscess in Pott’s disease? A) It indicates a more severe infection B) It is a common benign finding C) It is a surgical emergency D) It suggests a chronic infection Answer: D) It suggests a chronic infection What type of fever is commonly seen in Pott’s disease? A) Intermittent fever B) Constant high fever C) Low-grade fever D) No fever Answer: C) Low-grade fever What is the relationship between Pott’s disease and HIV? A) HIV increases the risk of developing Pott’s disease B) Pott’s disease has no relationship with HIV C) Pott’s disease protects against HIV D) HIV prevents the progression of Pott’s disease Answer: A) HIV increases the risk of developing Pott’s disease Which of the following is a differential diagnosis for Pott’s disease? A) Osteosarcoma B) Multiple myeloma C) Lymphoma D) All of the above Answer: D) All of the above Which antitubercular drug is often used in the treatment of Pott’s disease? A) Ciprofloxacin B) Isoniazid C) Amoxicillin D) Azithromycin Answer: B) Isoniazid What is a long-term consequence of untreated Pott’s disease? A) Increased mobility B) Bone healing C) Spinal deformities D) Improved quality of life Answer: C) Spinal deformities How can Pott’s disease affect the neurological system? A) It does not affect the neurological system B) By causing neuropathy due to nerve compression C) By increasing muscle strength D) By enhancing reflexes Answer: B) By causing neuropathy due to nerve compression What type of hypersensitivity reaction is involved in the immune response to tuberculosis? A) Type I B) Type II C) Type III D) Type IV Answer: D) Type IV Which group of patients is most likely to develop Pott’s disease? A) Adolescents B) Middle-aged men C) Elderly women D) Young children Answer: B) Middle-aged men What is the purpose of a biopsy in suspected Pott’s disease? A) To rule out other infections B) To obtain a definitive diagnosis C) To assess treatment response D) To determine the need for surgery Answer: B) To obtain a definitive diagnosis What finding is NOT typical in imaging studies for Pott’s disease? A) Destruction of vertebrae B) Formation of new bone C) Presence of abscess D) Compression of the spinal cord Answer: B) Formation of new bone What is the common term for the curvature of the spine seen in Pott’s disease? A) Lordosis B) Scoliosis C) Kyphosis D) Rigor Answer: C) Kyphosis What demographic is most affected by Pott’s disease? A) Young adults B) Infants C) Older adults D) All ages equally Answer: C) Older adults Which of the following is an important aspect of managing Pott’s disease? A) Long-term immobilization B) Regular follow-up and imaging C) Immediate surgical intervention D) Use of only topical medications Answer: B) Regular follow-up and imaging How does Pott’s disease typically present in children? A) No symptoms B) Severe back pain and fever C) Joint swelling D) Skin lesions Answer: B) Severe back pain and fever Which lifestyle factor is associated with a higher risk of developing Pott’s disease? A) Regular exercise B) Poor nutrition C) High socioeconomic status D) Regular medical check-ups Answer: B) Poor nutrition  

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