Pediatric Endocrinology (hormonal disorders in children) MCQs

Pediatric Endocrinology MCQs

  1. Which condition is characterized by excessive thirst and frequent urination in children?
    a) Diabetes mellitus
    b) Cystic fibrosis
    c) Hypothyroidism
    d) Adrenal insufficiency

    Answer: a) Diabetes mellitus

  2. What is the most common cause of congenital hypothyroidism in newborns?
    a) Thyroid dysgenesis
    b) Autoimmune thyroiditis
    c) Iodine deficiency
    d) Pituitary dysfunction

    Answer: a) Thyroid dysgenesis

  3. Which condition presents with short stature and delayed puberty in children?
    a) Growth hormone deficiency
    b) Hyperthyroidism
    c) Cushing’s syndrome
    d) Diabetes insipidus

    Answer: a) Growth hormone deficiency

  4. What is the primary treatment for hyperthyroidism in children?
    a) Antithyroid medications
    b) Thyroid hormone replacement
    c) Surgery
    d) Radioactive iodine therapy

    Answer: a) Antithyroid medications

  5. Which condition is associated with excessive growth hormone production in children?
    a) Acromegaly
    b) Dwarfism
    c) Gigantism
    d) Addison’s disease

    Answer: c) Gigantism

  6. What is a common symptom of Addison’s disease in children?
    a) Hyperpigmentation
    b) Hypoglycemia
    c) Hyperglycemia
    d) Weight gain

    Answer: a) Hyperpigmentation

  7. Which of the following is a sign of hypoparathyroidism in children?
    a) Tetany
    b) Hypercalcemia
    c) Kidney stones
    d) Polyuria

    Answer: a) Tetany

  8. Which test is used to diagnose type 1 diabetes mellitus?
    a) Hemoglobin A1c
    b) Serum cortisol
    c) TSH levels
    d) Growth hormone stimulation test

    Answer: a) Hemoglobin A1c

  9. What is the most common cause of secondary adrenal insufficiency in children?
    a) Pituitary tumors
    b) Autoimmune adrenalitis
    c) Congenital adrenal hyperplasia
    d) Addison’s disease

    Answer: a) Pituitary tumors

  10. Which hormone is primarily elevated in children with congenital adrenal hyperplasia (CAH)?
    a) Cortisol
    b) Aldosterone
    c) Androgens
    d) Thyroxine

    Answer: c) Androgens

  11. A child with delayed growth and development, and a high TSH level likely has:
    a) Hypothyroidism
    b) Hyperthyroidism
    c) Growth hormone deficiency
    d) Cushing’s syndrome

    Answer: a) Hypothyroidism

  12. Which condition is associated with the excess production of cortisol in children?
    a) Cushing’s syndrome
    b) Addison’s disease
    c) Hyperthyroidism
    d) Hypoparathyroidism

    Answer: a) Cushing’s syndrome

  13. What is the main clinical feature of hyperparathyroidism in children?
    a) Hypercalcemia
    b) Hypoglycemia
    c) Hyperkalemia
    d) Hypocalcemia

    Answer: a) Hypercalcemia

  14. Which condition presents with early onset of secondary sexual characteristics in children?
    a) Precocious puberty
    b) Delayed puberty
    c) Turner syndrome
    d) Klinefelter syndrome

    Answer: a) Precocious puberty

  15. What is the primary diagnostic test for diagnosing diabetes insipidus in children?
    a) Water deprivation test
    b) Hemoglobin A1c
    c) Serum cortisol
    d) TSH levels

    Answer: a) Water deprivation test

  16. Which of the following conditions is associated with the presence of elevated serum insulin levels in children?
    a) Insulinoma
    b) Type 1 diabetes
    c) Type 2 diabetes
    d) Addison’s disease

    Answer: a) Insulinoma

  17. Which disorder is characterized by inadequate production of growth hormone?
    a) Dwarfism
    b) Gigantism
    c) Acromegaly
    d) Cushing’s syndrome

    Answer: a) Dwarfism

  18. What is a common symptom of hyperthyroidism in children?
    a) Weight loss
    b) Weight gain
    c) Constipation
    d) Bradycardia

    Answer: a) Weight loss

  19. Which condition is associated with a deficiency in aldosterone production?
    a) Addison’s disease
    b) Cushing’s syndrome
    c) Hyperaldosteronism
    d) Congenital adrenal hyperplasia

    Answer: a) Addison’s disease

  20. What is the main cause of congenital hypothyroidism in areas with adequate iodine intake?
    a) Thyroid dysgenesis
    b) Iodine deficiency
    c) Autoimmune thyroiditis
    d) Pituitary dysfunction

    Answer: a) Thyroid dysgenesis

  21. Which hormone is involved in the regulation of calcium levels in the blood?
    a) Parathyroid hormone
    b) Insulin
    c) Growth hormone
    d) Cortisol

    Answer: a) Parathyroid hormone

  22. Which test is used to evaluate the function of the adrenal glands?
    a) ACTH stimulation test
    b) TSH test
    c) Growth hormone stimulation test
    d) Insulin tolerance test

    Answer: a) ACTH stimulation test

  23. What is the most common cause of primary adrenal insufficiency in children?
    a) Autoimmune adrenalitis
    b) Pituitary tumors
    c) Congenital adrenal hyperplasia
    d) Adrenal tumors

    Answer: a) Autoimmune adrenalitis

  24. Which condition involves insufficient production of thyroid hormone and presents with developmental delay in children?
    a) Hypothyroidism
    b) Hyperthyroidism
    c) Cushing’s syndrome
    d) Precocious puberty

    Answer: a) Hypothyroidism

  25. Which medication is commonly used to treat type 1 diabetes mellitus?
    a) Insulin
    b) Metformin
    c) Sulfonylureas
    d) GLP-1 receptor agonists

    Answer: a) Insulin

  26. Which endocrine disorder is characterized by an enlarged thyroid gland in children?
    a) Goiter
    b) Addison’s disease
    c) Diabetes mellitus
    d) Hypoparathyroidism

    Answer: a) Goiter

  27. What is the primary treatment for congenital adrenal hyperplasia (CAH)?
    a) Glucocorticoid replacement therapy
    b) Insulin therapy
    c) Thyroid hormone replacement
    d) Calcium supplements

    Answer: a) Glucocorticoid replacement therapy

  28. Which condition is associated with the deficiency of growth hormone in children, leading to short stature?
    a) Growth hormone deficiency
    b) Gigantism
    c) Acromegaly
    d) Cushing’s syndrome

    Answer: a) Growth hormone deficiency

  29. What is a common finding in children with hyperthyroidism?
    a) Increased appetite
    b) Bradycardia
    c) Constipation
    d) Weight gain

    Answer: a) Increased appetite

  30. Which hormone is used to assess adrenal function in suspected cases of adrenal insufficiency?
    a) Cortisol
    b) Thyroxine
    c) Insulin
    d) Growth hormone

    Answer: a) Cortisol

  31. A child with an overactive thyroid gland is likely to have elevated levels of which hormone?
    a) Thyroxine
    b) Insulin
    c) Cortisol
    d) Aldosterone

    Answer: a) Thyroxine

  32. Which condition is characterized by early onset of sexual characteristics in girls before age 9?
    a) Precocious puberty
    b) Delayed puberty
    c) Turner syndrome
    d) Klinefelter syndrome

    Answer: a) Precocious puberty

  33. Which of the following conditions can cause secondary growth hormone deficiency in children?
    a) Pituitary tumors
    b) Hyperthyroidism
    c) Diabetes mellitus
    d) Addison’s disease

    Answer: a) Pituitary tumors

  34. Which test is used to evaluate thyroid function in children with suspected hypothyroidism?
    a) Thyroid function tests (TFTs)
    b) ACTH stimulation test
    c) Water deprivation test
    d) Growth hormone stimulation test

    Answer: a) Thyroid function tests (TFTs)

  35. What is the main clinical feature of type 2 diabetes in children?
    a) Insulin resistance
    b) Autoimmune destruction of beta cells
    c) Adrenal insufficiency
    d) Hyperthyroidism

    Answer: a) Insulin resistance

  36. Which of the following is a common complication of uncontrolled diabetes mellitus in children?
    a) Diabetic ketoacidosis
    b) Hypercalcemia
    c) Hypoglycemia
    d) Hyperthyroidism

    Answer: a) Diabetic ketoacidosis

  37. A child with excess cortisol production is most likely to present with:
    a) Weight gain and hypertension
    b) Weight loss and hyperkalemia
    c) Weight loss and hypoglycemia
    d) Weight gain and hypoglycemia

    Answer: a) Weight gain and hypertension

  38. Which of the following conditions can cause low blood glucose levels in children?
    a) Insulinoma
    b) Cushing’s syndrome
    c) Hyperthyroidism
    d) Growth hormone deficiency

    Answer: a) Insulinoma

  39. Which hormone deficiency is most likely to cause delayed puberty in children?
    a) Gonadotropins
    b) Cortisol
    c) Thyroxine
    d) Growth hormone

    Answer: a) Gonadotropins

  40. A child with a short stature and elevated growth hormone levels is likely suffering from:
    a) Gigantism
    b) Dwarfism
    c) Acromegaly
    d) Cushing’s syndrome

    Answer: a) Gigantism

  41. Which condition involves the autoimmune destruction of thyroid tissue leading to hypothyroidism?
    a) Hashimoto’s thyroiditis
    b) Graves’ disease
    c) Addison’s disease
    d) Diabetes mellitus

    Answer: a) Hashimoto’s thyroiditis

  42. What is the main treatment for hypothyroidism in children?
    a) Thyroid hormone replacement therapy
    b) Antithyroid medications
    c) Glucocorticoids
    d) Insulin therapy

    Answer: a) Thyroid hormone replacement therapy

  43. Which of the following tests is used to diagnose hyperparathyroidism?
    a) Serum calcium and parathyroid hormone levels
    b) Thyroid function tests
    c) Serum cortisol levels
    d) Insulin levels

    Answer: a) Serum calcium and parathyroid hormone levels

  44. A child with rapid weight gain, facial puffiness, and abdominal striae might be suffering from:
    a) Cushing’s syndrome
    b) Addison’s disease
    c) Hyperthyroidism
    d) Growth hormone deficiency

    Answer: a) Cushing’s syndrome

  45. Which condition is characterized by excessive production of aldosterone?
    a) Hyperaldosteronism
    b) Addison’s disease
    c) Cushing’s syndrome
    d) Congenital adrenal hyperplasia

    Answer: a) Hyperaldosteronism

  46. What is the primary cause of precocious puberty in girls?
    a) Central precocious puberty
    b) Congenital adrenal hyperplasia
    c) Hypogonadism
    d) Hyperthyroidism

    Answer: a) Central precocious puberty

  47. Which condition is associated with a deficiency in sex hormone production, leading to delayed sexual development in children?
    a) Klinefelter syndrome
    b) Turner syndrome
    c) Precocious puberty
    d) Cushing’s syndrome

    Answer: a) Klinefelter syndrome

  48. Which diagnostic test is used to assess the function of the pituitary gland?
    a) Growth hormone stimulation test
    b) Thyroid function tests
    c) Water deprivation test
    d) ACTH stimulation test

    Answer: a) Growth hormone stimulation test

  49. A child presenting with dehydration, hypernatremia, and polyuria is most likely suffering from:
    a) Diabetes insipidus
    b) Diabetes mellitus
    c) Hyperthyroidism
    d) Hypoparathyroidism

    Answer: a) Diabetes insipidus

  50. Which endocrine disorder is commonly associated with elevated levels of cortisol and presents with abdominal obesity, moon facies, and hypertension?
    a) Cushing’s syndrome
    b) Addison’s disease
    c) Hyperthyroidism
    d) Hypothyroidism

    Answer: a) Cushing’s syndrome