Benign vs malignant bone tumors MCQs

Which of the following is a characteristic of benign bone tumors? A) Slow growth B) Infiltrative growth C) Frequent metastasis D) Painful in early stages Answer: A) Slow growth What is the typical radiographic appearance of malignant bone tumors? A) Well-defined borders B) Sclerotic margins C) Lytic and destructive patterns D) Central calcifications Answer: C) Lytic and destructive patterns Which of the following is a benign bone tumor? A) Osteosarcoma B) Osteoid osteoma C) Chondrosarcoma D) Ewing sarcoma Answer: B) Osteoid osteoma What feature distinguishes malignant bone tumors from benign bone tumors? A) Pain at night B) Well-circumscribed margins C) Potential for metastasis D) Occurrence in adolescents Answer: C) Potential for metastasis Which of the following is most likely to metastasize to the lungs? A) Osteochondroma B) Osteosarcoma C) Osteoid osteoma D) Enchondroma Answer: B) Osteosarcoma What is the common age group affected by benign bone tumors? A) Infants B) Adolescents C) Middle-aged adults D) Elderly Answer: B) Adolescents Which benign bone tumor commonly affects the spine? A) Osteosarcoma B) Osteoblastoma C) Ewing sarcoma D) Chondrosarcoma Answer: B) Osteoblastoma Which malignant bone tumor is characterized by a “sunburst” pattern on X-ray? A) Osteosarcoma B) Chondrosarcoma C) Ewing sarcoma D) Giant cell tumor Answer: A) Osteosarcoma Which tumor is considered a benign cartilage-forming tumor? A) Chondrosarcoma B) Osteochondroma C) Ewing sarcoma D) Osteosarcoma Answer: B) Osteochondroma What is a distinguishing feature of giant cell tumors? A) They are benign but locally aggressive B) They metastasize frequently C) They occur in the diaphysis of long bones D) They are common in elderly patients Answer: A) They are benign but locally aggressive Which tumor type is typically well-circumscribed and non-invasive? A) Malignant B) Benign C) Both D) Neither Answer: B) Benign What is the primary treatment for benign bone tumors? A) Chemotherapy B) Radiation therapy C) Surgical excision D) Observation Answer: C) Surgical excision Which of the following is more likely to show periosteal reaction on imaging? A) Benign bone tumors B) Malignant bone tumors C) Both D) Neither Answer: B) Malignant bone tumors Which bone tumor is more common in children and adolescents? A) Osteosarcoma B) Chondrosarcoma C) Multiple myeloma D) Osteoid osteoma Answer: A) Osteosarcoma What is a typical characteristic of malignant bone tumors on MRI? A) Homogeneous appearance B) High signal intensity on T1 C) Soft tissue invasion D) Presence of calcifications Answer: C) Soft tissue invasion Which benign tumor commonly arises from cartilage and is often asymptomatic? A) Osteoid osteoma B) Chondroblastoma C) Enchondroma D) Osteosarcoma Answer: C) Enchondroma Which tumor type is more likely to present with a pathologic fracture? A) Benign B) Malignant C) Both D) Neither Answer: B) Malignant Which of the following is a common symptom of both benign and malignant bone tumors? A) Weight gain B) Bone pain C) Night sweats D) Hair loss Answer: B) Bone pain What is a hallmark feature of benign bone tumors on X-ray? A) Poorly defined margins B) Expansile but without cortical breach C) Soft tissue mass D) Infiltrative appearance Answer: B) Expansile but without cortical breach Which tumor type is associated with Codman’s triangle on X-ray? A) Benign tumors B) Malignant tumors C) Both D) Neither Answer: B) Malignant tumors Which bone tumor is considered benign and frequently found in the epiphysis of long bones? A) Osteosarcoma B) Ewing sarcoma C) Giant cell tumor D) Chondrosarcoma Answer: C) Giant cell tumor What is the typical treatment for low-grade chondrosarcoma? A) Chemotherapy B) Radiation therapy C) Surgical resection D) Observation Answer: C) Surgical resection Which benign bone tumor is commonly found in the metaphysis of long bones and presents as a pedunculated lesion? A) Enchondroma B) Osteochondroma C) Osteosarcoma D) Chondrosarcoma Answer: B) Osteochondroma Which of the following features is more suggestive of a malignant bone tumor? A) Well-circumscribed borders B) Localized pain that worsens with activity C) Rapid growth and soft tissue involvement D) Night pain relieved by NSAIDs Answer: C) Rapid growth and soft tissue involvement What is the typical presentation of benign bone tumors? A) Asymptomatic or mild symptoms B) Severe pain and weight loss C) Fever and fatigue D) Night sweats and anemia Answer: A) Asymptomatic or mild symptoms Which of the following is a hallmark feature of malignant bone tumors? A) Osteoid production B) Slow growth C) Invasion of surrounding tissues D) Well-defined sclerotic borders Answer: C) Invasion of surrounding tissues Which tumor is considered malignant and characterized by the production of cartilage? A) Osteochondroma B) Chondrosarcoma C) Giant cell tumor D) Osteoid osteoma Answer: B) Chondrosarcoma What is the most common site for osteosarcoma? A) Spine B) Pelvis C) Distal femur D) Skull Answer: C) Distal femur Which benign tumor is commonly associated with nocturnal pain relieved by NSAIDs? A) Osteoid osteoma B) Osteosarcoma C) Ewing sarcoma D) Chondrosarcoma Answer: A) Osteoid osteoma What is the main difference between benign and malignant bone tumors on histopathology? A) Presence of nuclear pleomorphism and mitotic figures in malignant tumors B) Benign tumors show extensive necrosis C) Benign tumors invade surrounding tissues D) Malignant tumors do not form osteoid Answer: A) Presence of nuclear pleomorphism and mitotic figures in malignant tumors Which tumor commonly occurs in the epiphysis of long bones and is benign? A) Osteochondroma B) Chondrosarcoma C) Giant cell tumor D) Osteosarcoma Answer: C) Giant cell tumor Which of the following benign bone tumors typically resolves with skeletal maturity? A) Osteoblastoma B) Enchondroma C) Non-ossifying fibroma D) Osteoid osteoma Answer: C) Non-ossifying fibroma Which feature is most commonly associated with malignant bone tumors? A) Lack of growth after puberty B) Expansile, sclerotic lesions C) Involvement of surrounding soft tissues D) Well-defined borders Answer: C) Involvement of surrounding soft tissues What is the preferred diagnostic method to confirm the nature of a bone tumor? A) X-ray B) MRI C) Biopsy D) CT scan Answer: C) Biopsy Which benign tumor is typically associated with multiple hereditary exostoses? A) Enchondroma B) Osteoid osteoma C) Osteochondroma D) Fibrous dysplasia Answer: C) Osteochondroma Which malignant tumor often presents in the pelvis and shoulder girdle? A) Ewing sarcoma B) Chondrosarcoma C) Osteosarcoma D) Osteochondroma Answer: B) Chondrosarcoma Which of the following is a characteristic feature of osteochondromas? A) Sessile or pedunculated bony growths B) Malignant transformation in early stages C) Arises in the epiphysis of long bones D) Infiltrates surrounding tissues Answer: A) Sessile or pedunculated bony growths Which tumor has a “soap-bubble” appearance on radiographs? A) Osteosarcoma B) Ewing sarcoma C) Giant cell tumor D) Osteoid osteoma Answer: C) Giant cell tumor Which bone tumor is most likely to occur in the pelvis, ribs, and shoulder girdle? A) Osteosarcoma B) Ewing sarcoma C) Chondrosarcoma D) Osteoid osteoma Answer: C) Chondrosarcoma Which bone tumor has a higher likelihood of metastasis in older adults? A) Osteoid osteoma B) Chondrosarcoma C) Non-ossifying fibroma D) Osteochondroma Answer: B) Chondrosarcoma Which benign bone tumor is often asymptomatic and discovered incidentally on imaging? A) Osteosarcoma B) Osteochondroma C) Ewing sarcoma D) Chondrosarcoma Answer: B) Osteochondroma

Benign vs malignant bone tumors MCQs
By: Prof. Dr. Fazal Rehman | Last updated: September 28, 2024

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