Let me share with you a comparison between B Lymphocytes and T Lymphocytes.
| Aspect | B- Lymphocytes | T- Lymphocytes |
| Production | Produce and mature in the bone marrow. | Produce in the bone marrow but mature in the thymus. |
| Activation | Activated by direct contact with antigens or through signals from helper T cells. | Activated by antigens presented on the surface of antigen-presenting cells (APCs), with the help of helper T cells. |
| Antigen Receptors | BCRs receptors present on the surface of B cells, which recognize antigens directly. | TCRs receptors are present on the surface of T cells which recognize antigens |
| Types | · B memory cells · B plasma cells · B regulatory cells | · Helper T cells (CD4+) · Cytotoxic T cells (CD8+) · Regulatory T cells (Tregs) |
| Functions | · B cells can differentiate into plasma cells, producing antibodies that neutralize or tag pathogens for destruction. | · T cells can directly kill infected cells (cytotoxic T cells), · Helps to activate other immune cells (helper T cells) · Regulate immune responses (regulatory T cells). |
| Role in Immune Response | Primary role is in humoral immunity, involving the production of antibodies. | Play roles in cell-mediated immunity (cytotoxic T cells) and help coordinate immune responses (helper T cells). |