Rheumatology MCQs

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1. The most common autoimmune disease worldwide is:



2. Morning stiffness lasting more than 1 hour is characteristic of:



3. The most specific antibody for rheumatoid arthritis is:



4. Swan-neck deformity is seen in:



5. The hallmark radiological finding in rheumatoid arthritis is:



6. The most common extra-articular manifestation of rheumatoid arthritis is:



7. Which HLA type is strongly associated with ankylosing spondylitis?



8. Bamboo spine appearance is a feature of:



9. Schober’s test is used in the diagnosis of:



10. Uveitis is commonly associated with:



11. The butterfly rash is seen in:



12. The most specific antibody for systemic lupus erythematosus (SLE) is:



13. Libman-Sacks endocarditis is associated with:



14. Raynaud’s phenomenon is most commonly seen in:



15. Sclerodactyly is a feature of:



16. CREST syndrome includes all except:



17. Which antibody is highly specific for scleroderma?



18. The most common cause of acute monoarthritis in adults is:



19. Podagra refers to involvement of:



20. Tophi are deposits of:



21. Which crystals are negatively birefringent under polarized light?



22. Pseudogout is caused by deposition of:



23. Chondrocalcinosis is seen in:



24. The most common joint affected in osteoarthritis is:



25. Heberden’s nodes are seen in:



26. Bouchard’s nodes occur at:



27. Pencil-in-cup deformity on X-ray is typical of:



28. Dactylitis (“sausage digit”) is seen in:



29. The most common systemic vasculitis in adults is:



30. Polymyalgia rheumatica is strongly associated with:



31. A patient with temporal headache, jaw claudication, and vision loss likely has:



32. Polyarteritis nodosa is associated with:



33. Wegener’s granulomatosis is associated with:



34. Churg-Strauss syndrome is associated with:



35. Polymyositis primarily affects:



36. Heliotrope rash is seen in:



37. Gottron’s papules are diagnostic of:



38. Which antibody is associated with dermatomyositis and polymyositis?



39. Sjögren’s syndrome is characterized by:



40. The most specific antibody for Sjögren’s syndrome is:



41. Felty’s syndrome is a triad of:



42. Still’s disease is a subtype of:



43. The gold standard test for diagnosing gout is:



44. Allopurinol is used for:



45. Colchicine is mainly used in:



46. Methotrexate is the first-line DMARD for:



47. Hydroxychloroquine is especially useful in:



48. Biologics such as infliximab act against:



49. Which vasculitis affects large vessels?



50. Takayasu arteritis is also known as:



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