Comparison between Smooth endoplasmic reticulum and Rough endoplasmic reticulum

By: Prof. Dr. Fazal Rehman | Last updated: February 3, 2024

 

Let me share with you a comparison between Smooth endoplasmic reticulum and Rough endoplasmic reticulum.

Aspect            SER              RER
Full form ·        Smooth Endoplasmic Reticulum ·        Rough Endoplasmic Reticulum
Structure and Appearance ·        Lacks ribosomes on its surface, giving it a smooth appearance ·        Studded with ribosomes on its surface, giving it a rough or granular appearance.
Detoxification ·        Contains enzymes for detoxifying drugs and toxins ·        Not directly involved in drug detoxification and metabolism
Calcium Storage ·        Stores and regulates calcium ions in muscle cells ·        Not involved in calcium storage or regulation
Location ·        liver cells (hepatocytes)

·        adipocytes

·        Cells involved in lipid metabolism

·        Also found in various cell types, including cells that secrete proteins and enzymes, such as pancreatic cells.
Functions ·        Lipid metabolism

·        Detoxification

·        Calcium storage

·        Protein synthesis

·        Folding  and modification

·        Secretory protein production

 

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