Comparison between nucleotide and nucleoside

By: Prof. Dr. Fazal Rehman Shamil | Last updated: February 3, 2024

Let me share with you a comparison between nucleotide and nucleoside.

 

Aspect           Nucleotide          Nucleoside
Components·        Nitrogenous base

·        Pentose sugar (ribose or deoxyribose)

·        Phosphate group

·        Nitrogenous base

·        Pentose sugar (ribose or deoxyribose)

Structure·        Generally larger and more complex due to the phosphate group·        Have a smaller and simpler structure
Stability·        Less stable·        More stable
Phosphate group·        Present·        Absent
Role in building nucleic acids·        When linked together, they form DNA or RNA·        Not involved in forming DNA or RNA
Function·        Synthesis of DNA and RNA

·        Role in energy transfer and cell signaling

·        Serve as precursors for the synthesis of nucleotides and nucleic acids
Role in energy transfer·        Involved in energy transfer as ATP, GTP, etc.·        Not directly involved in energy transfer
Examples·        ATP

·        GTP

·        dTTP

·        Adenosine

·        Cytidine

·        Uridine