Comparison between Homozygous and Heterozygous

By: Prof. Dr. Fazal Rehman | Last updated: February 3, 2024

 

Let me share with you a comparison between Homozygous and Heterozygous.

Aspect Homozygous Heterozygous
Genetic makeup Two identical alleles for a specific gene e.g., AA or aa Two different alleles for a specific gene e.g., Aa
Dominance Both alleles express the same trait One allele may be dominant, while the other may be  recessive
Phenotype Typically expresses a specific trait related to the dominant allele May exhibit an intermediate trait related to both alleles
Genetic diversity Lower genetic diversity in the specific gene Higher genetic diversity in the specific gene
Inbreeding Prone to inbreeding depression when the allele is associated with harmful traits Less susceptible to inbreeding depression
Genetic Diseases More susceptible to recessive genetic diseases if the allele carries harmful mutations Less susceptible to recessive genetic diseases as the dominant allele often masks harmful mutations
Genetic Testing Easier to determine the genotype May require DNA sequencing or specific tests to identify the alleles
Probability of Passing on Alleles Always passes on the same allele to offspring Can pass on either of the two alleles to offspring with equal probability
Symbolization Homozygous dominant is represented as AA and homozygous recessive as aa Heterozygous is represented as Aa
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