Comparison between hepatitis A, B and  C

By: Prof. Dr. Fazal Rehman Shamil | Last updated: February 3, 2024

Let me share with you a comparison between hepatitis A, B and  C.

 

AspectHepatitis AHepatitis BHepatitis C
Causative agentRNA non enveloped virus DNA virusRNA enveloped virus
Virus familyPicornaviridaeHepadnaviridaeFlaviviridae
Known asInfectious HepatitisSerum HepatitisInfusion Hepatitis
Transmission·        Fecal-oral route

·        Often through contaminated food or water

·        Blood and bodily fluids

·        Sexual contact

·        perinatal transmission

·        Through direct contact with infected blood

·        Sharing of needles

·        Unsafe medical practices

Incubation periodApproximately 15-50 daysAverage 75 daysAbout 2 to 6 weeks
Symptoms·        Fever

·        Fatigue

·        Loss of appetite

·        Nausea

·        Abdominal pain

·        Jaundice (yellowing of the skin and eyes)

·        Fever

·        Fatigue

·        Loss of appetite

·        Nausea

·        Abdominal pain

·        Jaundice

·        Joint pain

·        Often asymptomatic in the acute phase

·        Chronic infection may lead to fatigue

·        Liver cirrhosis

·        Liver cancer

Chronic infectionRarely leads to chronic infectionCan lead to chronic infection in a significant number of casesBecomes chronic in the majority of cases
VaccinationAvailableAvailableNot available, but research is ongoing.
Treatment

 

 

 

·        Good hygiene

·        Sanitation

·        Vaccination

 

 

 

·        Vaccination,

·        safe sex practice

·        Avoiding sharing needles

 

 

·        Prevention of exposure to infected blood

·        Safe injection practices

·        Avoiding sharing of needles or personal items with infected individuals

Global impactHepatitis A is prevalent in areas with poor sanitation and hygiene practicesHepatitis B is a global health concern, with varying prevalence across regionsHepatitis C is a significant global health concern
Acute vs. ChronicAcute infectionBoth acute and chronic infectionsChronic infection
Diagnosis

 

·        Serological tests

·        Viral RNA detection

·        Serological tests

·        Viral DNA detection

·        Serological tests

·        Viral RNA detection