Comparison between hepatitis A, B and  C

By: Prof. Dr. Fazal Rehman | Last updated: February 3, 2024

Let me share with you a comparison between hepatitis A, B and  C.

 

Aspect Hepatitis A Hepatitis B Hepatitis C
Causative agent RNA non enveloped virus  DNA virus RNA enveloped virus
Virus family Picornaviridae Hepadnaviridae Flaviviridae
Known as Infectious Hepatitis Serum Hepatitis Infusion Hepatitis
Transmission ·        Fecal-oral route

·        Often through contaminated food or water

·        Blood and bodily fluids

·        Sexual contact

·        perinatal transmission

·        Through direct contact with infected blood

·        Sharing of needles

·        Unsafe medical practices

Incubation period Approximately 15-50 days Average 75 days About 2 to 6 weeks
Symptoms ·        Fever

·        Fatigue

·        Loss of appetite

·        Nausea

·        Abdominal pain

·        Jaundice (yellowing of the skin and eyes)

·        Fever

·        Fatigue

·        Loss of appetite

·        Nausea

·        Abdominal pain

·        Jaundice

·        Joint pain

·        Often asymptomatic in the acute phase

·        Chronic infection may lead to fatigue

·        Liver cirrhosis

·        Liver cancer

Chronic infection Rarely leads to chronic infection Can lead to chronic infection in a significant number of cases Becomes chronic in the majority of cases
Vaccination Available Available Not available, but research is ongoing.
Treatment

 

 

 

·        Good hygiene

·        Sanitation

·        Vaccination

 

 

 

·        Vaccination,

·        safe sex practice

·        Avoiding sharing needles

 

 

·        Prevention of exposure to infected blood

·        Safe injection practices

·        Avoiding sharing of needles or personal items with infected individuals

Global impact Hepatitis A is prevalent in areas with poor sanitation and hygiene practices Hepatitis B is a global health concern, with varying prevalence across regions Hepatitis C is a significant global health concern
Acute vs. Chronic Acute infection Both acute and chronic infections Chronic infection
Diagnosis

 

·        Serological tests

·        Viral RNA detection

·        Serological tests

·        Viral DNA detection

·        Serological tests

·        Viral RNA detection

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