Comparison between antiseptics and disinfectants

By: Prof. Dr. Fazal Rehman Shamil | Last updated: February 3, 2024

Let me share with you a comparison between antiseptics and disinfectants.

 

AspectAntisepticsDisinfectants
IntroductionChemical agents that are applied to living tissues (skin, mucous membranes) to inhibit or destroy microorganisms.Chemical agents that are applied to inanimate surfaces, objects, or substances to reduce or eliminate microorganisms.
PurposeUsed to prevent or treat infections on living tissues, often on wounds, cuts, or other damaged skin areas.Used to reduce or eliminate the microbial load on surfaces, medical equipment, and the environment to prevent the spread of infections.
ConcentrationGenerally lower concentration compared to disinfectants.Typically higher concentration than antiseptics.
ToxicityDesigned to be less toxic to living tissues.May be more toxic as they are not intended for direct application to living tissues.
Duration of ContactIntended for short-term contact with living tissues.May require longer contact time with surfaces for effective disinfection.
Compatibility with TissuesCompatible with living tissues and designed to minimize irritation or damage.Not always compatible with living tissues and may cause irritation or damage.
Examples·        Hydrogen peroxide

·        Iodine-based solutions

·        Alcohols

·        Chlorhexidine

·        Bleach (sodium hypochlorite)

·        Quaternary ammonium compounds (quats)

·        Hydrogen peroxide

·        Phenolic compounds

Uses·        Used in medical settings for preoperative skin preparation

·        Wound care

·        General infection prevention on living tissues

·        Used for cleaning and disinfection of medical equipment, surfaces and the environment
Effect on microorganismsEffective against a broad spectrum of microorganisms, including bacteria, viruses, and fungi.Also effective against a broad spectrum of microbial loads on surfaces.