Comparison between nucleotide and nucleoside

By: Prof. Dr. Fazal Rehman | Last updated: February 3, 2024

Let me share with you a comparison between nucleotide and nucleoside.

 

Aspect            Nucleotide           Nucleoside
Components ·        Nitrogenous base

·        Pentose sugar (ribose or deoxyribose)

·        Phosphate group

·        Nitrogenous base

·        Pentose sugar (ribose or deoxyribose)

Structure ·        Generally larger and more complex due to the phosphate group ·        Have a smaller and simpler structure
Stability ·        Less stable ·        More stable
Phosphate group ·        Present ·        Absent
Role in building nucleic acids ·        When linked together, they form DNA or RNA ·        Not involved in forming DNA or RNA
Function ·        Synthesis of DNA and RNA

·        Role in energy transfer and cell signaling

·        Serve as precursors for the synthesis of nucleotides and nucleic acids
Role in energy transfer ·        Involved in energy transfer as ATP, GTP, etc. ·        Not directly involved in energy transfer
Examples ·        ATP

·        GTP

·        dTTP

·        Adenosine

·        Cytidine

·        Uridine

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