Comparison between DNA and Chromosomes

By: Prof. Dr. Fazal Rehman | Last updated: February 3, 2024

Let me share with you a comparison between DNA and Chromosomes.

Aspect         DNA Chromosomes
Introduction A long molecule that carries genetic information in the form of a double helix Thread-like structures made of DNA and associated proteins found in the cell’s nucleus
Occurrence Found in the cell nucleus, mitochondria and chloroplasts Located within the cell nucleus of eukaryotic organisms
Composition Composed of nucleotides (A, T, C, and G) that form base pairs (A-T and C-G) Composed of DNA molecules coiled around proteins, primarily histones
Function Carries genetic information and instructions for protein synthesis Carry and protect genetic information in a condensed and organized form
Number Typically, organisms have one or two copies of DNA per cell depending on ploidy (diploid or haploid) Typically, organisms have a set number of chromosomes, with variations among species; humans have 46 chromosomes (23 pairs)
Structure Double-stranded helix structure with a sugar-phosphate backbone and nitrogenous bases Consist of two sister chromatids held together by a centromere
Replication DNA replication occurs during the cell cycle to create two identical DNA molecules Chromosomes replicate during the S phase of the cell cycle
Packaging DNA is packaged into compact structures called chromosomes Chromosomes condense and coil during cell division
Inheritance DNA carries genetic information from one generation to the next through cell division and reproduction Chromosomes are passed from parent to offspring during sexual reproduction
Variation Mutations in DNA can result in genetic diversity and evolution Variations in chromosome number or structure can lead to genetic disorders
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