1. What is the primary clinical feature of rheumatoid arthritis?
a) Morning stiffness lasting more than one hour
b) Acute onset of joint pain
c) Predominantly affects large joints
d) Joint pain without morning stiffness
Answer: a) Morning stiffness lasting more than one hour
2. Which of the following lab tests is most specific for rheumatoid arthritis?
a) Erythrocyte sedimentation rate (ESR)
b) C-reactive protein (CRP)
c) Rheumatoid factor (RF)
d) Anti-citrullinated protein antibody (ACPA)
Answer: d) Anti-citrullinated protein antibody (ACPA)
3. Which medication is commonly used as a first-line disease-modifying anti-rheumatic drug (DMARD) in the treatment of rheumatoid arthritis?
a) Methotrexate
b) Prednisone
c) Ibuprofen
d) Hydroxychloroquine
Answer: a) Methotrexate
4. Which of the following is NOT a common feature of systemic lupus erythematosus (SLE)?
a) Butterfly rash
b) Discoid rash
c) Positive anti-DNA antibody test
d) High serum uric acid levels
Answer: d) High serum uric acid levels
5. In which condition would you expect to find a “sausage digit” or dactylitis?
a) Psoriatic arthritis
b) Gout
c) Osteoarthritis
d) Ankylosing spondylitis
Answer: a) Psoriatic arthritis
6. Which of the following is a classic radiological finding in ankylosing spondylitis?
a) Joint erosions
b) Bamboo spine
c) Subchondral cysts
d) Osteophytes
Answer: b) Bamboo spine
7. What is the primary treatment for acute gout attacks?
a) Methotrexate
b) Colchicine
c) Hydroxychloroquine
d) Methotrexate
Answer: b) Colchicine
8. Which condition is characterized by a positive anti-Smith antibody test?
a) Rheumatoid arthritis
b) Systemic lupus erythematosus
c) Sjögren’s syndrome
d) Scleroderma
Answer: b) Systemic lupus erythematosus
9. What is the main clinical feature distinguishing osteoarthritis from rheumatoid arthritis?
a) Symmetrical joint involvement
b) Joint inflammation and swelling
c) Asymmetrical joint involvement
d) Presence of morning stiffness
Answer: c) Asymmetrical joint involvement
10. Which of the following is a common complication of systemic sclerosis (scleroderma)?
a) Pulmonary fibrosis
b) Acute renal failure
c) Nephrotic syndrome
d) Hemophilia
Answer: a) Pulmonary fibrosis
