Molecular Genetics Past Papers


Subject: Molecular Genetics-II

Time Allowed: 15 Min

Total Marks: 10

NOTE: ATTEMPT THIS PAPER ON THIS QUESTION SHEET ONLY. Division of marks is given in front of each question. This Paper will be collected back after expiry of time limit mentioned above.


Part-I Encircle the correct option, each question carries equal marks. (10)

  1. Bonding between purines and pyrimidines of two strands of DNA is:

(a) Ionic bonding

(b) Hydrogen bonding

(c) Covalent bonding

(d) Vander wall forces

  1. It is highly variable protein among different organisms:

(a) H2

(b) H2A

(c) H2B

(d) H3

  1. Enzyme used in PCR Is:

(a) RNA polymerase

(b) Taq polymerase

(c) Helicase

(d) Primase

  1. Replication in which two original strands of DNA remain together (after serving as templates), as would the two newly synthesized strands:

(a) Semi conservative replication

(b) Conservative replication

(c) Dispersive replication

(d) all of the above

  1. Sequence of initiator (Int.) in case of Drosophilla is:

(a) GCC (G/T) (G/T) C

(b) GCA (G/T) T (T/C)

(c) GCA (G/T) T (T/C)

(d) GCC (G/T) T (T/C)

  1. Two regions in mRNA that are not translated:

(a) Initiation codon

(b) 5′ UTR

(c) 3′ UTR

(d) both (b) and (c)

  1. Splicing takes place in:

(a) Nucleus

(b) Nucleolus

(c) Cytoplasm

(d) All of the above

  1. Group of genes that are regulated together is called:

(a) Repressor

(b) Operator

(c) Operon

(d) Promoter

  1. The process in which mature mRNA make proteins is called:

(a) Replication

(b) Transcription

(c) Splicing

(d) Translation

  1. Transposable elements were first discovered in eukaryotic cells:

(a) Viral genome

(b) Maize

(c) Pea

(d) All of the above


Subject: Molecular Genetics-II

Time Allowed: 2 Hour 45 Min

Total Marks: 50



Part-II Give short answers, each question carries equal marks. (20)

Q#1: Differentiate between metacentric and telocentric chromosome.

Q#2: Write down the requirements for replication in Eukaryotes.

Q#3: Define topological domain.

Q#4: Differentiate between Core promotor elements and Proxima] promotor elements.

Q#5: What is Splisosome?

Q#6: Draw structure of tRNA.

Q#7: Discuss points of Watson and Crick model of DNA.

Q#8: Draw the structure of premature mRNA.

Q#9: Define Molecular Genetics.

Q#10: What is the function of Helicase?


Part-III Give detailed answers, each question carries equal marks. (30)

Q#1: Give a detailed account of Transcription in prokaryotes.

Q#2: Discuss Transposable elements in Eukaryotes in detail.

Q#3: Give a detailed account of Leader and Traiter sequence.