Hematology MCQs
- Which of the following is the most common type of leukemia in adults?
- A) Acute lymphoblastic leukemia (ALL)
- B) Chronic lymphocytic leukemia (CLL)
- C) Acute myeloid leukemia (AML)
- D) Chronic myeloid leukemia (CML)
Answer: B) Chronic lymphocytic leukemia (CLL)
- Which of the following is a hallmark finding in iron deficiency anemia?
- A) Elevated ferritin levels
- B) Decreased mean corpuscular volume (MCV)
- C) Increased reticulocyte count
- D) Elevated vitamin B12 levels
Answer: B) Decreased mean corpuscular volume (MCV)
- In which condition would you expect to find elevated levels of both prothrombin time (PT) and activated partial thromboplastin time (aPTT)?
- A) Hemophilia A
- B) Vitamin K deficiency
- C) Von Willebrand disease
- D) Deep vein thrombosis (DVT)
Answer: B) Vitamin K deficiency
- What is the primary treatment for sickle cell disease?
- A) Blood transfusion
- B) Hydroxyurea
- C) Iron chelation therapy
- D) Anticoagulants
Answer: B) Hydroxyurea
- Which of the following is a common complication of polycythemia vera?
- A) Thrombocytopenia
- B) Bleeding diathesis
- C) Gout
- D) Anemia
Answer: C) Gout
- Which of the following tests is used to monitor the effectiveness of heparin therapy?
- A) Prothrombin time (PT)
- B) Activated partial thromboplastin time (aPTT)
- C) International normalized ratio (INR)
- D) Fibrinogen level
Answer: B) Activated partial thromboplastin time (aPTT)
- Which genetic mutation is commonly associated with chronic myeloid leukemia (CML)?
- A) JAK2 mutation
- B) BCR-ABL fusion gene
- C) TP53 mutation
- D) BRCA1 mutation
Answer: B) BCR-ABL fusion gene
- What is the primary feature of disseminated intravascular coagulation (DIC)?
- A) Hypercoagulability leading to thrombosis
- B) Excessive bleeding due to consumption of clotting factors
- C) Elevated platelet count
- D) Isolated elevated PT with normal aPTT
Answer: B) Excessive bleeding due to consumption of clotting factors
- In a patient with acute myeloid leukemia (AML), which cytogenetic abnormality is often associated with a poor prognosis?
- A) t(15;17) translocation
- B) t(8;21) translocation
- C) Del(5q) deletion
- D) Monosomy 7
Answer: D) Monosomy 7
- Which condition is characterized by a reduction in the number of all three blood cell types: red blood cells, white blood cells, and platelets?
- A) Anemia
- B) Leukemia
- C) Pancytopenia
- D) Thrombocytopenia
Answer: C) Pancytopenia