Aspect | Thalassemia | Anemia |
Introduction | A group of inherited blood disorders affecting the production of hemoglobin | A condition characterized by a reduced number of red blood cells or a decrease in the amount of hemoglobin in the blood |
Causes | Genetic mutations that affects the synthesis of alpha or beta globin chains of hemoglobin | Nutritional deficiencies |
Types | · Alpha thalassemia · Beta thalassemia | · Iron-deficiency anemia · Vitamin-deficiency anemia |
Inheritance | Autosomal recessive inheritance pattern for most types | Can be inherited or acquired, with diverse inheritance patterns for different types |
Clinical Features | · Fatigue · weakness · pallor · jaundice · enlarged spleen · Bone deformities in severe cases | · Fatigue · weakness · Pallor · Shortness of breath · Dizziness |
Treatment | · Blood transfusions · Iron chelation therapy · Bone marrow transplant | · Dietary changes · Iron supplements |
Risk Factors | · Genetic factors and family history | · Age · Gender · Diet · Chronic diseases |
Prevalence | More prevalent in populations with a high degree of consanguinity (related marriages) | Anemia can occur in individuals of all ages and populations |
Difference between thalassemia and anemia
Let me share with you a difference between thalassemia and anemia.