Let me share with you a difference between monocytes and macrophages.
Aspect | Monocytes | Macrophages |
Introduction | A type of white blood cell (leukocyte) | A type of immune cell derived from monocytes |
Production | Produced in the bone marrow | Monocytes migrate to various tissues and differentiate into macrophages |
Circulation | Circulate in the bloodstream as part of white blood cells | Found in tissues, organs and lymphoid structures |
Nucleus | Large, kidney-shaped or oval nucleus | Large, irregular-shaped nucleus |
Antigen Presentation | Limited role in antigen presentation | Important in antigen presentation to activate T cells and initiate immune responses |
Presence | Present in the bloodstream and can migrate into tissues | Present in various tissues, where they perform tissue-specific functions |
Maturation Time | Have a relatively short lifespan in circulation of about 1-3 days | Can have a longer lifespan, ranging from several weeks to months, depending on the tissue environment |
Examples
| · Monocytes
| · Alveolar macrophages · Kupffer cells · Microglia |