Difference between gastrin and gastric juice

By: Prof. Dr. Fazal Rehman | Last updated: February 3, 2024

 

Let me share with you a difference between gastrin and gastric juice.

Aspect Gastrin Gastric Juice
Introduction Gastrin is a hormone produced by G cells in the stomach and duodenum Gastric juice is a digestive fluid secreted by gastric glands in the stomach lining
Release Released in response to the presence of food, especially proteins, in the stomach Released in response to the sight, smell, taste, or presence of food, triggering neural and hormonal signals
Function Stimulates the secretion of gastric juice and promotes gastric motility Gastric juice is a complex mixture that includes hydrochloric acid, pepsinogen, mucus and intrinsic factor; it aids in the digestion of food
Target cells/organs Acts on parietal cells in the stomach lining to stimulate acid secretion Secreted into the stomach lumen to mix with ingested food and initiate the digestion process
Regulation Regulated by neural and hormonal signals, including the presence of amino acids and peptides in the stomach Regulated by neural signals (vagus nerve) and hormonal signals (gastrin-releasing peptide, acetylcholine)
Effects on stomach Increases gastric motility and enhances the secretion of gastric juice Facilitates the breakdown of proteins into peptides and amino acids
Effects on acid production Stimulates parietal cells to release hydrochloric acid, which lowers the pH of the stomach Contributes to the acidic nature of gastric juice, which aids in the digestion of proteins
Associated diseases Zollinger-Ellison syndrome Imbalances lead to digestive disorders, such as peptic ulcers
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