Difference between antigen and antibody

By: Prof. Dr. Fazal Rehman Shamil | Last updated: February 3, 2024

Let me share with you a difference between antigen and antibody.

AspectAntigenAntibody
IntroductionAntigen is a foreign substance, often a protein that induces an immune response.Antibody is a proteins produced by the immune system in response to antigens
Category·        Proteins

·        Lipids

·        Carbohydrates

·        Nucleic acids

·        Proteins (immunoglobulins)
Origin·        Can be foreign (from pathogens)

·        Self (from the body’s own cells)

·        Produced by B cells
SpecificityCan be specific or nonspecific, depending on the type of antigenHighly specific as each antibody is designed to bind to a specific antigen
StructureDiverse structures based on the type of molecule (proteins, lipids, etc.)Y-shaped structure with two identical antigen-binding sites at the tips of the arms
Types·        Bacterial cell surface proteins

·        viral proteins

·        Pollen proteins

·        IgG

·        IgM

·        IgA

·        IgD

·        IgE

TransferInherited from both parents, with some degree of variationNot inherited but transferred from mother to baby through breast milk during breastfeeding