Comparison between Enzyme and a Catalyst

By: Prof. Dr. Fazal Rehman | Last updated: February 3, 2024

Let me share with you a comparison between Enzyme and a Catalyst.

Aspect           Enzymes            Catalysts
Definition ·        Biological molecules mostly proteins that act as catalysts in living cells. ·        Catalyst can be biological or inorganic that increases the rate of chemical reactions without being consumed in the process.
Specificity ·        Highly specific ·        Specific but they are not as specific as enzymes.
Substrates ·        Require specific substrates for catalyzing reactions. ·        Do not require specific substrates, but they can accelerate various reactions.
Regulation ·        Activity can be regulated by various mechanisms, including feedback inhibition and allosteric regulation. ·        Generally not regulated by cellular processes
Function in ·        Function within living organisms, typically in cells or within specific cellular organelles. ·        Various industrial processes

·        Chemical reactions outside organisms.

Specific Names ·        Enzymes are named systematically   according to the type of reaction they catalyze e.g. amylase

·        DNA polymerase

·        Catalysts are typically identified by the reaction they accelerate e.g., hydrogen peroxide catalyst
Effect on activation energy ·        Lower the activation energy required for reactions ·        Lower activation energy required for reactions, but to a lesser extent compared to enzymes.
·        Generally accelerates reaction rates but to a lesser extent compared to enzymes.
Speed of reaction ·        Often accelerates reaction rates by several orders of magnitude.
Enzyme-substrate complex formation ·        Enzymes form temporary complexes with substrates during reactions. ·        Catalysts do not typically form Specific complexes with substrates.
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