Difference between small intestine and large intestine

By: Prof. Dr. Fazal Rehman | Last updated: February 3, 2024

Let me share with you a difference between small intestine and large intestine.

Aspect Small Intestine Large Intestine
Length Small intestine is longer in length, typically around 20 feet in humans Large intestine is shorter in length, typically around 5 feet in humans
Diameter Smaller in diameter Larger in diameter
Segments ·        Duodenum

·        Jejunum

·        Ileum

·        Cecum

·        Colon

·        Rectum

Function Primary site for digestion and absorption of nutrients Absorption of water and electrolytes, formation of feces
Structures Small intestine contains villi and microvilli to increase surface area for absorption Large intestine has numerous pouches called haustra
Absorption Absorbs carbohydrates, proteins, fats, vitamins and minerals Absorbs water, electrolytes, and some vitamins
Enzymes Receives pancreatic enzymes and bile for further digestion Lacks digestive enzymes and relies on bacterial fermentation for certain processes
Motility Exhibits peristaltic movements to move chyme through its length Exhibits slow segmenting movements to facilitate water absorption and compaction of feces
Bacterial population Fewer resident bacteria Contains a significant population of resident bacteria
Water absorption Absorbs water along with nutrients Main site for the absorption of water
Transit time Faster transit time for chyme through the small intestine Slower transit time to allow for water absorption in the large intestine
Associated diseases ·        Celiac disease

·        Crohn’s disease

·        Irritable bowel syndrome (IBS) Adiverticulitis
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