Which of the following is the first complex of the Electron Transport Chain (ETC)?

By: Prof. Dr. Fazal Rehman | Last updated: February 3, 2024

 

Question:   Which of the following is the first complex of the Electron Transport Chain (ETC)?

A   Complex II
B    Complex IV
C    Complex I
D    Complex V

Answer:  Complex I

 

Name of ETC complex Location in the cell         Function
Complex I NADH dehydrogenase Inner mitochondrial membrane

 

 

 

 

 

 

 

 

 

·        Transfers electrons from NADH to ubiquinone (Coenzyme Q).

·        It also pumps protons (H+) across the membrane to establish the proton gradient.

Complex II Succinate dehydrogenase ·        Transfers electrons from succinate to Coenzyme Q.
Complex III Cytochrome bc1 complex ·        Transfers electrons from Coenzyme Q to cytochrome c.
Complex IV Cytochrome c oxidase ·        Facilitates the final transfer of electrons from cytochrome c to molecular oxygen (O2) which results in the production of water (H2O).

·        It also pumps protons (H+) across the membrane.

Complex V ATP synthase (F1Fo ATPase) ·        Uses the proton gradient established by the other complexes to produce ATP from ADP and Pi.
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