Question: Which of the following is the first step of glycolysis?
A Breakdown of glucose
B Phosphorylation of glucose
C Conversion of glucose to fructose
D Dehydrogenation of glucose
Answer: Phosphorylation of glucose
| Introduction |
Steps of glycolysis |
Enzyme involved
|
| · Glycolysis occurs in the cytoplasm of the cell, generating ATP through substrate-level phosphorylation.
· It is also known as E.M.P. pathway which stands for Embden – Meyerhof – Parnas Pathway.
· It was discovered by Gustav Embden, Otto Meyerhof, and Jakub Karol Parnas
|
Step 1: Phosphorylation of Glucose |
Hexokinase |
| Step 2: Isomerization Glucose-6-Phosphate |
Phosphoglucose isomerase |
|
Step 3: Second Phosphorylation |
Phosphofructokinase-1 |
|
Step 4: Cleavage of Fructose 1,6-Bisphosphate |
Aldolase |
|
Step 5: Isomerization of Dihydroxyacetone Phosphate
|
Triose phosphate isomerase |
|
Step 7: Substrate-Level Phosphorylation |
Phosphoglycerate kinase |
|
Step 8: Inter-Molecular Shift of Phosphate Group
|
Phosphoglycerate mutase |
|
Step 9: Dehydration |
Enolase |
|
Step 10: Conversion of Phosphoenolpyruvate to Pyruvate |
Pyruvate kinase |
