Which of the following is the first step of glycolysis?
Question: Which of the following is the first step of glycolysis?
A Breakdown of glucose
B Phosphorylation of glucose
C Conversion of glucose to fructose
D Dehydrogenation of glucose
Answer: Phosphorylation of glucose
| Introduction | Steps of glycolysis | Enzyme involved
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| · Glycolysis occurs in the cytoplasm of the cell, generating ATP through substrate-level phosphorylation.
· It is also known as E.M.P. pathway which stands for Embden – Meyerhof – Parnas Pathway. · It was discovered by Gustav Embden, Otto Meyerhof, and Jakub Karol Parnas
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Step 1: Phosphorylation of Glucose | Hexokinase |
| Step 2: Isomerization Glucose-6-Phosphate | Phosphoglucose isomerase | |
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Step 3: Second Phosphorylation |
Phosphofructokinase-1 | |
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Step 4: Cleavage of Fructose 1,6-Bisphosphate |
Aldolase | |
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Step 5: Isomerization of Dihydroxyacetone Phosphate
|
Triose phosphate isomerase | |
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Step 7: Substrate-Level Phosphorylation |
Phosphoglycerate kinase | |
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Step 8: Inter-Molecular Shift of Phosphate Group
|
Phosphoglycerate mutase | |
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Step 9: Dehydration |
Enolase |
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Step 10: Conversion of Phosphoenolpyruvate to Pyruvate |
Pyruvate kinase |