Which of the following is not the first line of defense?

Question:  Which of the following is not the first line of defense?

A   Skin

B    Tears

C   Saliva

D   Fever

Answer:  Fever

Aspect First Line of Defense Second Line of Defense
Function Provides immediate, non-specific protection against pathogens and foreign invaders. Acts as a rapid but non-specific response to infection when the first line is breached, and helps initiate the specific immune response.
Components of defense ·        Mucus membranes

·        Stomach acid

·        Saliva

·        Microbiome

·        Neutrophils

·        macrophages

·        Natural killer cells

·        Complement proteins

·        Inflammatory response

Specificity Non-specific Specific
Response Time Immediate Rapid
Effector Mechanisms Barriers and processes that prevent pathogens from entering the body or from causing harm. Phagocytosis (engulfing and destroying pathogens), inflammation, and activation of the complement system.
Adaptive Immunity Not part of the adaptive immune response, which is the third line of defense in the body. Initiates and coordinates the adaptive immune response when necessary.