QUESTION: Which vitamin deficiency causes mouth ulcers?
ANS:
- Vitamin B12 deficiency is the specific vitamin deficiency most commonly associated with mouth ulcers.
- Vitamin B12 is involved in DNA synthesis and cell division. Adequate B12 levels are necessary for the normal turnover and regeneration of the cells in the oral mucosa. A deficiency in B12 can impair this process, leading to thinning and vulnerability of the mucosal lining, making it more susceptible to ulcers.
- B12 deficiency can cause neurological symptoms, such as tingling or numbness in the mouth or tongue. These symptoms can lead to unintentional biting or injuring of the oral tissues, increasing the risk of mouth ulcers.
| Role of Vitamin B12 Deficiency in Mouth Ulcers |
| Cell Division and Regeneration |
| · Vitamin B12 is involved in DNA synthesis and cell division. · Deficiency can impair the normal turnover and regeneration of oral mucosal cells. |
| Neurological Effects |
| · B12 deficiency can cause neurological symptoms, such as tingling or numbness in the mouth or tongue. · These symptoms can lead to unintentional biting or injuring of the oral tissues, increasing the risk of mouth ulcers. |
| Weakened Immune Response |
| · Vitamin B12 is essential for the proper functioning of the immune system. · Deficiency can weaken the immune response, making the oral tissues more susceptible to infections and inflammation, contributing to mouth ulcers. |
| Vitamin Deficiency | Associated Condition | Symptom: Mouth Ulcers |
| Vitamin B12 | Pernicious anemia | Yes |
| Vitamin C | Scurvy | Yes |
| Iron | Iron deficiency anemia | Yes |
| Folate | Folate deficiency anemia | Yes |
| Zinc | Zinc deficiency | Yes |