Gout and other crystal arthropathies MCQs

By: Prof. Dr. Fazal Rehman Shamil | Last updated: September 28, 2024

What is gout primarily caused by?
A) Excessive uric acid production
B) Infection
C) Viral invasion
D) Autoimmune disorder
Answer: A) Excessive uric acid production

Which joint is most commonly affected by gout?
A) Shoulder
B) Knee
C) Big toe
D) Wrist
Answer: C) Big toe

What are the characteristic symptoms of a gout attack?
A) Gradual onset of pain
B) Sudden, severe pain, swelling, and redness
C) Chronic pain over weeks
D) Only joint stiffness
Answer: B) Sudden, severe pain, swelling, and redness

What is the role of uric acid in gout?
A) It is an essential nutrient
B) It causes joint inflammation when levels are elevated
C) It prevents arthritis
D) It has no effect on the body
Answer: B) It causes joint inflammation when levels are elevated

Which of the following foods should be limited to help manage gout?
A) Fruits and vegetables
B) Whole grains
C) Red meat and seafood
D) Low-fat dairy
Answer: C) Red meat and seafood

What is a common non-steroidal anti-inflammatory drug (NSAID) used to treat gout?
A) Acetaminophen
B) Aspirin
C) Indomethacin
D) Ibuprofen
Answer: C) Indomethacin

What is the first-line treatment for an acute gout attack?
A) Allopurinol
B) Colchicine
C) Methotrexate
D) Antibiotics
Answer: B) Colchicine

How does allopurinol help in the management of gout?
A) It reduces pain during attacks
B) It lowers uric acid levels in the blood
C) It prevents joint swelling
D) It promotes the excretion of uric acid
Answer: B) It lowers uric acid levels in the blood

Which crystal is commonly associated with gout?
A) Calcium phosphate
B) Urate
C) Hydroxyapatite
D) Struvite
Answer: B) Urate

What is the typical demographic most affected by gout?
A) Young children
B) Middle-aged and older men
C) Pregnant women
D) Athletes
Answer: B) Middle-aged and older men

What is the function of colchicine in gout management?
A) It reduces uric acid production
B) It alleviates pain and inflammation
C) It strengthens bones
D) It fights infections
Answer: B) It alleviates pain and inflammation

What test is often used to confirm the diagnosis of gout?
A) Blood glucose test
B) Synovial fluid analysis
C) MRI
D) X-ray
Answer: B) Synovial fluid analysis

Which of the following is NOT a common risk factor for developing gout?
A) Obesity
B) Excessive alcohol consumption
C) Sedentary lifestyle
D) High levels of physical activity
Answer: D) High levels of physical activity

What is the effect of dehydration on gout?
A) It reduces uric acid levels
B) It increases the risk of gout attacks
C) It has no effect
D) It alleviates symptoms
Answer: B) It increases the risk of gout attacks

In addition to gout, what other condition is associated with elevated uric acid levels?
A) Osteoporosis
B) Hyperuricemia
C) Osteoarthritis
D) Fibromyalgia
Answer: B) Hyperuricemia

Which joint disorder is characterized by the presence of calcium pyrophosphate crystals?
A) Gout
B) Psoriatic arthritis
C) Pseudogout
D) Osteoarthritis
Answer: C) Pseudogout

What is pseudogout primarily caused by?
A) Increased uric acid levels
B) Deposition of calcium pyrophosphate crystals
C) Viral infection
D) Bacterial infection
Answer: B) Deposition of calcium pyrophosphate crystals

How can lifestyle changes impact gout management?
A) They have no effect
B) They can help lower uric acid levels
C) They worsen the condition
D) They only improve joint mobility
Answer: B) They can help lower uric acid levels

What dietary modification is often recommended for gout patients?
A) Increase intake of sugary foods
B) Avoid high-purine foods
C) Consume more fatty foods
D) Limit vegetable intake
Answer: B) Avoid high-purine foods

Which medication is used to prevent gout attacks?
A) Colchicine
B) Allopurinol
C) NSAIDs
D) Corticosteroids
Answer: B) Allopurinol

What is the primary cause of hyperuricemia?
A) Increased renal excretion of uric acid
B) Increased dietary intake of purines
C) Decreased production of uric acid
D) Increased metabolism
Answer: B) Increased dietary intake of purines

What is the expected outcome of gout treatment?
A) Permanent cure
B) Control of symptoms and prevention of future attacks
C) Worsening of the disease
D) Complete removal of uric acid from the body
Answer: B) Control of symptoms and prevention of future attacks

What is a common side effect of long-term use of colchicine?
A) Weight gain
B) Gastrointestinal upset
C) Hair loss
D) Skin rash
Answer: B) Gastrointestinal upset

Which of the following can trigger a gout attack?
A) Stress
B) Sudden weight loss
C) Dehydration
D) All of the above
Answer: D) All of the above

Which joint is less commonly affected by gout?
A) Elbow
B) Ankle
C) Knee
D) Big toe
Answer: A) Elbow

What is a common misconception about gout?
A) It only affects older individuals
B) It is not a serious condition
C) It can be managed with lifestyle changes
D) It is a hereditary disease
Answer: B) It is not a serious condition

What is the effect of alcohol on gout?
A) It has no impact
B) It decreases uric acid levels
C) It can increase uric acid levels and trigger attacks
D) It improves joint function
Answer: C) It can increase uric acid levels and trigger attacks

Which type of crystal arthropathy involves urate crystals and typically affects middle-aged men?
A) Gout
B) Pseudogout
C) Osteoarthritis
D) Reactive arthritis
Answer: A) Gout

What is the usual duration of a gout attack?
A) Several days to weeks
B) A few hours
C) Only a few minutes
D) Indefinite
Answer: A) Several days to weeks

Which medication is commonly prescribed to lower uric acid levels over time?
A) Indomethacin
B) Allopurinol
C) Naproxen
D) Colchicine
Answer: B) Allopurinol

Which of the following is a sign of gout?
A) Joint warmth and swelling
B) Limited range of motion without pain
C) Joint deformity without pain
D) Soft tissue swelling without joint involvement
Answer: A) Joint warmth and swelling

What is the role of synovial fluid analysis in diagnosing gout?
A) To measure uric acid levels
B) To identify the presence of urate crystals
C) To assess joint range of motion
D) To detect infections
Answer: B) To identify the presence of urate crystals

How does obesity affect gout?
A) It has no effect
B) It can lower uric acid levels
C) It increases the risk of developing gout
D) It reduces inflammation
Answer: C) It increases the risk of developing gout

What is a common trigger for a gout attack?
A) High fluid intake
B) Stress and overexertion
C) Regular exercise
D) Adequate sleep
Answer: B) Stress and overexertion

What is the importance of patient education in managing gout?
A) It is unnecessary
B) It helps patients understand their condition and make lifestyle changes
C) It only focuses on medication adherence
D) It discourages treatment options
Answer: B) It helps patients understand their condition and make lifestyle changes

What is the effect of purine-rich foods on gout?
A) They lower uric acid levels
B) They have no effect on the body
C) They can raise uric acid levels and trigger attacks
D) They are essential for health
Answer: C) They can raise uric acid levels and trigger attacks

Which of the following conditions can be mistaken for gout?
A) Osteoarthritis
B) Rheumatoid arthritis
C) Pseudogout
D) All of the above
Answer: D) All of the above

How do lifestyle modifications help in the management of gout?
A) They have no significant impact
B) They can lower uric acid levels and reduce attack frequency
C) They only improve joint mobility
D) They worsen the condition
Answer: B) They can lower uric acid levels and reduce attack frequency

What is the role of kidney function in gout?
A) It has no relevance
B) Poor kidney function can lead to increased uric acid levels
C) It helps in the absorption of uric acid
D) It prevents gout attacks
Answer: B) Poor kidney function can lead to increased uric acid levels

Which medication is contraindicated during an acute gout attack?
A) Colchicine
B) NSAIDs
C) Allopurinol
D) Corticosteroids
Answer: C) Allopurinol

What is the typical uric acid level that indicates hyperuricemia?
A) Above 3 mg/dL
B) Above 5 mg/dL
C) Above 7 mg/dL
D) Above 9 mg/dL
Answer: C) Above 7 mg/dL

Which of the following is an effective non-pharmacological approach to managing gout?
A) Staying hydrated
B) High-protein diet
C) Excessive alcohol consumption
D) Low-activity lifestyle
Answer: A) Staying hydrated

What does the presence of monosodium urate crystals in synovial fluid indicate?
A) Osteoarthritis
B) Gout
C) Rheumatoid arthritis
D) Pseudogout
Answer: B) Gout

What are the long-term effects of untreated gout?
A) Increased joint health
B) Chronic pain and joint damage
C) Improved mobility
D) No effect on health
Answer: B) Chronic pain and joint damage

What is the best time to take allopurinol for gout management?
A) In the morning
B) At night
C) With meals
D) Whenever symptoms occur
Answer: B) At night

What is a key feature of crystal-induced arthropathies like gout?
A) They are caused by autoimmune processes
B) They involve the deposition of crystals in joints
C) They do not cause inflammation
D) They are easily curable
Answer: B) They involve the deposition of crystals in joints

What is the significance of monitoring uric acid levels in gout patients?
A) It is not necessary
B) It helps to prevent future attacks and manage treatment
C) It only matters during acute attacks
D) It has no relevance to treatment outcomes
Answer: B) It helps to prevent future attacks and manage treatment

How does gout affect quality of life?
A) It has no impact
B) It can significantly impair daily activities and mental health
C) It improves physical fitness
D) It encourages social activities
Answer: B) It can significantly impair daily activities and mental health

What lifestyle change is recommended for patients with gout?
A) Increase red meat consumption
B) Stay hydrated and limit alcohol
C) Avoid all dairy products
D) Engage in high-impact exercise
Answer: B) Stay hydrated and limit alcohol

What is the recommended fluid intake for patients with gout?
A) 1-2 cups per day
B) At least 8-16 cups per day
C) No specific recommendation
D) Only during an acute attack
Answer: B) At least 8-16 cups per day

 

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