Antimicrobial Therapy MCQs

By: Prof. Dr. Fazal Rehman | Last updated: July 27, 2024

  1. Which class of antibiotics is primarily used to treat infections caused by Gram-positive bacteria?
    a) Penicillins
    b) Aminoglycosides
    c) Fluoroquinolones
    d) TetracyclinesAnswer: a) Penicillins
  2. Which antibiotic is known for its broad-spectrum activity, including effectiveness against both Gram-positive and Gram-negative bacteria?
    a) Vancomycin
    b) Amoxicillin
    c) Ciprofloxacin
    d) ErythromycinAnswer: c) Ciprofloxacin
  3. Which of the following antibiotics is a beta-lactamase inhibitor?
    a) Clavulanic acid
    b) Azithromycin
    c) Doxycycline
    d) RifampinAnswer: a) Clavulanic acid
  4. Which class of antibiotics inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit?
    a) Macrolides
    b) Aminoglycosides
    c) Cephalosporins
    d) FluoroquinolonesAnswer: b) Aminoglycosides
  5. Which antibiotic is often used as a last-resort treatment for methicillin-resistant Staphylococcus aureus (MRSA)?
    a) Vancomycin
    b) Penicillin
    c) Erythromycin
    d) LevofloxacinAnswer: a) Vancomycin
  6. What is the primary mechanism of action of fluoroquinolones?
    a) Inhibition of cell wall synthesis
    b) Inhibition of protein synthesis
    c) Inhibition of DNA gyrase and topoisomerase IV
    d) Inhibition of folic acid synthesisAnswer: c) Inhibition of DNA gyrase and topoisomerase IV
  7. Which of the following antibiotics is used to treat tuberculosis (TB)?
    a) Isoniazid
    b) Ciprofloxacin
    c) Azithromycin
    d) CephalexinAnswer: a) Isoniazid
  8. Which antibiotic is known for its association with the risk of tendon rupture, particularly in the elderly?
    a) Doxycycline
    b) Penicillin
    c) Ciprofloxacin
    d) VancomycinAnswer: c) Ciprofloxacin
  9. Which of the following is a common side effect of tetracycline antibiotics?
    a) Photosensitivity
    b) Nephrotoxicity
    c) Ototoxicity
    d) HepatotoxicityAnswer: a) Photosensitivity
  10. Which antibiotic is used to treat infections caused by anaerobic bacteria?
    a) Metronidazole
    b) Rifampin
    c) Amoxicillin
    d) GentamicinAnswer: a) Metronidazole
  11. Which class of antibiotics includes drugs like azithromycin and erythromycin?
    a) Macrolides
    b) Lincosamides
    c) Cephalosporins
    d) CarbapenemsAnswer: a) Macrolides
  12. What is the primary mechanism of action of sulfonamides?
    a) Inhibition of bacterial cell wall synthesis
    b) Inhibition of bacterial protein synthesis
    c) Inhibition of folic acid synthesis
    d) Inhibition of DNA replicationAnswer: c) Inhibition of folic acid synthesis
  13. Which antibiotic is commonly used to treat urinary tract infections (UTIs) due to its high renal concentration?
    a) Nitrofurantoin
    b) Vancomycin
    c) Doxycycline
    d) LevofloxacinAnswer: a) Nitrofurantoin
  14. Which antimicrobial agent is known to cause discoloration of teeth in children when used during tooth development?
    a) Tetracycline
    b) Penicillin
    c) Vancomycin
    d) RifampinAnswer: a) Tetracycline
  15. Which of the following drugs is a carbapenem antibiotic?
    a) Meropenem
    b) Ceftriaxone
    c) Azithromycin
    d) VancomycinAnswer: a) Meropenem
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