General Clinical Medicine MCQs

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1. Which of the following is the most common cause of iron deficiency anemia worldwide?



2. Which investigation is most sensitive for early detection of myocardial infarction?



3. Which of the following is the first-line drug in hypertension management?



4. Which electrolyte imbalance is commonly seen with loop diuretics?



5. The classic triad of meningitis includes:



6. The most common cause of peptic ulcer disease is:



7. The hallmark feature of nephrotic syndrome is:

9. The best initial management of anaphylaxis is:



10. The most common cause of community-acquired pneumonia is:



11. The gold standard investigation for pulmonary embolism is:



12. The “butterfly rash” on the face is typical of:



13. Which sign is most specific for appendicitis?



14. The most common cause of hypothyroidism worldwide is:



15. Which heart sound is associated with heart failure?



16. The drug of choice for status epilepticus is:



17. Which hormone is deficient in Addison’s disease?



18. The most common cause of cirrhosis in the world is:



19. Atrial fibrillation most commonly predisposes to:



20. Which vitamin deficiency causes scurvy?



21. The first-line treatment of type 2 diabetes mellitus is:



22. Which condition is associated with “cobblestone mucosa” on colonoscopy?



23. The most common cause of secondary hypertension is:



24. The hallmark sign of pericardial tamponade is:



25. The triad of polyuria, polydipsia, and polyphagia is seen in:



26. Which is the gold standard test for tuberculosis diagnosis?



27. The commonest cause of chronic liver disease in children is:



28. The hallmark sign of right-sided heart failure is:



29. The “honeycomb lung” appearance is seen in:



30. The triad of confusion, ataxia, and ophthalmoplegia indicates:



31. The most common cause of end-stage renal disease worldwide is:



32. Which heart murmur is described as “diastolic rumble with opening snap”?



33. Which electrolyte abnormality causes Trousseau’s and Chvostek’s signs?



34. The most common cause of upper GI bleeding is:



35. A patient with COPD is advised to avoid:



36. Which investigation confirms deep vein thrombosis (DVT)?



37. Which vitamin deficiency causes megaloblastic anemia?



38. Which autoimmune condition is associated with exophthalmos?



39. Which disease presents with Kayser-Fleischer rings in the eyes?



40. Which condition is diagnosed using the Schilling test?



41. The drug of choice for acute gout attack is:



42. Which murmur increases on standing and decreases on squatting?



43. The most common complication of diabetes mellitus is:



44. The hallmark feature of Parkinson’s disease is:



45. Which deficiency leads to beriberi?



46. The diagnostic test for Myasthenia Gravis is:



47. Which type of hepatitis is transmitted by contaminated water?



48. The commonest cause of death in myocardial infarction is:



49. Which type of hypersensitivity reaction is seen in bronchial asthma?



50. The diagnostic triad of asthma includes:



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