Antimicrobial Therapy MCQs

1. : Which class of antibiotics is primarily used to treat infections caused by Gram-positive bacteria?
(A) Penicillins
(B) Aminoglycosides
(C) Fluoroquinolones
(D) Tetracyclines

2. : Which antibiotic is known for its broad-spectrum activity, including effectiveness against both Gram-positive and Gram-negative bacteria?
(A) Vancomycin
(B) Amoxicillin
(C) Ciprofloxacin
(D) Erythromycin

3. : Which of the following antibiotics is a beta-lactamase inhibitor?
(A) Clavulanic acid
(B) Azithromycin
(C) Doxycycline
(D) Rifampin

4. : Which class of antibiotics inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit?
(A) Macrolides
(B) Aminoglycosides
(C) Cephalosporins
(D) Fluoroquinolones

5. : Which antibiotic is often used as a last-resort treatment for methicillin-resistant Staphylococcus aureus (MRSA)?
(A) Vancomycin
(B) Penicillin
(C) Erythromycin
(D) Levofloxacin

6. : What is the primary mechanism of action of fluoroquinolones?
(A) Inhibition of cell wall synthesis
(B) Inhibition of protein synthesis
(C) Inhibition of DNA gyrase and topoisomerase IV
(D) Inhibition of folic acid synthesis

7. : Which of the following antibiotics is used to treat tuberculosis (TB)?
(A) Isoniazid
(B) Ciprofloxacin
(C) Azithromycin
(D) Cephalexin

8. : Which antibiotic is known for its association with the risk of tendon rupture, particularly in the elderly?
(A) Doxycycline
(B) Penicillin
(C) Ciprofloxacin
(D) Vancomycin

9. : Which of the following is a common side effect of tetracycline antibiotics?
(A) Photosensitivity
(B) Nephrotoxicity
(C) Ototoxicity
(D) Hepatotoxicity

10. : Which antibiotic is used to treat infections caused by anaerobic bacteria?
(A) Metronidazole
(B) Rifampin
(C) Amoxicillin
(D) Gentamicin

11. : Which class of antibiotics includes drugs like azithromycin and erythromycin?
(A) Macrolides
(B) Lincosamides
(C) Cephalosporins
(D) Carbapenems

12. : What is the primary mechanism of action of sulfonamides?
(A) Inhibition of bacterial cell wall synthesis
(B) Inhibition of bacterial protein synthesis
(C) Inhibition of folic acid synthesis
(D) Inhibition of DNA replication

13. : Which antibiotic is commonly used to treat urinary tract infections (UTIs) due to its high renal concentration?
(A) Nitrofurantoin
(B) Vancomycin
(C) Doxycycline
(D) Levofloxacin

14. : Which antimicrobial agent is known to cause discoloration of teeth in children when used during tooth development?
(A) Tetracycline
(B) Penicillin
(C) Vancomycin
(D) Rifampin

15. : Which of the following drugs is a carbapenem antibiotic?
(A) Meropenem
(B) Ceftriaxone
(C) Azithromycin
(D) Vancomycin