Comparison between Enzyme and a Catalyst

By: Prof. Dr. Fazal Rehman Shamil | Last updated: February 3, 2024

Let me share with you a comparison between Enzyme and a Catalyst.

Aspect          Enzymes           Catalysts
Definition·        Biological molecules mostly proteins that act as catalysts in living cells.·        Catalyst can be biological or inorganic that increases the rate of chemical reactions without being consumed in the process.
Specificity·        Highly specific·        Specific but they are not as specific as enzymes.
Substrates·        Require specific substrates for catalyzing reactions.·        Do not require specific substrates, but they can accelerate various reactions.
Regulation·        Activity can be regulated by various mechanisms, including feedback inhibition and allosteric regulation.·        Generally not regulated by cellular processes
Function in·        Function within living organisms, typically in cells or within specific cellular organelles.·        Various industrial processes

·        Chemical reactions outside organisms.

Specific Names·        Enzymes are named systematically   according to the type of reaction they catalyze e.g. amylase

·        DNA polymerase

·        Catalysts are typically identified by the reaction they accelerate e.g., hydrogen peroxide catalyst
Effect on activation energy ·        Lower the activation energy required for reactions·        Lower activation energy required for reactions, but to a lesser extent compared to enzymes.
·        Generally accelerates reaction rates but to a lesser extent compared to enzymes.
Speed of reaction·        Often accelerates reaction rates by several orders of magnitude.
Enzyme-substrate complex formation·        Enzymes form temporary complexes with substrates during reactions.·        Catalysts do not typically form Specific complexes with substrates.