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Medical Genetics Multiple choice questions

1. : A nonsense mutation is _____.

(A) The creation of a different amino acid


(B) The creation of a stop codon


(C) A regulatory sequence


(D) An AG splice acceptor site



2. : Recombination occurs in meiosis is called _____.

(A) Metaphase II


(B) Prophase I


(C) Metaphase II


(D) Prophase I



3. : Condition that shows anticipation in paternal transmission is _____.

(A) Cystic fibrosis


(B) Fragile X syndrome


(C) Huntington disease


(D) Marfan syndrome



4. : Exon skipping is _____.

(A) Silent mutations


(B) RNA processing mutations


(C) Nonsense mutations


(D) Regulatory mutations



5. : Cystic fibrosis mutation consists of _____.

(A) An insertion


(B) A substitution


(C) A deletion


(D) A duplication



6. : Abnormality risk in the child with untreated phenylketonuria is _____.

(A) 100%


(B) 10%


(C) 25%


(D) 1%



7. : Recombinant alpha-iduronidase is used for _____.

(A) Pompe disease


(B) Fabry disease


(C) Gaucher disease


(D) Hurler syndrome



8. : Cancer cells exhibit _____.

(A) Avoidance of cell death


(B) Unlimited number of cell divisions


(C) Growth without external signals


(D) All of these



9. : Repeating units of nucleic acids are _____.

(A) Bases


(B) Sugar molecules


(C) Phosphate molecules


(D) Nucleotides



10. : The presence of an extra digit is called _____.

(A) Clinodactyly


(B) Polydactyly


(C) Arachnodactyly


(D) Brachydactyly



11. : DNA requires _____.

(A) Many enzymes


(B) Sunlight


(C) Protein synthase


(D) Meiotic division



12. : The nucleosome is _____.

(A) Composed of RNA


(B) Composed of DNA and RNA


(C) Found in nucleus


(D) Found in cell wall



 

 

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