Which of the following is the first antihistamine?

By: Prof. Dr. Fazal Rehman Shamil | Last updated: February 3, 2024

Question: Which of the following is the first antihistamine?

A   Piperoxan

B   Ethylenediamine

C  Alkylamines

D   Tricyclics

Answer: Piperoxan

Aspect   Description
NamePiperoxan
TypePiperoxan is the first antihistamine medication
Discovery Year1933
Discovery ResearchersJeff Forneau and Daniel Bovet
Mechanism of ActionBlocks the effects of histamine, a chemical released during allergic reactions
Medical UsesUsed to treat allergy symptoms, such as sneezing, itching, and runny nose
Commercial NamePipolphen (Brand name)
Chemical StructureA chemical structure containing a piperidine ring, characteristic of many antihistamines
Historical SignificanceOne of the earliest antihistamines to be discovered and used in medicine
AvailabilityAvailability may vary by region and brand name