Immunology MCQs

  • Which type of immunity is provided by antibodies in the blood?
    • A) Cell-mediated immunity
    • B) Humoral immunity
    • C) Innate immunity
    • D) Passive immunity
    • Answer: B) Humoral immunity
  • Which cells are primarily responsible for the production of antibodies?
    • A) T cells
    • B) B cells
    • C) Macrophages
    • D) Dendritic cells
    • Answer: B) B cells
  • What is the primary function of helper T cells?
    • A) Destroy infected cells
    • B) Produce antibodies
    • C) Activate other immune cells
    • D) Phagocytize pathogens
    • Answer: C) Activate other immune cells
  • Which of the following is an example of a primary lymphoid organ?
    • A) Spleen
    • B) Lymph node
    • C) Bone marrow
    • D) Tonsil
    • Answer: C) Bone marrow
  • Which cytokine is commonly known for its role in fever and inflammation?
    • A) Interleukin-1 (IL-1)
    • B) Interferon-gamma (IFN-γ)
    • C) Tumor necrosis factor-alpha (TNF-α)
    • D) Interleukin-6 (IL-6)
    • Answer: A) Interleukin-1 (IL-1)
  • Which type of T cell is responsible for killing infected cells?
    • A) Helper T cells
    • B) Cytotoxic T cells
    • C) Regulatory T cells
    • D) Memory T cells
    • Answer: B) Cytotoxic T cells
  • Which molecule presents antigens to T cells?
    • A) Major histocompatibility complex (MHC)
    • B) Immunoglobulin
    • C) Complement protein
    • D) Cytokine
    • Answer: A) Major histocompatibility complex (MHC)
  • Which type of hypersensitivity reaction involves IgE antibodies?
    • A) Type I hypersensitivity
    • B) Type II hypersensitivity
    • C) Type III hypersensitivity
    • D) Type IV hypersensitivity
    • Answer: A) Type I hypersensitivity
  • Which class of immunoglobulins is the first to be produced in response to an infection?
    • A) IgA
    • B) IgD
    • C) IgG
    • D) IgM
    • Answer: D) IgM
  • Which type of immunity is acquired through vaccination?
    • A) Natural active immunity
    • B) Natural passive immunity
    • C) Artificial active immunity
    • D) Artificial passive immunity
    • Answer: C) Artificial active immunity
  • What is the primary role of regulatory T cells?
    • A) To destroy pathogens
    • B) To activate B cells
    • C) To suppress immune responses
    • D) To produce antibodies
    • Answer: C) To suppress immune responses
  • Which immune cells are involved in the innate immune response?
    • A) B cells and T cells
    • B) Macrophages and neutrophils
    • C) Dendritic cells and plasma cells
    • D) Helper T cells and cytotoxic T cells
    • Answer: B) Macrophages and neutrophils
  • Which molecule is involved in the recognition of pathogen-associated molecular patterns (PAMPs)?
    • A) Toll-like receptors (TLRs)
    • B) Major histocompatibility complex (MHC)
    • C) Immunoglobulins
    • D) Complement proteins
    • Answer: A) Toll-like receptors (TLRs)
  • Which type of antibody is found predominantly in mucosal areas such as the gut?
    • A) IgG
    • B) IgA
    • C) IgM
    • D) IgE
    • Answer: B) IgA
  • Which immune response involves the production of memory cells?
    • A) Primary immune response
    • B) Secondary immune response
    • C) Innate immune response
    • D) Immediate hypersensitivity response
    • Answer: B) Secondary immune response
  • Which type of cell is involved in antigen processing and presentation?
    • A) B cells
    • B) Cytotoxic T cells
    • C) Dendritic cells
    • D) Plasma cells
    • Answer: C) Dendritic cells
  • Which component of the immune system is primarily responsible for the clearance of pathogens from the blood?
    • A) Spleen
    • B) Lymph nodes
    • C) Thymus
    • D) Bone marrow
    • Answer: A) Spleen
  • Which of the following cytokines is known for its antiviral activity?
    • A) Interferon-alpha (IFN-α)
    • B) Tumor necrosis factor-beta (TNF-β)
    • C) Interleukin-10 (IL-10)
    • D) Interleukin-2 (IL-2)
    • Answer: A) Interferon-alpha (IFN-α)
  • Which type of immune cell is involved in the direct killing of cancer cells?
    • A) Helper T cells
    • B) Cytotoxic T cells
    • C) B cells
    • D) Natural killer (NK) cells
    • Answer: D) Natural killer (NK) cells
  • Which type of hypersensitivity reaction is mediated by immune complexes?
    • A) Type I hypersensitivity
    • B) Type II hypersensitivity
    • C) Type III hypersensitivity
    • D) Type IV hypersensitivity
    • Answer: C) Type III hypersensitivity
  • Which organ is primarily responsible for the maturation of T cells?
    • A) Bone marrow
    • B) Spleen
    • C) Thymus
    • D) Lymph nodes
    • Answer: C) Thymus
  • Which class of immunoglobulins is known for its ability to cross the placenta?
    • A) IgA
    • B) IgD
    • C) IgE
    • D) IgG
    • Answer: D) IgG
  • Which immune cells are the first responders to infection and are often associated with acute inflammation?
    • A) Macrophages
    • B) Neutrophils
    • C) B cells
    • D) T cells
    • Answer: B) Neutrophils
  • Which type of immunity involves the transfer of antibodies from mother to infant through breast milk?
    • A) Natural active immunity
    • B) Natural passive immunity
    • C) Artificial active immunity
    • D) Artificial passive immunity
    • Answer: B) Natural passive immunity
  • Which type of T cell regulates immune responses and prevents autoimmunity?
    • A) Helper T cells
    • B) Cytotoxic T cells
    • C) Regulatory T cells
    • D) Memory T cells
    • Answer: C) Regulatory T cells
  • Which type of immune response is enhanced by vaccination?
    • A) Innate immune response
    • B) Secondary immune response
    • C) Immediate hypersensitivity response
    • D) Acute phase response
    • Answer: B) Secondary immune response
  • Which type of cell is responsible for phagocytosis of pathogens in the immune system?
    • A) B cells
    • B) Helper T cells
    • C) Macrophages
    • D) Plasma cells
    • Answer: C) Macrophages
  • Which of the following is a hallmark of autoimmune diseases?
    • A) Immune tolerance to self-antigens
    • B) Overproduction of antibodies
    • C) Immune response against self-antigens
    • D) Deficiency in immune cell function
    • Answer: C) Immune response against self-antigens
  • Which type of cell is responsible for the immediate allergic reaction in Type I hypersensitivity?
    • A) B cells
    • B) Helper T cells
    • C) Mast cells
    • D) Cytotoxic T cells
    • Answer: C) Mast cells
  • Which cytokine is known for its role in the differentiation of T cells into Th1 or Th2 subsets?
    • A) Interleukin-4 (IL-4)
    • B) Interleukin-6 (IL-6)
    • C) Interleukin-12 (IL-12)
    • D) Tumor necrosis factor-alpha (TNF-α)
    • Answer: C) Interleukin-12 (IL-12)
  • Which of the following is a key function of antibodies?
    • A) Antigen processing
    • B) Pathogen phagocytosis
    • C) Neutralization of toxins
    • D) Activation of T cells
    • Answer: C) Neutralization of toxins
  • Which cell surface molecule is involved in antigen presentation to T cells?
    • A) CD4
    • B) CD8
    • C) T cell receptor (TCR)
    • D) Major histocompatibility complex (MHC)
    • Answer: D) Major histocompatibility complex (MHC)
  • Which of the following is a characteristic feature of anaphylaxis?
    • A) Chronic inflammation
    • B) Systemic vasodilation
    • C) Delayed hypersensitivity
    • D) Autoimmune response
    • Answer: B) Systemic vasodilation
  • Which of the following is a key characteristic of a memory cell?
    • A) Short-lived
    • B) High proliferation capacity
    • C) Long-lived
    • D) Immediate response
    • Answer: C) Long-lived
  • Which type of immune response is characterized by the activation of the complement system?
    • A) Innate immune response
    • B) Adaptive immune response
    • C) Humoral immune response
    • D) Cell-mediated immune response
    • Answer: A) Innate immune response
  • Which of the following is NOT a characteristic of innate immunity?
    • A) Specificity for pathogens
    • B) Rapid response
    • C) Involvement of physical barriers
    • D) Presence of phagocytic cells
    • Answer: A) Specificity for pathogens
  • Which immune cell type is most commonly associated with chronic inflammation?
    • A) Neutrophils
    • B) Eosinophils
    • C) Monocytes/macrophages
    • D) Basophils
    • Answer: C) Monocytes/macrophages
  • Which cytokine is involved in the activation of macrophages and is also known as a macrophage-activating factor?
    • A) Interleukin-1 (IL-1)
    • B) Interferon-gamma (IFN-γ)
    • C) Tumor necrosis factor-alpha (TNF-α)
    • D) Interleukin-10 (IL-10)
    • Answer: B) Interferon-gamma (IFN-γ)
  • Which of the following is a primary function of complement proteins?
    • A) Antigen recognition
    • B) Antibody production
    • C) Pathogen lysis
    • D) Cytokine secretion
    • Answer: C) Pathogen lysis
  • Which type of cell is involved in the initial detection of pathogens and the activation of the adaptive immune response?
    • A) T cells
    • B) B cells
    • C) Dendritic cells
    • D) Plasma cells
    • Answer: C) Dendritic cells
  • Which of the following is a characteristic of Type IV hypersensitivity?
    • A) Immediate response
    • B) Mediated by IgE
    • C) Delayed response
    • D) Involves immune complexes
    • Answer: C) Delayed response
  • Which of the following immune cells produces cytokines that promote the differentiation of B cells into plasma cells?
    • A) Helper T cells
    • B) Cytotoxic T cells
    • C) B cells
    • D) Macrophages
    • Answer: A) Helper T cells
  • Which type of immune response is activated by the recognition of pathogen-associated molecular patterns (PAMPs)?
    • A) Adaptive immune response
    • B) Innate immune response
    • C) Humoral immune response
    • D) Cell-mediated immune response
    • Answer: B) Innate immune response
  • Which term describes the immune response that occurs when the body mounts an immune reaction against its own tissues?
    • A) Autoimmunity
    • B) Hypersensitivity
    • C) Immunodeficiency
    • D) Alloimmunity
    • Answer: A) Autoimmunity
  • Which immune cells are involved in the destruction of parasites such as helminths?
    • A) Neutrophils
    • B) Eosinophils
    • C) Basophils
    • D) Macrophages
    • Answer: B) Eosinophils
  • Which process describes the ability of antibodies to enhance the phagocytosis of pathogens?
    • A) Opsonization
    • B) Neutralization
    • C) Complement activation
    • D) Agglutination
    • Answer: A) Opsonization
  • Which of the following is NOT a component of the complement system?
    • A) Complement proteins
    • B) Antibodies
    • C) Phagocytes
    • D) Cytokines
    • Answer: D) Cytokines
  • Which type of T cell is responsible for providing help to B cells in antibody production?
    • A) Helper T cells
    • B) Cytotoxic T cells
    • C) Regulatory T cells
    • D) Memory T cells
    • Answer: A) Helper T cells
  • Which type of immunity is characterized by the use of monoclonal antibodies for treatment?
    • A) Natural active immunity
    • B) Natural passive immunity
    • C) Artificial active immunity
    • D) Artificial passive immunity
    • Answer: D) Artificial passive immunity
  • Which term describes the immune system’s ability to distinguish between self and non-self?
    • A) Immune tolerance
    • B) Immune surveillance
    • C) Immune specificity
    • D) Immune memory
    • Answer: C) Immune specificity