Difference between CT scan and PET scan

By: Prof. Dr. Fazal Rehman Shamil | Last updated: February 3, 2024

Difference between CT scan and PET scan:
Doctors may use CT scans and PET scans for various medical purposes. Let us discuss both of these in detail:

 

Aspect          CT Scan PET Scan
Full formComputed TomographyPositron Emission Tomography
Year of discovery Discovered in the early 1970s.Discovered in the mid-20th century, with the first successful PET scan performed in the 1950s.
Discovered bySir Godfrey Hounsfield and Dr. Allan CormackDr. David E. Kuhl and Dr. Roy H. Hounsfield
Principle of ImagingUtilizes X-rays to create detailed cross-sectional images of anatomical structures.Injects a radioactive tracer to visualize the metabolic activity and cellular functions within tissues.
Purpose of imaging Focuses on providing high-resolution anatomical images.Primarily used to display metabolic processes and to detect areas with abnormal glucose metabolism.
Radiation ExposureInvolves exposure to X-ray radiation, which can vary.Also involves radiation exposure due to the radioactive tracer, but the exposure time is limited.
Clinical ApplicationsIt is used in the diagnoses of conditions such as fractures, tumors, infections and internal injuries.It is particularly useful for cancer detection, its staging and monitoring the treatment response.
Combined ScansIt is not typically combined with other scans.It can be combined with CT scans to provide both anatomical and functional information (PET/CT scan).
Interpretation of Image Provides detailed anatomical structures, which need interpretation by a radiologist or medical professional.Shows areas of increased tracer uptake, indicating higher metabolic activity. It also requires interpretation by specialists.
Contrast AgentsOften uses contrast agents (dyes) to enhance the visibility of certain structures.It does not use traditional contrast agents. It relies on the injected radioactive tracer for imaging.
Duration of ProcedureIt is generally a quicker procedure that typically performed within a few minutes.PET scans may take longer due to the time needed for the radioactive tracer to distribute within the body which may usually upto 1-2 hours.
Common UsesThis technique is used for diagnosing injuries, infections, vascular diseases, and various internal conditions.This technique is particularly used in cancer diagnosis, treatment monitoring, and evaluation of neurological disorders.