Let me share with you a comparison between Smooth endoplasmic reticulum and Rough endoplasmic reticulum.
| Aspect | SER | RER |
| Full form | · Smooth Endoplasmic Reticulum | · Rough Endoplasmic Reticulum |
| Structure and Appearance | · Lacks ribosomes on its surface, giving it a smooth appearance | · Studded with ribosomes on its surface, giving it a rough or granular appearance. |
| Detoxification | · Contains enzymes for detoxifying drugs and toxins | · Not directly involved in drug detoxification and metabolism |
| Calcium Storage | · Stores and regulates calcium ions in muscle cells | · Not involved in calcium storage or regulation |
| Location | · liver cells (hepatocytes) · adipocytes · Cells involved in lipid metabolism | · Also found in various cell types, including cells that secrete proteins and enzymes, such as pancreatic cells. |
| Functions | · Lipid metabolism · Detoxification · Calcium storage | · Protein synthesis · Folding and modification · Secretory protein production |