Basic Epidemiology & Biostatistics Important Questions – Past Papers

By: Prof. Fazal Rehman Shamil

Paper 1: Basic Epidemiology & Biostatistics – University Past Papers.

Time Allowed: 3 hours

Total Marks:    70, Passing Marks (35)

Q.1 Differentiate:-
1. Monitoring and surveillance (3) 2. Quarantine and isolation (4)
3. Incubation period and latent period (3) 4. Cross infection and iatrogenic infection (4)

Q.2 Write a note on:-
1. Advantages of the mean. (4) 2. Gaussian. (6) 3. Skewed curves. (4)

Q.3 80 persons attended a buffet dinner at a 5-star hotel. 25 persons developed vomiting and diarrhea
within 6 hours. Following data was gathered.

 

Food Served

            Consumed food Did not consume food
Food poisoning + No food poisoning Food poisoning + No food poisoning
Mutton Karahi 20 28 5 7
Chicken Boti 12 17 13 18
Finger Fish 15 24 10 11
Kofta Kabab 18 26 7 9
Fresh Salad 23 24 2 11
Kheer 22 34 3 1

What is incriminated food item that most likely caused the food poisoning? Also, comment on the reason. (14)

Q.4 a. Wilson described the criterion for the screening of diseases. Describe his criterion. (4)
b. A new screening test was assessed against gold standards i,e biopsy for breast cancer detection.
Out of 1600 females of 40 years & above, 240 ladies were declared to be with the disease in comparison to 140 who conformed with the disease on biopsy. Sixty were found to be positive both on screening as well as biopsy.
a. Calculate sensitivity, specificity, and predictive values of the screening test. (8)
and interpret your results.
b. Give your opinion regarding the usefulness of the new tests in the light of sensitivity and specificity. (2)
c. For a clinician, out of sensitivity, specificity, and positive predictive value of screening test which measure is of more use & why. (4)

Q.5 Describe in detail, cross over and concurrent parallel type of study designs. (14)

Q.6 Define sampling? Describe various types of sampling. (14)

Q.7 How will you investigate an epidemic of Hepatitis E.? Give all salient points. (14)

Q.8 Write a note on:-
1. Ogive (5) 2. Census (6) 3. Matching (3)

Paper 2: Basic Epidemiology & Biostatistics – University Past Papers.

Time Allowed: 3 hours

Total Marks:    70, Passing Marks (35)

Q.1 What is your understanding of the followings:-
1. Masking (2)
2. Confounding (2)
3. Epidemiology (2)
4. Host of disease (2)
5. Census (2)
6. Randomization (2)
7. Epidemic curve (2)

Q.2 Differentiate:-
1. Simple table and cumulative frequency table. (3)
2. Case-control and cohort studies. (7)
3. Screening test and diagnostic test. (4)

Q.3 A researcher wanted to see the relationship between crime and genetic makeup. He inducted 480 persons into the study. Of 240 criminals, 40 had a parental history of crime. From the other group, 10 had a positive history.
a. Name the study. (1)
b. Construct a 2×2 table. (3)
c. Calculate the relevant measure of association and interpret the result. (10)

Q.4 a. Wilson described the criterion for the screening of diseases. Describe his criterion. (6)
b. A researcher conducted a study to evaluate a new screening test for carcinoma breast in 300
females. Out of 70 diagnosed cases, 54 were picked up by screening tests. The screening test also picked 26 from biopsy negative women.

Calculate sensitivity, specificity, and predictive values and interpret results. (8)

Q.5 a, Describe in detail, incidence, and prevalence. (7)
b. Give cross over type of study design. What are its advantages & disadvantages? (7)

Q.6 Define sampling. Describe various types of sampling. (14)

Q.7 How will you investigate an epidemic of cholera?
Give all salient points. (14)

Q.8 Write a note on:-
1. Ogive (5)
2. Normal curve (6)
3. Matching (3)

 

Prof. Fazal Rehman Shamil